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Neuroscience

D-Index
81
Citations
33313
World Ranking
1544
National Ranking
162

Research.com Recognitions

  • 1993 - Member of Academia Europaea

Overview

John Garthwaite is affiliated with University College London in the United Kingdom. Their research spans multiple fields, primarily focusing on Biochemistry, Genetics and Molecular Biology, Medicine, and Neuroscience.

The main subfields of their work include Molecular Biology, Physiology, Sensory Systems, Neurology, and Toxicology. Key topics explored in their research cover:

  • Receptor Mechanisms and Signaling
  • Olfactory and Sensory Function Studies
  • Retinal Development and Disorders
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Protein Tyrosine Phosphatases
  • Bioactive Compounds and Antitumor Agents
  • Cancer Mechanisms and Therapy

Frequent publication venues for John Garthwaite include:

  • IUPHAR/BPS Guide to Pharmacology CITE
  • British Journal of Pharmacology
  • Science Translational Medicine
  • Free Radical Biology and Medicine
  • Yearbook of pediatric endocrinology

The scientist has collaborated often with the following co-authors:

  • Annie Beuve
  • Peter Brouckaert
  • John C. Burnett
  • Andreas Friebe
  • Adrian J. Hobbs

Recent significant papers include:

  • THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors, 2021, British Journal of Pharmacology
  • The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors, 2023, British Journal of Pharmacology
  • NOS1 mutations cause hypogonadotropic hypogonadism with sensory and cognitive deficits that can be reversed in infantile mice, 2022, Science Translational Medicine
  • Receptor guanylyl cyclase (RGC) family (version 2020.3) in the IUPHAR/BPS Guide to Pharmacology Database, 2020, IUPHAR/BPS Guide to Pharmacology CITE
  • Receptor guanylyl cyclase (RGC) family in GtoPdb v.2021.3, 2021, IUPHAR/BPS Guide to Pharmacology CITE

In 1993, John Garthwaite was recognized as a Member of Academia Europaea.

Best Publications

  • Glutamate, nitric oxide and cell-cell signalling in the nervous system

    John Garthwaite

  • Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain.

    John Garthwaite;Sarah L. Charles;Russell Chess-Williams

  • Excitatory amino acid neurotoxicity and neurodegenerative disease

    Brian Meldrum;John Garthwaite

  • Nitric oxide signaling in the central nervous system.

    J Garthwaite;C L Boulton

  • Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one.

    J Garthwaite;E Southam;C L Boulton;E B Nielsen

  • NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices.

    John Garthwaite;Giti Garthwaite;Richard M.J. Palmer;Salvador Moncada

  • Concepts of neural nitric oxide‐mediated transmission

    John Garthwaite

  • Models of the diffusional spread of nitric oxide: implications for neural nitric oxide signalling and its pharmacological properties.

    J. Wood;J. Garthwaite

  • What is the real physiological NO concentration in vivo

    Catherine N. Hall;John Garthwaite

  • The nitric oxide-cyclic GMP signalling pathway in rat brain

    Eric Southam;John Garthwaite

  • NMDA receptor activation in rat hippocampus induces cyclic GMP formation through the l-arginine-nitric oxide pathway

    S.J. East;J. Garthwaite

  • Nitric oxide-dependent long-term potentiation is blocked by a specific inhibitor of soluble guanylyl cyclase.

    C.L. Boulton;E. Southam;J. Garthwaite

  • On the Role of Nitric Oxide in Hippocampal Long-Term Potentiation

    Christelle L. M. Bon;John Garthwaite

  • Interaction of the antiepileptic drug lamotrigine with recombinant rat brain type IIA Na + channels and with native Na + channels in rat hippocampal neurones

    Xinmin Xie;Barrie Lancaster;Tim Peakman;John Garthwaite

  • Excitatory amino acid receptors coupled to the nitric oxide/cyclic GMP pathway in rat cerebellum during development.

    E. Southam;S. J. East;J. Garthwaite

  • Tonic and phasic nitric oxide signals in hippocampal long-term potentiation.

    Rachel A. Hopper;John Garthwaite

  • Comparative effects of some nitric oxide donors on cyclic GMP levels in rat cerebellar slices.

    Eric Southam;John Garthwaite

  • Neurotoxicity of excitatory amino acid receptor agonists in rat cerebellar slices: Dependence on calcium concentration

    G. Garthwaite;J. Garthwaite

  • Cellular origins of cyclic GMP responses to excitatory amino acid receptor agonists in rat cerebellum in vitro.

    J Garthwaite;G Garthwaite

  • Frequency detection and temporally dispersed synaptic signal association through a metabotropic glutamate receptor pathway

    Andrew M. Batchelor;John Garthwaite

Frequent Co-Authors

Thomas Knöpfel
Thomas Knöpfel Hong Kong Baptist University
John Wood
John Wood University College London
Vincent Prevot
Vincent Prevot University of Lille
Graham L. Collingridge
Graham L. Collingridge Lunenfeld-Tanenbaum Research Institute
Kim Q. Do
Kim Q. Do University of Lausanne
Christian Hansel
Christian Hansel University of Chicago
Michel Cuenod
Michel Cuenod University of Lausanne
Beat H. Gähwiler
Beat H. Gähwiler University of Zurich
Egidio D'Angelo
Egidio D'Angelo University of Pavia

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