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Klaas J. Hellingwerf

Klaas J. Hellingwerf

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Chemistry
Netherlands
2025
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Biology and Biochemistry
Netherlands
2023

D-Index & Metrics

Chemistry

D-Index
88
Citations
23833
World Ranking
2332
National Ranking
54

Biology and Biochemistry

D-Index
89
Citations
25134
World Ranking
2599
National Ranking
62

Research.com Recognitions

  • 2025 - Research.com Chemistry in Netherlands Leader Award
  • 2023 - Research.com Biology and Biochemistry in Netherlands Leader Award
  • 2022 - Research.com Chemistry in Netherlands Leader Award

Overview

Klaas J. Hellingwerf is affiliated with the University of Amsterdam in the Netherlands, and their research primarily spans biochemistry, genetics, and molecular biology. Their scholarly output reflects a focus on multiple subfields, including molecular biology, renewable energy, sustainability and the environment, cellular and molecular neuroscience, biomaterials, and physiology.

The scientist's work concentrates on several prominent topics, such as photosynthetic processes and mechanisms, algal biology and biofuel production, photoreceptor and optogenetics research, protist diversity and phylogeny, microbial metabolic engineering and bioproduction, biodegradable polymer synthesis and properties, and enzyme catalysis and immobilization.

Recent publications highlight these thematic areas. Notable papers include:

  • Industrial Production of Poly-β-hydroxybutyrate from CO2: Can Cyanobacteria Meet this Challenge? (2020, Processes)
  • Confinement in crystal lattice alters entire photocycle pathway of the Photoactive Yellow Protein (2020, Nature Communications)
  • Blue light induces major changes in the gene expression profile of the cyanobacterium Synechocystis sp. PCC 6803 (2020, Physiologia Plantarum)
  • Using osmotic stress to stabilize mannitol production in Synechocystis sp. PCC6803 (2020, Biotechnology for Biofuels)
  • Photoreaction Dynamics of a Full-Length Protein YtvA and Intermolecular Interaction with RsbRA (2020, Biochemistry)

Frequent collaborators in Klaas J. Hellingwerf's research include Wen-Yang Wu, Filipe Branco dos Santos, W. Du, Ruth Pérez Gallego, and Aniek D. van der Woude. These partnerships have contributed to multiple publications, underscoring a networked approach to the scientist's work.

Their studies have appeared in diverse publication venues, reflecting interdisciplinary engagement. These venues include Processes, Nature Communications, Physiologia Plantarum, Biotechnology for Biofuels, and Biochemistry.

Best Publications

  • Dynamics of cell wall structure in Saccharomyces cerevisiae.

    Frans M Klis;Pieternella Mol;Klaas Hellingwerf;Stanley Brul

  • Potential of industrial biotechnology with cyanobacteria and eukaryotic microalgae

    René H Wijffels;Olaf Kruse;Klaas J Hellingwerf

  • Photoreceptor Proteins, "Star Actors of Modern Times": A Review of the Functional Dynamics in the Structure of Representative Members of Six Different Photoreceptor Families

    Michael A. Van Der Horst;Klaas J. Hellingwerf

  • Molecular organization of the cell wall of Candida albicans

    F.M. Klis;P.W.J. de Groot;K.J. Hellingwerf

  • The eubacterium Ectothiorhodospira halophila is negatively phototactic, with a wavelength dependence that fits the absorption spectrum of the photoactive yellow protein.

    W W Sprenger;W D Hoff;J P Armitage;K J Hellingwerf

  • Energy transduction on the nanosecond time scale: early structural events in a xanthopsin photocycle.

    Benjamin Perman;Vukica Šrajer;Zhong Ren;Tsu-yi Teng

  • Genome‐wide identification of fungal GPI proteins

    Piet W. J. de Groot;Klaas J. Hellingwerf;Frans M. Klis

  • Proteomic Analysis of Candida albicans Cell Walls Reveals Covalently Bound Carbohydrate-Active Enzymes and Adhesins

    Piet W. J. de Groot;Albert D. de Boer;Jeff Cunningham;Henk L. Dekker

  • Thiol ester-linked p-coumaric acid as a new photoactive prosthetic group in a protein with rhodopsin-like photochemistry

    W. D. Hoff;P. Dux;K. Hard;B. Devreese

  • Photoactive Yellow Protein, A New Type of Photoreceptor Protein: Will This "Yellow Lab" Bring Us Where We Want to Go? |

    Klaas J. Hellingwerf;Johnny Hendriks;Thomas Gensch

  • Energy biotechnology with cyanobacteria.

    S Andreas Angermayr;Klaas J Hellingwerf;Peter Lindblad;M Joost Teixeira de Mattos

  • Measurement and global analysis of the absorbance changes in the photocycle of the photoactive yellow protein from Ectothiorhodospira halophila

    W. D. Hoff;I. H. M. Van Stokkum;H. J. Van Ramesdonk;M. E. Van Brederode

  • Metabolic engineering of cyanobacteria for the synthesis of commodity products

    S. Andreas Angermayr;Aleix Gorchs Rovira;Klaas J. Hellingwerf

  • Phototransformation of Green Fluorescent Protein with Uv and Visible Light Leads to Decarboxylation of Glutamate 222

    J.J. van Thor;T. Gensch;K.J. Hellingwerf;L.N. Johnson

  • Formation of a new buried charge drives a large-amplitude protein quake in photoreceptor activation.

    Aihua Xie;Lorand Kelemen;Johnny Hendriks;Brandy J. White

  • Evidence for trans-cis isomerization of the p-coumaric acid chromophore as the photochemical basis of the photocycle of photoactive yellow protein

    R Kort;H Vonk;X Xu;W.D Hoff

  • Specific detection and analysis of a probiotic Bifidobacterium strain in infant feces.

    R G Kok;A de Waal;F Schut;G W Welling

  • The Effect of 'Probe Binding' on the Quantitative Determination of the Proton-Motive Force in Bacteria

    Juke S. Lolkema;Klaas J. Hellingwerf;Wil N. Konings

  • Engineering cyanobacteria for direct biofuel production from CO2

    Philipp Savakis;Klaas J Hellingwerf

  • Glu46 Donates a Proton to the 4-Hydroxycinnamate Anion Chromophore During the Photocycle of Photoactive Yellow Protein †

    Aihua Xie;Wouter D. Hoff;and Arthur R. Kroon;Klaas J. Hellingwerf

Frequent Co-Authors

Wim Crielaard
Wim Crielaard Academic Center for Dentistry Amsterdam
Ivo H. M. van Stokkum
Ivo H. M. van Stokkum Vrije Universiteit Amsterdam
Hans V. Westerhoff
Hans V. Westerhoff Vrije Universiteit Amsterdam
Rienk van Grondelle
Rienk van Grondelle Vrije Universiteit Amsterdam
John T. M. Kennis
John T. M. Kennis Vrije Universiteit Amsterdam
Stanley Brul
Stanley Brul University of Amsterdam
Rolf Boelens
Rolf Boelens Utrecht University
Robert Kaptein
Robert Kaptein Utrecht University
Frans M. Klis
Frans M. Klis University of Amsterdam
Ben Vosman
Ben Vosman Wageningen University & Research

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