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David R. Hampson

David R. Hampson

D-Index & Metrics

Neuroscience

D-Index
53
Citations
8188
World Ranking
5169
National Ranking
301

Overview

David R. Hampson is affiliated with the University of Toronto in Canada, focusing primarily on research within the fields of Biochemistry, Genetics and Molecular Biology, and Neuroscience. Their work spans several subfields including Molecular Biology, Genetics, Cognitive Neuroscience, Cellular and Molecular Neuroscience, and Neurology.

The main research topics that characterize their body of work include Genetics and Neurodevelopmental Disorders, Autism Spectrum Disorder Research, CRISPR and Genetic Engineering, Neuroscience and Neuropharmacology Research, Receptor Mechanisms and Signaling, Congenital Heart Defects Research, and Virus-based Gene Therapy Research.

Notable recent publications by David R. Hampson include:

  • Gene therapy using an ortholog of human fragile X mental retardation protein partially rescues behavioral abnormalities and EEG activity, 2021, Molecular Therapy - Methods & Clinical Development
  • Sexually dimorphic patterns in electroencephalography power spectrum and autism-related behaviors in a rat model of fragile X syndrome, 2020, Neurobiology of Disease
  • Interregulation between fragile X mental retardation protein and methyl CpG binding protein 2 in the mouse posterior cerebral cortex, 2020, Human Molecular Genetics
  • GABAergic Gene Regulatory Elements Used in Adeno-Associated Viral Vectors, 2021, Frontiers in Neurology
  • CNS-dominant human FMRP isoform rescues seizures, fear, and sleep abnormalities in Fmr1-KO mice, 2023, JCI Insight

The scientist has frequently published in venues such as Molecular Therapy - Methods & Clinical Development, IUPHAR/BPS Guide to Pharmacology CITE, Neurobiology of Disease, Frontiers in Neurology, and JCI Insight.

David R. Hampson has collaborated extensively with several coauthors including:

  • Yosuke Niibori
  • Alexander W.M. Hooper
  • Hayes Wong
  • Robert Duba-Kiss
  • Joseph T. Bruder

Best Publications

  • Glutamate Transporter Coupling to Na,K-ATPase

    Erin M. Rose;Joseph C. P. Koo;Jordan E. Antflick;Syed M. Ahmed

  • Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity

    J Ellegood;E Anagnostou;B A Babineau;J N Crawley;J N Crawley

  • Autism spectrum disorders and neuropathology of the cerebellum

    David R. Hampson;Gene J. Blatt

  • Sequence and expression of a frog brain complementary DNA encoding a kainate-binding protein

    Keiji Wada;Claude J. Dechesne;Shunichi Shimasaki;Ron G. King

  • Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor.

    Roman Pekhletski;Robert Gerlai;Linda S. Overstreet;Xi-Ping Huang

  • Phosphorylation and modulation of a Kainate receptor (GluR6) by cAMP-dependent protein kinase

    Lu-Yang Wang;Franco A. Taverna;Xi-Ping Huang;John F. MacDonald

  • Increased Seizure Susceptibility in Mice Lacking Metabotropic Glutamate Receptor 7

    Gilles Sansig;Trevor J. Bushell;Vernon R. J. Clarke;Andrei Rozov

  • The activation of glutamate receptors by kainic acid and domoic acid.

    David R. Hampson;Jerrie Lynn Manalo

  • Early developmental alterations in GABAergic protein expression in fragile X knockout mice

    Daniel C. Adusei;Laura K.K. Pacey;Duke Chen;David R. Hampson

  • Increased GABA(B) receptor-mediated signaling reduces the susceptibility of fragile X knockout mice to audiogenic seizures.

    Laura K. K. Pacey;Scott P. Heximer;David Richard Hampson

  • Cloning and characterization of a family C orphan G-protein coupled receptor.

    Donghui Kuang;Yi Yao;Janice Lam;Robert G. Tsushima

  • Interaction of domoic acid and several derivatives with kainic acid and AMPA binding sites in rat brain

    David R. Hampson;Xi-ping Huang;James W. Wells;John A. Walter

  • Modulation of Absence Seizures by the GABAA Receptor: A Critical Role for Metabotropic Glutamate Receptor 4 (mGluR4)

    O. Carter Snead;P. K. Banerjee;McIntyre Burnham;David Hampson

  • Selective Activation of mGlu4 Metabotropic Glutamate Receptors Is Protective against Excitotoxic Neuronal Death

    V. Bruno;G. Battaglia;I. Ksiazek;H. van der Putten

  • Ligand binding to the amino-terminal domain of the mGluR4 subtype of metabotropic glutamate receptor.

    Guangming Han;David R. Hampson

  • A comparison of two alternatively spliced forms of a metabotropic glutamate receptor coupled to phosphoinositide turnover

    D. S. Pickering;C. Thomsen;P. D. Suzdak;E. J. Fletcher

  • Gender-dependent effects of maternal immune activation on the behavior of mouse offspring.

    Ingrid C. Y. Xuan;David R. Hampson

  • Determination of d-serine and related neuroactive amino acids in human plasma by high-performance liquid chromatography with fluorimetric detection

    Suzanne L. Grant;Yanina Shulman;Philip Tibbo;David R. Hampson

  • Activation of Family C G-protein-coupled Receptors by the Tripeptide Glutathione *

    Minghua Wang;Yi Yao;Donghui Kuang;David Richard Hampson

  • Delayed Myelination in a Mouse Model of Fragile X Syndrome

    Laura K.K. Pacey;Ingrid C.Y. Xuan;Sihui Guan;Dafna Sussman

Frequent Co-Authors

Rainer Kuhn
Rainer Kuhn Novartis (Switzerland)
Lu-Yang Wang
Lu-Yang Wang University of Toronto
Robert Gerlai
Robert Gerlai University of Toronto
Ryuichi Shigemoto
Ryuichi Shigemoto Institute of Science and Technology Austria
Jacob Ellegood
Jacob Ellegood University of Toronto
Herman van der Putten
Herman van der Putten Novartis (Switzerland)
Jacqueline N. Crawley
Jacqueline N. Crawley University of California, Davis
Evdokia Anagnostou
Evdokia Anagnostou Holland Bloorview Kids Rehabilitation Hospital
Alea A. Mills
Alea A. Mills Cold Spring Harbor Laboratory
Daniel H. Geschwind
Daniel H. Geschwind University of California, Los Angeles

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