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Andreas Bechthold

Andreas Bechthold

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
10465
World Ranking
12742
National Ranking
908

Overview

Andreas Bechthold is affiliated with the University of Freiburg in Germany and has contributed extensively to research in biochemistry, genetics, and molecular biology as well as medicine. Their scholarly activities focus primarily on molecular biology and pharmacology, with additional contributions in plant science, organic chemistry, and biotechnology.

Their research prominently addresses microbial natural products and biosynthesis, genomics and phylogenetic studies, and plant-microbe interactions and immunity. Additional thematic areas include carbohydrate chemistry and synthesis, marine sponges and natural products, synthetic organic chemistry methods, and plant biochemistry and biosynthesis.

Bechthold's publication record includes papers in a range of academic venues, with frequent contributions to Phytochemistry Letters, ChemBioChem, Microorganisms, Microbiology Resource Announcements, and Applied Microbiology and Biotechnology. The topics covered span molecular mechanisms underlying natural product biosynthesis and related microbial processes.

  • Intratumoral delivered novel circular mRNA encoding cytokines for immune modulation and cancer therapy, 2022, Molecular Therapy - Nucleic Acids
  • Effects of addition of elicitors on rimocidin biosynthesis in Streptomyces rimosus M527, 2020, Applied Microbiology and Biotechnology
  • Identification of a gene from Streptomyces rimosus M527 negatively affecting rimocidin biosynthesis and morphological differentiation, 2020, Applied Microbiology and Biotechnology
  • Secondary nucleotide messenger c-di-GMP exerts a global control on natural product biosynthesis in streptomycetes, 2020, Nucleic Acids Research
  • Role of Two Exceptional trans Adenylation Domains and MbtH-like Proteins in the Biosynthesis of the Nonribosomal Peptide WS9324A from Streptomyces calvus ATCC 13382, 2020, ChemBioChem

Frequent co-authors include:

  • Zheng Ma
  • Xiaoping Yu
  • Roman Makitrynskyy
  • Olga Tsypik
  • Yongyong Zhang

Bechthold's publication output comprises 58 works classified under biochemistry, genetics, and molecular biology, alongside 47 contributions related to medicine. The subfields emphasize molecular biology and pharmacology substantially, reflecting a focus on the biochemical pathways and therapeutic potentials of microbial products and natural compounds.

Best Publications

  • Minimum Information about a Biosynthetic Gene cluster.

    Marnix H. Medema;Marnix H. Medema;Renzo Kottmann;Pelin Yilmaz;Matthew Cummings

  • Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork

    Christian Hertweck;Andriy Luzhetskyy;Yuri Rebets;Andreas Bechthold

  • SimReg1 is a master switch for biosynthesis and export of simocyclinone D8 and its precursors

    Liliya Horbal;Yuriy Rebets;Mariya Rabyk;Roman Makitrynskyy

  • Chemical and biochemical aspects of deoxysugars and deoxysugar oligosaccharides

    Andreas Kirschning;Andreas F. W. Bechthold;Jürgen Rohr

  • Genes and enzymes involved in deoxysugar biosynthesis in bacteria

    A Trefzer;J A Salas;A Bechthold

  • Genes and Enzymes Involved in Caffeic Acid Biosynthesis in the Actinomycete Saccharothrix espanaensis

    Martin Berner;Daniel Krug;Corina Bihlmaier;Andreas Vente

  • The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tü22: sequence analysis and expression in a heterologous host

    Koji Ichinose;Koji Ichinose;David J. Bedford;Diethild Tornus;Andreas Bechthold

  • Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces viridochromogenes Tü57 and production of new antibiotics

    G Weitnauer;A Mühlenweg;A Trefzer;D Hoffmeister

  • Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis

    Lucia Westrich;Silvie Domann;Bettina Faust;David Bedford

  • Biosynthetic Gene Cluster of Simocyclinone, a Natural Multihybrid Antibiotic

    A. Trefzer;S. Pelzer;J. Schimana;S. Stockert

  • Cloning of an avilamycin biosynthetic gene cluster from Streptomyces viridochromogenes Tü57.

    Sibylle Gaisser;Axel Trefzer;Sigrid Stockert;Andreas Kirschning

  • A genomic screening approach to the structure-guided identification of drug candidates from natural sources.

    Andreas Hornung;Marcelo Bertazzo;Agnieszka Dziarnowski;Kathrin Schneider

  • Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tü2717.

    B. Faust;D. Hoffmeister;G. Weitnauer;L. Westrich

  • The Glycosyltransferase UrdGT2 Catalyzes Both C- and O-Glycosidic Sugar Transfers

    Clemens Dürr;Dirk Hoffmeister;Dirk Hoffmeister;Sven-Eric Wohlert;Koji Ichinose

  • The NDP-sugar co-substrate concentration and the enzyme expression level influence the substrate specificity of glycosyltransferases: cloning and characterization of deoxysugar biosynthetic genes of the urdamycin biosynthetic gene cluster

    D Hoffmeister;K Ichinose;S Domann;S Domann;B Faust

  • Site-specific recombination strategies for engineering actinomycete genomes.

    Simone Herrmann;Theresa Siegl;Marta Luzhetska;Lutz Petzke

  • Identification of a sugar flexible glycosyltransferase from Streptomyces olivaceus, the producer of the antitumor polyketide elloramycin

    Gloria Blanco;Eugenio P Patallo;Alfredo F Braña;Axel Trefzer

  • Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.

    Axel Trefzer;Gloria Blanco;Lily Remsing;Eva Künzel

  • Function of glycosyltransferase genes involved in urdamycin A biosynthesis

    A. Trefzer;D. Hoffmeister;E. Künzel;S. Stockert

  • Ubiquinone biosynthesis. Cloning of the genes coding for chorismate pyruvate-lyase and 4-hydroxybenzoate octaprenyl transferase from Escherichia coli.

    M. Siebert;A. Bechthold;M. Melzer;U. May

Frequent Co-Authors

Jürgen Rohr
Jürgen Rohr University of Kentucky
José A. Salas
José A. Salas University of Oviedo
Carmen Méndez
Carmen Méndez University of Oviedo
Lutz Heide
Lutz Heide University of Tübingen
Bernhard Breit
Bernhard Breit University of Freiburg
Rolf Müller
Rolf Müller Saarland University
Steffen J. Glaser
Steffen J. Glaser Technical University of Munich
Kazufumi Yazaki
Kazufumi Yazaki Kyoto University
Jon S. Thorson
Jon S. Thorson University of Kentucky
Christian Hertweck
Christian Hertweck Friedrich Schiller University Jena

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