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Neuroscience

D-Index
68
Citations
14113
World Ranking
2783
National Ranking
113

Overview

Agata Copani is affiliated with the University of Catania in Italy. Their research spans several areas within medicine and biochemistry, genetics, and molecular biology, with a marked focus on physiology and molecular biology. The scientist's work also encompasses cellular and molecular neuroscience, surgery, and nutrition and dietetics.

The main topics covered in their research include:

  • Alzheimer's disease research and treatments
  • Pancreatic function and diabetes
  • Neuroscience and neuropharmacology research
  • DNA repair mechanisms
  • Mitochondrial function and pathology
  • Biochemical effects in animals
  • Photoreceptor and optogenetics research

Agata Copani's recent publications reflect diverse interests in neurodegenerative diseases and cellular response mechanisms. Notable works include:

  • β-amyloid monomers drive up neuronal aerobic glycolysis in response to energy stressors, 2021, Aging
  • Role for Metallothionein-3 in the Resistance of Human U87 Glioblastoma Cells to Temozolomide, 2020, ACS Omega
  • Molecular Connections between DNA Replication and Cell Death in β-Amyloid-Treated Neurons, 2023, Current Neuropharmacology
  • Red-Light-Photosensitized Tyrosine 10 Nitration of β-Amyloid1-42 Diverts the Protein from Forming Toxic Aggregates, 2024, ACS Chemical Neuroscience
  • Increased Heat Pain Tolerance but Hyperalgesia to Tonic Inflammatory Pain in the CRND8 Mouse Model of Alzheimer's Disease, 2023, Journal of Alzheimer s Disease

The scientist frequently collaborates with several researchers, including Rosa Santangelo, Maria Laura Giuffrida, Marianna Flora Tomasello, Ferdinando Nicoletti, and Stefania Zimbone. These coauthors have contributed to multiple joint publications, particularly in Alzheimer's disease and neuropharmacology studies.

Agata Copani's works are often published in venues such as:

  • Aging
  • Current Neuropharmacology
  • ACS Chemical Neuroscience
  • ACS Omega
  • Journal of Alzheimer s Disease

Best Publications

  • Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

    Deryk T. Loo;Agata Copani;Christian J. Pike;Edward R. Whittemore

  • Metabotropic glutamate receptors: A new target for the therapy of neurodegenerative disorders?

    F. Nicoletti;V. Bruno;A. Copani;G. Casabona

  • β-Amyloid Monomers Are Neuroprotective

    Maria Laura Giuffrida;Filippo Caraci;Bruno Pignataro;Sebastiano Cataldo

  • Induction of Dickkopf-1, a Negative Modulator of the Wnt Pathway, Is Associated with Neuronal Degeneration in Alzheimer's Brain

    Andrea Caricasole;Agata Copani;Agata Copani;Filippo Caraci;Eleonora Aronica

  • Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs.

    Valeria Bruno;Giuseppe Battaglia;Agata Copani;Mara D'Onofrio

  • Depression and Alzheimer's disease: Neurobiological links and common pharmacological targets

    Filippo Caraci;Agata Copani;Ferdinando Nicoletti;Filippo Drago

  • Neuroprotection by Glial Metabotropic Glutamate Receptors Is Mediated by Transforming Growth Factor-β

    V. Bruno;G. Battaglia;G. Casabona;A. Copani

  • Divide and die: cell cycle events as triggers of nerve cell death.

    Karl Herrup;Rachael Lee Neve;Susan Ackerman;Agata Copani

  • Mitotic signaling by β-amyloid causes neuronal death

    A. Copani;F. Condorelli;A. Caruso;C. Vancheri

  • Activation of cell-cycle-associated proteins in neuronal death: a mandatory or dispensable path?

    Agata Copani;Maria Angela Sortino;Ferdinando Nicoletti;Valeria Bruno

  • ACTIVATION OF METABOTROPIC GLUTAMATE RECEPTORS PROTECTS CULTURED NEURONS AGAINST APOPTOSIS INDUCED BY BETA -AMYLOID PEPTIDE

    A Copani;V Bruno;G Battaglia;G Leanza

  • Epigenetic modulation of mGlu2 receptors by histone deacetylase inhibitors in the treatment of inflammatory pain.

    Santina Chiechio;Magda Zammataro;Maria Elena Morales;Carla Letizia Busceti

  • Group-I metabotropic glutamate receptors: hypotheses to explain their dual role in neurotoxicity and neuroprotection

    F Nicoletti;V Bruno;M.V Catania;G Battaglia

  • Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells.

    V. Bruno;A. Copani;T. Knöpfel;R. Kuhn

  • The Wnt pathway, cell-cycle activation and β-amyloid: novel therapeutic strategies in Alzheimer's disease?

    Andrea Caricasole;Agata Copani;Alessandra Caruso;Filippo Caraci

  • Activation of Class II or III Metabotropic Glutamate Receptors Protects Cultured Cortical Neurons Against Excitotoxic Degeneration

    V. Bruno;G. Battaglia;A. Copani;R. G. Giffard

  • Expression and Coupling to Polyphosphoinositide Hydrolysis of Group I Metabotropic Glutamate Receptors in Early Postnatal and Adult Rat Brain

    G. Casabona;T. Knopfel;R. Kuhn;F. Gasparini

  • Targeting Group II Metabotropic Glutamate (mGlu) Receptors for the Treatment of Psychosis Associated with Alzheimer's Disease: Selective Activation of mGlu2 Receptors Amplifies β-Amyloid Toxicity in Cultured Neurons, Whereas Dual Activation of mGlu2 and mGlu3 Receptors Is Neuroprotective

    Filippo Caraci;Gemma Molinaro;Giuseppe Battaglia;Maria Laura Giuffrida

  • Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death.

    Valeria Bruno;Agata Copani;Giuseppe Battaglia;Rocco Raffaele

  • Beta-amyloid increases neuronal susceptibility to injury by glucose deprivation.

    Agata Copani;Jae-Young Koh;Carl W. Cotman

  • Neurobiological links between depression and AD: The role of TGF-β1 signaling as a new pharmacological target

    Filippo Caraci;Simona Federica Spampinato;Maria Grazia Morgese;Fabio Tascedda

  • Neuroprotective activity of chemokines against N-methyl-d-aspartate or β-amyloid-induced toxicity in culture

    Valeria Bruno;Agata Copani;Gilbert Besong;Giovanna Scoto

Frequent Co-Authors

Maria Angela Sortino
Maria Angela Sortino University of Catania
Pier Luigi Canonico
Pier Luigi Canonico University of Piemonte Orientale
Eleonora Aronica
Eleonora Aronica University of Amsterdam
Thomas Knöpfel
Thomas Knöpfel Hong Kong Baptist University
Robert W. Gereau
Robert W. Gereau Washington University in St. Louis
Carl W. Cotman
Carl W. Cotman University of California, Irvine
Christian J. Pike
Christian J. Pike University of Southern California
Daniela Puzzo
Daniela Puzzo University of Catania
Luigia Trabace
Luigia Trabace University of Foggia
Giorgio Cruccu
Giorgio Cruccu Sapienza University of Rome

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Related Online Degrees & Career Pathways

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Exploring these online degrees can help tailor your neuroscience expertise toward rewarding, in-demand careers across health, counseling, and therapy.

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