Thomas Knöpfel focuses on Neuroscience, Metabotropic glutamate receptor, Metabotropic glutamate receptor 1, Membrane potential and Metabotropic glutamate receptor 5. He merges Neuroscience with Population in his research. His Metabotropic glutamate receptor research is multidisciplinary, incorporating perspectives in Molecular biology, Cell biology and Metabotropic receptor.
The various areas that Thomas Knöpfel examines in his Metabotropic glutamate receptor 1 study include Metabotropic glutamate receptor 6, Metabotropic glutamate receptor 8, Metabotropic glutamate receptor 4 and Metabotropic glutamate receptor 7. The concepts of his Membrane potential study are interwoven with issues in Hippocampal formation, Electrophysiology, Neuron and Cell type. His biological study spans a wide range of topics, including Potassium channel and Förster resonance energy transfer.
Thomas Knöpfel spends much of his time researching Neuroscience, Metabotropic glutamate receptor, Biophysics, Membrane potential and Cell biology. The Neuroscience study combines topics in areas such as Postsynaptic potential and Neurotransmission. As a member of one scientific family, Thomas Knöpfel mostly works in the field of Metabotropic glutamate receptor, focusing on Metabotropic receptor and, on occasion, Molecular biology.
Thomas Knöpfel works mostly in the field of Biophysics, limiting it down to concerns involving Calcium and, occasionally, Endocrinology. Green fluorescent protein is closely connected to Förster resonance energy transfer in his research, which is encompassed under the umbrella topic of Membrane potential. The study incorporates disciplines such as Dendritic spine and Cell type in addition to Cell biology.
Thomas Knöpfel mostly deals with Neuroscience, Optogenetics, Voltage, Biophysics and Electrophysiology. Thomas Knöpfel performs multidisciplinary study in the fields of Neuroscience and Population via his papers. His Optogenetics research includes elements of Neuronal circuits, Cell, Cell specific and Transgene.
Thomas Knöpfel combines subjects such as Fluorescence, Förster resonance energy transfer and Paracellular transport, Permeability with his study of Biophysics. His work carried out in the field of Fluorescence brings together such families of science as Optical imaging and Biomedical engineering. His Electrophysiology study deals with In vivo intersecting with Cardiac myocyte and Pathology.
His main research concerns Neuroscience, Optogenetics, Wakefulness, Membrane potential and Nanotechnology. His research on Neuroscience often connects related areas such as Protein subunit. While the research belongs to areas of Optogenetics, he spends his time largely on the problem of Electrophysiology, intersecting his research to questions surrounding Myocyte and Ex vivo.
His Wakefulness research is multidisciplinary, relying on both Visual perception, Electroporation and Cortex. His Membrane potential research incorporates elements of Ciona intestinalis, Sensory system and Förster resonance energy transfer. His Nanotechnology research integrates issues from Cellular differentiation, Hyperpolarization, Membrane transport, Cell membrane and Cell biology.
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Transgenic mice for intersectional targeting of neural sensors and effectors with high specificity and performance.
Linda Madisen;Aleena R. Garner;Daisuke Shimaoka;Amy S. Chuong.
Metabotropic glutamate receptors: A new target for the therapy of neurodegenerative disorders?
F. Nicoletti;V. Bruno;A. Copani;G. Casabona.
Trends in Neurosciences (1996)
Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex
Takuji Iwasato;Akash Datwani;Alexander M. Wolf;Hiroshi Nishiyama.
Potassium conductances in hippocampal neurons blocked by excitatory amino-acid transmitters
Serge Charpak;Beat H. Gähwiler;Kirn Q. Do;Thomas Knöpfel.
Glial protein S100B modulates long-term neuronal synaptic plasticity.
Hiroshi Nishiyama;Thomas Knöpfel;Shogo Endo;Shigeyoshi Itohara.
Proceedings of the National Academy of Sciences of the United States of America (2002)
Metabotropic Glutamate Receptors: Novel Targets for Drug Development
Knöpfel T;Kuhn R;Allgeier H.
Journal of Medicinal Chemistry (1995)
Imaging brain electric signals with genetically targeted voltage-sensitive fluorescent proteins
Walther Akemann;Hiroki Mutoh;Amélie Perron;Jean Rossier;Jean Rossier.
Nature Methods (2010)
Design and characterization of a DNA-encoded, voltage-sensitive fluorescent protein.
Rieko Sakai;Vez Repunte‐Canonigo;Christopher D. Raj;Thomas Knöpfel.
European Journal of Neuroscience (2001)
Synaptic integration in a model of cerebellar granule cells
F. Gabbiani;J. Midtgaard;T. Knopfel.
Journal of Neurophysiology (1994)
Imaging neural circuit dynamics with a voltage-sensitive fluorescent protein
Walther Akemann;Hiroki Mutoh;Amélie Perron;Yun Kyung Park.
Journal of Neurophysiology (2012)
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