Rainer Kuhn

Rainer Kuhn publication distribution in Neuroscience in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Neuroscience in 2026. The highlighted bar marks where Rainer Kuhn sits on this spectrum.

Rainer Kuhn D-index placement in Neuroscience in 2026

The chart shows the D-index (discipline H-index) distribution of Neuroscience scientists ranked by Research.com in 2026. The highlighted bar marks where Rainer Kuhn sits on this spectrum.

Best Publications

• 2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist.

  Fabrizio Gasparini;Kurt Lingenhöhl;Natacha Stoehr;Peter J Flor

  859
  Citations

• The non-competitive antagonists 2-methyl-6-(phenylethynyl)pyridine and 7-hydroxyiminocyclopropan[b]chromen-1a-carboxylic acid ethyl ester interact with overlapping binding pockets in the transmembrane region of group I metabotropic glutamate receptors

  Adriana Pagano;Adriana Pagano;Doris Rüegg;Stephane Litschig;Natacha Stoehr

  393
  Citations

• C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors.

  Adriana Pagano;Giorgio Rovelli;Johannes Mosbacher;Tania Lohmann;Tania Lohmann

  377
  Citations

• Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist.

  Ewa Tatarczyńska;Aleksandra Kłodzińska;Ewa Chojnacka-Wójcik;Agnieszka Pałucha

  368
  Citations

• Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington’s disease patients

  Edward J. Wild;Roberto Boggio;Douglas Langbehn;Nicola Robertson

  305
  Citations

• mGlu5 receptors and nociceptive function II. mGlu5 receptors functionally expressed on peripheral sensory neurones mediate inflammatory hyperalgesia.

  K Walker;A Reeve;M Bowes;J Winter

  269
  Citations

• Mutagenesis and modeling of the GABAB receptor extracellular domain support a venus flytrap mechanism for ligand binding

  Thierry Galvez;Marie-Laure Parmentier;Cécile Joly;Barbara Malitschek

  253
  Citations

• Increased Seizure Susceptibility in Mice Lacking Metabotropic Glutamate Receptor 7

  Gilles Sansig;Trevor J. Bushell;Vernon R. J. Clarke;Andrei Rozov

  242
  Citations

• (-)-PHCCC, a positive allosteric modulator of mGluR4: characterization, mechanism of action, and neuroprotection.

  M. Maj;V. Bruno;Z. Dragic;R. Yamamoto

  241
  Citations

• Novel allosteric antagonists shed light on mglu(5) receptors and CNS disorders.

  Will P.J.M. Spooren;Fabrizio Gasparini;Thomas E. Salt;Rainer Kuhn

  236
  Citations

• Brain sphingosine-1-phosphate receptors: Implication for FTY720 in the treatment of multiple sclerosis

  Kumlesh K. Dev;Florian Mullershausen;Henri Mattes;Rainer R. Kuhn

  234
  Citations

• Pharmacological and endocrinological characterisation of stress-induced hyperthermia in singly housed mice using classical and candidate anxiolytics (LY314582, MPEP and NKP608).

  Will P.J.M Spooren;Philippe Schoeffter;Fabrizio Gasparini;Rainer Kuhn

  223
  Citations

• Allosteric modulators of group I metabotropic glutamate receptors: novel subtype-selective ligands and therapeutic perspectives.

  Fabrizio Gasparini;Rainer Kuhn;Jean-Philippe Pin

  217
  Citations

• The Second Intracellular Loop of Metabotropic Glutamate Receptor 1 Cooperates with the Other Intracellular Domains to Control Coupling to G-proteins

  Jesus Gomeza;Cecile Joly;Rainer Kuhn;Thomas Knöpfel

  213
  Citations

• Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells.

  V. Bruno;A. Copani;T. Knöpfel;R. Kuhn

  208
  Citations

• Metabotropic glutamate receptor subtype 5 (mGlu5) and nociceptive function. I. Selective blockade of mGlu5 receptors in models of acute, persistent and chronic pain.

  K Walker;M Bowes;M Panesar;A Davis

  205
  Citations

• The metabotropic glutamate receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) blocks fear conditioning in rats

  Brigitte Schulz;Markus Fendt;Fabrizio Gasparini;Kurt Lingenhöhl

  184
  Citations

• Expression and Coupling to Polyphosphoinositide Hydrolysis of Group I Metabotropic Glutamate Receptors in Early Postnatal and Adult Rat Brain

  G. Casabona;T. Knopfel;R. Kuhn;F. Gasparini

  176
  Citations

• Mutant huntingtin fragmentation in immune cells tracks Huntington’s disease progression

  Andreas Weiss;Ulrike Träger;Edward J. Wild;Stephan Grueninger

  176
  Citations

• The Neuroprotective Activity of Group-II Metabotropic Glutamate Receptors Requires New Protein Synthesis and Involves a Glial–Neuronal Signaling

  Valeria Bruno;Francesc X. Sureda;Marianna Storto;Giacomo Casabona

  175
  Citations

• Compartmental Localization of a Metabotropic Glutamate Receptor (mGluR7): Two Different Active Sites at a Retinal Synapse

  Johann Helmut Brandstätter;Peter Koulen;Rainer Kuhn;Herman van der Putten

  172
  Citations