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Neuroscience

D-Index
79
Citations
19311
World Ranking
1708
National Ranking
24

Overview

Thomas Knöpfel is affiliated with Hong Kong Baptist University in China, focusing primarily on neuroscience. Their research spans multiple interconnected fields and subfields, including cellular and molecular neuroscience, cognitive neuroscience, biophysics, molecular biology, and clinical psychology.

The scientist's work covers a range of topics related to neural dynamics and brain function, photoreceptor and optogenetics research, advanced fluorescence microscopy techniques, neuroscience and neural engineering, neuroscience and neuropharmacology research, psychedelics and drug studies, and the influence of neurotransmitter receptors on behavior.

Recent publications illustrate the diverse scope of their research emphasis. These include:

  • Hippocampal gamma and sharp wave/ripples mediate bidirectional interactions with cortical networks during sleep (2022, Proceedings of the National Academy of Sciences)
  • Cortex-Wide Dynamics of Intrinsic Electrical Activities: Propagating Waves and Their Interactions (2021, Journal of Neuroscience)
  • Complexity of cortical wave patterns of the wake mouse cortex (2023, Nature Communications)
  • Subcellular resolution three-dimensional light-field imaging with genetically encoded voltage indicators (2020, Neurophotonics)
  • Screening and Cellular Characterization of Genetically Encoded Voltage Indicators Based on Near-Infrared Fluorescent Proteins (2020, ACS Chemical Neuroscience)

They frequently collaborate with several coauthors, such as Chenchen Song, Mianxin Liu, Changsong Zhou, Pulin Gong, and Junhao Liang. These partnerships have contributed to a significant number of publications.

Knöpfel's papers often appear in prominent venues, with multiple publications in:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • International Journal of Molecular Sciences
  • Nature Communications

Best Publications

  • Transgenic mice for intersectional targeting of neural sensors and effectors with high specificity and performance.

    Linda Madisen;Aleena R. Garner;Daisuke Shimaoka;Amy S. Chuong

  • Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex

    Takuji Iwasato;Akash Datwani;Alexander M. Wolf;Hiroshi Nishiyama

  • Metabotropic glutamate receptors: A new target for the therapy of neurodegenerative disorders?

    F. Nicoletti;V. Bruno;A. Copani;G. Casabona

  • Potassium conductances in hippocampal neurons blocked by excitatory amino-acid transmitters

    Serge Charpak;Beat H. Gähwiler;Kirn Q. Do;Thomas Knöpfel

  • Glial protein S100B modulates long-term neuronal synaptic plasticity.

    Hiroshi Nishiyama;Thomas Knöpfel;Shogo Endo;Shigeyoshi Itohara

  • Metabotropic Glutamate Receptors: Novel Targets for Drug Development

    Knöpfel T;Kuhn R;Allgeier H

  • Imaging brain electric signals with genetically targeted voltage-sensitive fluorescent proteins

    Walther Akemann;Hiroki Mutoh;Amélie Perron;Jean Rossier;Jean Rossier

  • Imaging neural circuit dynamics with a voltage-sensitive fluorescent protein

    Walther Akemann;Hiroki Mutoh;Amélie Perron;Yun Kyung Park

  • Design and characterization of a DNA-encoded, voltage-sensitive fluorescent protein.

    Rieko Sakai;Vez Repunte‐Canonigo;Christopher D. Raj;Thomas Knöpfel

  • Synaptic integration in a model of cerebellar granule cells

    F. Gabbiani;J. Midtgaard;T. Knopfel

  • Genetically encoded optical indicators for the analysis of neuronal circuits.

    Thomas Knöpfel

  • Morphological and electrophysiological properties of GABAergic and non-GABAergic cells in the deep cerebellar nuclei

    Marylka Uusisaari;Kunihiko Obata;Thomas Knöpfel

  • Engineering and Characterization of an Enhanced Fluorescent Protein Voltage Sensor

    Dimitar Dimitrov;You He;Hiroki Mutoh;Bradley J. Baker

  • Electrotonic coupling of excitable and nonexcitable cells in the heart revealed by optogenetics.

    TA Quinn;P Camelliti;EA Rog-Zielinska;U Siedlecka

  • The Second Intracellular Loop of Metabotropic Glutamate Receptor 1 Cooperates with the Other Intracellular Domains to Control Coupling to G-proteins

    Jesus Gomeza;Cecile Joly;Rainer Kuhn;Thomas Knöpfel

  • Involvement of Protein Synthesis and Degradation in Long-Term Potentiation of Schaffer Collateral CA1 Synapses

    Anna Karpova;Marina Mikhaylova;Ulrich Thomas;Thomas Knöpfel

  • Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells.

    V. Bruno;A. Copani;T. Knöpfel;R. Kuhn

  • Optical voltage imaging in neurons: moving from technology development to practical tool.

    Thomas Knöpfel;Chenchen Song

  • Voltage Imaging of Waking Mouse Cortex Reveals Emergence of Critical Neuronal Dynamics

    Gregory Scott;Erik D. Fagerholm;Hiroki Mutoh;Hiroki Mutoh;Robert Leech

  • Responses to Metabotropic Glutamate Receptor Activation in Cerebellar Purkinje Cells: Induction of an Inward Current.

    C. Staub;I. Vranesic;T. Knöpfel

  • Expression and Coupling to Polyphosphoinositide Hydrolysis of Group I Metabotropic Glutamate Receptors in Early Postnatal and Adult Rat Brain

    G. Casabona;T. Knopfel;R. Kuhn;F. Gasparini

  • Engineering and characterization of an enhanced fluorescent protein voltage sensor

    Hiroki Mutoh;Dimitar Dimitrov;You He;Walther Akemann

Frequent Co-Authors

Rainer Kuhn
Rainer Kuhn Novartis (Switzerland)
Beat H. Gähwiler
Beat H. Gähwiler University of Zurich
Pedro Grandes
Pedro Grandes University of the Basque Country
Agata Copani
Agata Copani University of Catania
Giorgio Bernardi
Giorgio Bernardi University of Rome Tor Vergata
John Garthwaite
John Garthwaite University College London
Nicola B. Mercuri
Nicola B. Mercuri University of Rome Tor Vergata
Piergiorgio Strata
Piergiorgio Strata University of Turin
Filippo Tempia
Filippo Tempia University of Turin

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