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Biology and Biochemistry

D-Index
54
Citations
13980
World Ranking
15445
National Ranking
1093

Overview

Haruo Ikeda is affiliated with Kitasato University in Japan and has contributed extensively to the field of medicine, focusing primarily on surgery, gastroenterology, and molecular biology. Their research spans several subfields including pharmacology and pulmonary and respiratory medicine.

Their work addresses a variety of topics with particular attention to gastroesophageal reflux and its treatments, esophageal and gastrointestinal pathology, and eosinophilic esophagitis. Additional research interests include microbial natural products and biosynthesis, Helicobacter pylori-related gastroenterology studies, dysphagia assessment and management, and gastric cancer management and outcomes.

Ikeda has published papers in notable journals with a recurrent presence in Digestive Endoscopy and Gastrointestinal Endoscopy. Other frequent publication venues include Endoscopy International Open, The Journal of Antibiotics, and DEN Open.

Some recent publications include:

  • Anti-reflux mucosal ablation (ARMA) as a new treatment for gastroesophageal reflux refractory to proton pump inhibitors: a pilot study, 2020, Endoscopy International Open
  • Endoscopic treatment of proton pump inhibitor-refractory gastroesophageal reflux disease with anti-reflux mucosectomy: Experience of 109 cases, 2020, Digestive Endoscopy
  • In vitro Cas9-assisted editing of modular polyketide synthase genes to produce desired natural product derivatives, 2020, Nature Communications
  • Endoscopic Classifications of Early Gastric Cancer: A Literature Review, 2021, Cancers
  • A novel endoscopic purse-string suture technique, "loop 9", for gastrointestinal defect closure: a pilot study, 2021, Endoscopy

Haruo Ikeda frequently collaborates with a set of coauthors, including:

  • Haruhiro Inoue
  • Manabu Onimaru
  • Yuto Shimamura
  • Yusuke Fujiyoshi
  • Yohei Nishikawa

Throughout their career, Ikeda's research has made contributions across multiple intersecting fields of study, with a significant publication record in surgical and gastroenterological aspects of medicine. The scientist's work is published in recognized journals, contributing to knowledge on diagnostic and therapeutic techniques in gastrointestinal medicine and related biological sciences.

Best Publications

  • Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis

    Haruo Ikeda;Jun Ishikawa;Akiharu Hanamoto;Mayumi Shinose

  • Genome sequence of an industrial microorganism Streptomyces avermitilis: Deducing the ability of producing secondary metabolites

    Satoshi Omura;Haruo Ikeda;Jun Ishikawa;Akiharu Hanamoto

  • Genomic basis for natural product biosynthetic diversity in the actinomycetes

    Markus Nett;Haruo Ikeda;Bradley S. Moore

  • Genome Sequence of the Streptomycin-Producing Microorganism Streptomyces griseus IFO 13350

    Yasuo Ohnishi;Jun Ishikawa;Hirofumi Hara;Hirokazu Suzuki

  • Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism

    Mamoru Komatsu;Takuma Uchiyama;Satoshi Omura;David E. Cane

  • Terpene synthases are widely distributed in bacteria

    Yuuki Yamada;Tomohisa Kuzuyama;Mamoru Komatsu;Kazuo Shin-ya

  • ORGANIZATION OF THE BIOSYNTHETIC GENE CLUSTER FOR THE POLYKETIDE ANTHELMINTIC MACROLIDE AVERMECTIN IN STREPTOMYCES AVERMITILIS

    Haruo Ikeda;Tomoko Nonomiya;Masayo Usami;Toshio Ohta

  • Production of 'hybrid' antibiotics by genetic engineering.

    D. A. Hopwood;F. Malpartida;H. M. Kieser;H. Ikeda

  • Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol

    Mamoru Komatsu;Muneya Tsuda;Satoshi Omura;Hideaki Oikawa

  • Engineered Streptomyces avermitilis host for heterologous expression of biosynthetic gene cluster for secondary metabolites

    Mamoru Komatsu;Kyoko Komatsu;Hanae Koiwai;Yuuki Yamada

  • Exploration and mining of the bacterial terpenome.

    David E. Cane;Haruo Ikeda

  • Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism.

    Kenji Ueda;Atsushi Yamashita;Jun Ishikawa;Masafumi Shimada

  • Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters

    Haruo Ikeda;Kazuo Shin-ya;Satoshi Omura

  • Avenolide, a Streptomyces hormone controlling antibiotic production in Streptomyces avermitilis

    Shigeru Kitani;Kiyoko T. Miyamoto;Satoshi Takamatsu;Elisa Herawati

  • Geosmin biosynthesis in Streptomyces avermitilis. Molecular cloning, expression, and mechanistic study of the germacradienol/geosmin synthase.

    David E. Cane;Xiaofei He;Seiji Kobayashi;Satoshi Omura

  • Characterization of Giant Modular PKSs Provides Insight into Genetic Mechanism for Structural Diversification of Aminopolyol Polyketides.

    Lihan Zhang;Takuya Hashimoto;Bin Qin;Junko Hashimoto

  • Biosynthesis of 2-methylisoborneol in cyanobacteria

    S. Giglio;W. K. W. Chou;H. Ikeda;D. E. Cane

  • Hyper-inducible expression system for streptomycetes

    Sachio Herai;Yoshiteru Hashimoto;Hiroki Higashibata;Hideaki Maseda

  • Cytochrome p450 complement (CYPome) of the avermectin-producer Streptomyces avermitilis and comparison to that of Streptomyces coelicolor A3(2).

    David Christopher Lamb;Haruo Ikeda;David R. Nelson;Jun Ishikawa

  • Genome mining in Streptomyces avermitilis: Cloning and characterization of SAV_76, the synthase for a new sesquiterpene, avermitilol

    Wayne K. W. Chou;Immacolata Fanizza;Takuma Uchiyama;Mamoru Komatsu

Frequent Co-Authors

Satoshi Omura
Satoshi Omura Kitasato University
Kazuo Shin-ya
Kazuo Shin-ya National Institute of Advanced Industrial Science and Technology
Takuya Nihira
Takuya Nihira Osaka University
David E. Cane
David E. Cane Brown University
Shinya Fushinobu
Shinya Fushinobu University of Tokyo
Hirofumi Shoun
Hirofumi Shoun University of Tokyo
Tomohisa Kuzuyama
Tomohisa Kuzuyama University of Tokyo
Hiroshi Tomoda
Hiroshi Tomoda Kitasato University
Masahira Hattori
Masahira Hattori Waseda University

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