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Carmen Méndez

Carmen Méndez

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Biology and Biochemistry
Spain
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
14511
World Ranking
6451
National Ranking
104

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Spain Leader Award

Overview

Carmen Méndez is affiliated with the University of Oviedo in Spain. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with particular focus on Pharmacology, Molecular Biology, and Organic Chemistry among other subfields.

The scientist's work has concentrated on several main topics, including:

  • Microbial Natural Products and Biosynthesis
  • Genomics and Phylogenetic Studies
  • Synthetic Organic Chemistry Methods
  • Marine Sponges and Natural Products
  • Essential Oils and Antimicrobial Activity
  • Chemical Synthesis and Analysis
  • Phytochemical compounds biological activities

Méndez has co-authored frequently with several researchers including José A. Salas, Carlos Olano, Mónica G. Malmierca, Lorena Cuervo, and Catherine Bresee.

Their recent publications cover a range of topics and include the following works:

  • Colibrimycins, Novel Halogenated Hybrid Polyketide Synthase-Nonribosomal Peptide Synthetase (PKS-NRPS) Compounds Produced by Streptomyces sp. Strain CS147, 2021, Applied and Environmental Microbiology
  • Discovery of Cryptic Largimycins in Streptomyces Reveals Novel Biosynthetic Avenues Enriching the Structural Diversity of the Leinamycin Family, 2020, ACS Chemical Biology
  • The Volatile Organic Compounds of Streptomyces spp.: An In-Depth Analysis of Their Antifungal Properties, 2023, Microorganisms
  • Genetic Engineering in Combination with Semi-Synthesis Leads to a New Route for Gram-Scale Production of the Immunosuppressive Natural Product Brasilicardin A, 2021, Angewandte Chemie International Edition
  • Volatile Compounds in Actinomycete Communities: A New Tool for Biosynthetic Gene Cluster Activation, Cooperative Growth Promotion, and Drug Discovery, 2022, Cells

Méndez has disseminated research in several frequent publication venues, including:

  • The Journal of Urology
  • Microorganisms
  • Zenodo (CERN European Organization for Nuclear Research)
  • ACS Chemical Biology
  • Microbial Biotechnology

Best Publications

  • Minimum Information about a Biosynthetic Gene cluster.

    Marnix H. Medema;Marnix H. Medema;Renzo Kottmann;Pelin Yilmaz;Matthew Cummings

  • Indolocarbazole natural products: occurrence, biosynthesis, and biological activity

    César Sánchez;Carmen Méndez;José A. Salas

  • Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering.

    Carlos Olano;Felipe Lombó;Carmen Méndez;José A. Salas

  • Antitumor Compounds from Marine Actinomycetes

    Carlos Olano;Carmen Méndez;Jose A P Salas

  • Combinatorial biosynthesis of antitumor indolocarbazole compounds

    César Sánchez;Lili Zhu;Alfredo F. Braña;Aaroa P. Salas

  • The Biosynthetic Gene Cluster for the Antitumor Rebeccamycin: Characterization and Generation of Indolocarbazole Derivatives

    César Sánchez;Igor A Butovich;Alfredo F Braña;Jürgen Rohr

  • Two glycosyltransferases and a glycosidase are involved in oleandomycin modification during its biosynthesis by Streptomyces antibioticus

    Luis M. Quirós;Ignacio Aguirrezabalaga;Carlos Olano;Carmen Méndez

  • Identification of Two Genes from Streptomyces argillaceus Encoding Glycosyltransferases Involved in Transfer of a Disaccharide during Biosynthesis of the Antitumor Drug Mithramycin

    Ernestina Fernández;Ulrike Weißbach;César Sánchez Reillo;Alfredo F. Braña

  • Altering the glycosylation pattern of bioactive compounds.

    Carmen Méndez;José A Salas

  • The developmental fate of S. coelicolor hyphae depends upon a gene product homologous with the motility σ factor of B. subtilis

    Keith F. Chater;Celia J. Bruton;Kitty A. Plaskitt;Mark J. Buttner

  • Deciphering the biosynthesis pathway of the antitumor thiocoraline from a marine actinomycete and its expression in two Streptomyces species

    Felipe Lombó;Ana Velasco;Angelina Castro;Fernando de la Calle

  • Activation and identification of five clusters for secondary metabolites in Streptomyces albus J1074

    Carlos Olano;Ignacio García;Aranzazu González;Miriam Rodriguez

  • A Regioselective Tryptophan 5-Halogenase Is Involved in Pyrroindomycin Biosynthesis in Streptomyces rugosporus LL-42D005

    Susanne Zehner;Alexander Kotzsch;Bojan Bister;Roderich D. Süssmuth

  • The aureolic acid family of antitumor compounds: structure, mode of action, biosynthesis, and novel derivatives

    Felipe Lombó;Nuria Menéndez;José A. Salas;Carmen Méndez

  • Post-PKS tailoring steps in natural product-producing actinomycetes from the perspective of combinatorial biosynthesis.

    Carlos Olano;Carmen Méndez;José A. Salas

  • Engineering the glycosylation of natural products in actinomycetes

    José A. Salas;Carmen Méndez

  • Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.

    Lily L. Remsing;Ana M. González;Mohammad Nur-e-Alam;M. José Fernández-Lozano

  • Biosynthesis of the Angiogenesis Inhibitor Borrelidin by Streptomyces parvulus Tü4055: Cluster Analysis and Assignment of Functions

    Carlos Olano;Barrie Wilkinson;César Sánchez;Steven J Moss

  • The role of ABC transporters in antibiotic-producing organisms: drug secretion and resistance mechanisms.

    Carmen Méndez;José A Salas

  • Engineering Deoxysugar Biosynthetic Pathways from Antibiotic-Producing Microorganisms: A Tool to Produce Novel Glycosylated Bioactive Compounds

    Leticia Rodrı́guez;Ignacio Aguirrezabalaga;Nerea Allende;Alfredo F Braña

Frequent Co-Authors

José A. Salas
José A. Salas University of Oviedo
Alfredo F. Braña
Alfredo F. Braña University of Oviedo
Jürgen Rohr
Jürgen Rohr University of Kentucky
Andreas Bechthold
Andreas Bechthold University of Freiburg
Peter F. Leadlay
Peter F. Leadlay University of Cambridge
Barrie Wilkinson
Barrie Wilkinson John Innes Centre
Wolfgang Wohlleben
Wolfgang Wohlleben University of Tübingen
C. Richard Hutchinson
C. Richard Hutchinson Bristol-Myers Squibb (Canada)
Keith F. Chater
Keith F. Chater Norwich Research Park
Nikos C. Kyrpides
Nikos C. Kyrpides Joint Genome Institute

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