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Frans A. A. Mulder

Frans A. A. Mulder

D-Index & Metrics

Chemistry

D-Index
44
Citations
7871
World Ranking
16766
National Ranking
136

Overview

Frans A. A. Mulder is affiliated with Aarhus University in Denmark and has contributed extensively to the field of Biochemistry, Genetics and Molecular Biology. Their research primarily focuses on molecular biology, spectroscopy, and materials chemistry, with additional work related to nuclear and high energy physics as well as physiology.

The scientist's main research topics include protein structure and dynamics, advanced NMR techniques and applications, enzyme structure and function, metabolomics and mass spectrometry studies, NMR spectroscopy and applications, RNA and protein synthesis mechanisms, and Parkinson's disease mechanisms and treatments.

Recent publications reflect a broad spectrum of their expertise and collaborative efforts. Notable papers include:

  • ODiNPred: comprehensive prediction of protein order and disorder, 2020, Scientific Reports
  • CheSPI: chemical shift secondary structure population inference, 2021, Journal of Biomolecular NMR
  • Solvent paramagnetic relaxation enhancement as a versatile method for studying structure and dynamics of biomolecular systems, 2022, Progress in Nuclear Magnetic Resonance Spectroscopy
  • Predicting NMR relaxation of proteins from molecular dynamics simulations with accurate methyl rotation barriers, 2020, The Journal of Chemical Physics
  • Genetic Variance of Metabolomic Features and Their Relationship With Malting Quality Traits in Spring Barley, 2020, Frontiers in Plant Science

Frequent co-authors working with Frans Mulder include Jakob T. Nielsen, Rupashree Dass, Daniel E. Otzen, Camilla Andersen, and Janni Nielsen.

The scientist has published multiple papers in several prominent venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biomolecular NMR
  • Biochemistry
  • Methods in molecular biology
  • Biomolecular NMR Assignments

Frans Mulder has also contributed to book publications, notably with Frontiers Media, including the title "The Development and Utilization of Novel Antibiotic Alternatives" released in 2022.

Best Publications

  • Slow Dynamics in Folded and Unfolded States of an SH3 Domain

    Martin Tollinger;Nikolai R. Skrynnikov;Frans A. A. Mulder;Julie D. Forman-Kay,†,§ and

  • Studying excited states of proteins by NMR spectroscopy

    Frans A.A. Mulder;Anthony Mittermaier;Bin Hon;Frederick W. Dahlquist

  • Measurement of Slow (μs−ms) Time Scale Dynamics in Protein Side Chains by 15N Relaxation Dispersion NMR Spectroscopy: Application to Asn and Gln Residues in a Cavity Mutant of T4 Lysozyme

    Frans A. A. Mulder;Nikolai R. Skrynnikov;Bin Hon;Frederick W. Dahlquist

  • Latent and active p53 are identical in conformation.

    Ayeda Ayed;Frans A.A. Mulder;Gwan-Su Yi;Ying Lu

  • Sequence-Specific Random Coil Chemical Shifts of Intrinsically Disordered Proteins

    Kamil Tamiola;Burcin Acar;Frans A. A. Mulder

  • Altered flexibility in the substrate-binding site of related native and engineered high-alkaline Bacillus subtilisins.

    Frans A.A Mulder;Dick Schipper;Richard Bott;Rolf Boelens

  • Probing slow time scale dynamics at methyl-containing side chains in proteins by relaxation dispersion NMR measurements: application to methionine residues in a cavity mutant of T4 lysozyme.

    Nikolai R. Skrynnikov;Frans A. A. Mulder;Bin Hon;Frederick W. Dahlquist

  • NMR chemical shift data and ab initio shielding calculations: emerging tools for protein structure determination

    Frans A. A. Mulder;Michael Filatov

  • How Epigallocatechin Gallate Can Inhibit α-Synuclein Oligomer Toxicity in Vitro

    Nikolai Lorenzen;Søren B. Nielsen;Yuichi Yoshimura;Brian S. Vad

  • Distribution of molecular size within an unfolded state ensemble using small-angle X-ray scattering and pulse field gradient NMR techniques.

    Wing-Yiu Choy;Frans A.A. Mulder;Karin A. Crowhurst;D.R. Muhandiram

  • Structural and dynamic changes of photoactive yellow protein during its photocycle in solution.

    Gilles Rubinstenn;Geerten W. Vuister;Geerten W. Vuister;Frans A. A. Mulder;Petra E. Düx

  • POTENCI: prediction of temperature, neighbor and pH-corrected chemical shifts for intrinsically disordered proteins.

    Jakob Toudahl Nielsen;Frans A A Mulder

  • Solution structure and backbone dynamics of the photoactive yellow protein.

    Petra Düx;Gilles Rubinstenn;Geerten W. Vuister;Rolf Boelens

  • An Off-resonance Rotating Frame Relaxation Experiment for the Investigation of Macromolecular Dynamics Using Adiabatic Rotations

    Frans A.A. Mulder;Robin A. de Graaf;Robert Kaptein;Rolf Boelens

  • The ribosomal stalk binds to translation factors IF2, EF-Tu, EF-G and RF3 via a conserved region of the L12 C-terminal domain.

    Magnus Helgstrand;Chandra S. Mandava;Frans A.A. Mulder;Anders Liljas

  • Using NMR chemical shifts to calculate the propensity for structural order and disorder in proteins.

    Kamil Tamiola;Frans A. A. Mulder

  • Slow Internal Dynamics in Proteins: Application of NMR Relaxation Dispersion Spectroscopy to Methyl Groups in a Cavity Mutant of T4 Lysozyme

    Frans A A Mulder;Bin Hon;Anthony Mittermaier;Frederick W Dahlquist

  • Residue-specific pK(a) determination of lysine and arginine side chains by indirect N-15 and C-13 NMR spectroscopy: Application to apo calmodulin

    Ingemar Andre;Sara Linse;Frans A. A. Mulder

  • Flexibility and ligand exchange in a buried cavity mutant of T4 lysozyme studied by multinuclear NMR.

    Mulder Fa;Hon B;Muhandiram Dr;Dahlquist Fw

  • Improved HSQC experiments for the observation of exchange broadened signals.

    Frans A. A. Mulder;Chris A. E. M. Spronk;Monique Slijper;Robert Kaptein

Frequent Co-Authors

Rolf Boelens
Rolf Boelens Utrecht University
Frederick W. Dahlquist
Frederick W. Dahlquist University of California, Santa Barbara
Lewis E. Kay
Lewis E. Kay University of Toronto
Mikael Akke
Mikael Akke Lund University
Robert Kaptein
Robert Kaptein Utrecht University
Sara Linse
Sara Linse Lund University
Daniel E. Otzen
Daniel E. Otzen Aarhus University
Geerten W. Vuister
Geerten W. Vuister University of Leicester
Kazuyuki Akasaka
Kazuyuki Akasaka Kyoto Prefectural University of Medicine

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