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Wolfgang Wohlleben

Wolfgang Wohlleben

D-Index & Metrics

Microbiology

D-Index
67
Citations
17383
World Ranking
2258
National Ranking
165

Genetics

D-Index
63
Citations
14790
World Ranking
2886
National Ranking
202

Overview

Wolfgang Wohlleben is affiliated with the University of Tübingen in Germany. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions to Medicine. Within these broad areas, Wohlleben's work focuses on Molecular Biology, Pharmacology, Biotechnology, Oncology, and Organic Chemistry as subfields of study.

The scientist's main research topics include Microbial Natural Products and Biosynthesis, Polyamine Metabolism and Applications, Biochemical and Molecular Research, Genomics and Phylogenetic Studies, Microbial Metabolism and Applications, Peptidase Inhibition and Analysis, and Bacteriophages and microbial interactions.

Wolfgang Wohlleben has co-authored research repeatedly with a group of frequent collaborators. These include Sergii Krysenko, Andreas Kulik, Evi Stegmann, Harald Gross, and Agnieszka Mitulski.

Recent papers cover various aspects of microbiology, metabolism, and natural compounds. Notable publications include:

  • Towards the sustainable discovery and development of new antibiotics, 2021, Nature Reviews Chemistry
  • Polyamine and Ethanolamine Metabolism in Bacteria as an Important Component of Nitrogen Assimilation for Survival and Pathogenicity, 2022, Medical Sciences
  • Role of Carbon, Nitrogen, Phosphate and Sulfur Metabolism in Secondary Metabolism Precursor Supply in Streptomyces spp., 2024, Microorganisms
  • Mining Indonesian Microbial Biodiversity for Novel Natural Compounds by a Combined Genome Mining and Molecular Networking Approach, 2021, Marine Drugs
  • Poly- and Monoamine Metabolism in Streptomyces coelicolor: The New Role of Glutamine Synthetase-Like Enzymes in the Survival under Environmental Stress, 2021, Microbial Physiology

Wohlleben's work is frequently published in venues such as Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, BIOspektrum, International Journal of Molecular Sciences, Metabolic Engineering, and bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters

    Tilmann Weber;Kai Blin;Srikanth Duddela;Daniel Krug

  • Towards the sustainable discovery and development of new antibiotics

    Marcus Miethke;Marco Pieroni;Tilmann Weber;Mark Brönstrup

  • Minimum Information about a Biosynthetic Gene cluster.

    Marnix H. Medema;Marnix H. Medema;Renzo Kottmann;Pelin Yilmaz;Matthew Cummings

  • Specificity prediction of adenylation domains in nonribosomal peptide synthetases (NRPS) using transductive support vector machines (TSVMs)

    Christian Rausch;Tilmann Weber;Oliver Kohlbacher;Wolfgang Wohlleben

  • Nucleotide sequence of the phosphinothricin N-acetyltransferase gene from Streptomyces viridochromogenes Tü494 and its expression in Nicotiana tabacum.

    W. Wohlleben;Walter Arnold;I. Broer;D. Hillemann

  • Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution

    Christian Rausch;Ilka Hoof;Ilka Hoof;Tilmann Weber;Wolfgang Wohlleben

  • Phosphinothricin-resistance gene, and its use

    Eckhard Strauch;Wolfgang Dr. Wohlleben;Walter Arnold;Renate Alijah

  • Evolution of the glutamine synthetase gene, one of the oldest existing and functioning genes

    Y Kumada;D R Benson;D Hillemann;T J Hosted

  • The Streptomyces coelicolor GlnR regulon: identification of new GlnR targets and evidence for a central role of GlnR in nitrogen metabolism in actinomycetes

    Yvonne Tiffert;Petra Supra;Reinhild Wurm;Wolfgang Wohlleben

  • A vector system with temperature-sensitive replication for gene disruption and mutational cloning in streptomycetes

    G Muth;B Nussbaumer;W Wohlleben;Alfred Pühler

  • Expression of the Bacillus subtilis sacB gene leads to sucrose sensitivity in the gram-positive bacterium Corynebacterium glutamicum but not in Streptomyces lividans.

    W Jäger;A Schäfer;Alfred Pühler;G Labes

  • Identification and Analysis of the Balhimycin Biosynthetic Gene Cluster and Its Use for Manipulating Glycopeptide Biosynthesis in Amycolatopsis mediterranei DSM5908

    S. Pelzer;R. Süßmuth;D. Heckmann;J. Recktenwald

  • A bacterial hormone (the SCB1) directly controls the expression of a pathway-specific regulatory gene in the cryptic type I polyketide biosynthetic gene cluster of Streptomyces coelicolor

    Eriko Takano;Hiroshi Kinoshita;Vassilis Mersinias;Giselda Bucca

  • Crystal Structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction during Vancomycin Biosynthesis

    Katja Zerbe;Olena Pylypenko;Francesca Vitali;Weiwen Zhang

  • The roles of the nitrate reductase NarGHJI, the nitrite reductase NirBD and the response regulator GlnR in nitrate assimilation of Mycobacterium tuberculosis

    Sven Malm;Yvonne Tiffert;Julia Micklinghoff;Sonja Schultze

  • Two transcriptional regulators GlnR and GlnRII are involved in regulation of nitrogen metabolism in Streptomyces coelicolor A3(2).

    D Fink;N Weissschuh;J Reuther;W Wohlleben

  • CLUSEAN: a computer-based framework for the automated analysis of bacterial secondary metabolite biosynthetic gene clusters.

    Tilmann Weber;C. Rausch;P. Lopez;I. Hoof

  • Cloning of a phosphinothricin N-acetyltransferase gene from Streptomyces viridochromogenes Tü494 and its expression in Streptomyces lividans and Escherichia coli.

    E. Strauch;W. Wohlleben;A. Pühler

  • The dynamic architecture of the metabolic switch in Streptomyces coelicolor

    Kay Nieselt;Florian Battke;Alexander Herbig;Per Bruheim;Per Bruheim

  • On the evolution of Tn21-like multiresistance transposons: sequence analysis of the gene (aacC1) for gentamicin acetyltransferase-3-I(AAC(3)-I), another member of the Tn21-based expression cassette.

    Wolfgang Wohlleben;Walter Arnold;Luc Bissonnette;Alex Pelletier

Frequent Co-Authors

Alfred Pühler
Alfred Pühler Bielefeld University
Roderich D. Süssmuth
Roderich D. Süssmuth Technical University of Berlin
Graeme J. Nicholson
Graeme J. Nicholson University of Tübingen
Günther Jung
Günther Jung University of Tübingen
Bernhard Hauer
Bernhard Hauer University of Stuttgart
Rolf D. Schmid
Rolf D. Schmid University of Stuttgart
Sang Yup Lee
Sang Yup Lee Korea Advanced Institute of Science and Technology
Jörn Kalinowski
Jörn Kalinowski Bielefeld University
Eriko Takano
Eriko Takano University of Manchester

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