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Arthur D. Conigrave

Arthur D. Conigrave

D-Index & Metrics

Biology and Biochemistry

D-Index
48
Citations
7920
World Ranking
18435
National Ranking
539

Overview

Arthur D. Conigrave is affiliated with the University of Sydney in Australia. Their research spans multiple fields, predominantly within biochemistry, genetics, and molecular biology, along with a significant focus on medicine. The subfields of study they contribute to include molecular biology, physiology, cell biology, cellular and molecular neuroscience, and the endocrine and autonomic systems.

The primary topics addressed in Conigrave's research involve protein kinase regulation and GTPase signaling, erythrocyte function and pathophysiology, ion channel regulation and function, neuroscience and neuropharmacology research, regulation of appetite and obesity, cellular transport and secretion, as well as electrochemical sensors and biosensors.

Conigrave has published extensively in scientific journals, with frequent contributions to venues such as the IUPHAR/BPS Guide to Pharmacology CITE, International Journal of Molecular Sciences, Journal of the Endocrine Society, Journal of Bone and Mineral Research, and Pharmacological Reviews.

Recent publications include:

  • International Union of Basic and Clinical Pharmacology. CVIII. Calcium-Sensing Receptor Nomenclature, Pharmacology, and Function, 2020, Pharmacological Reviews
  • Symmetric activation and modulation of the human calcium-sensing receptor, 2021, Proceedings of the National Academy of Sciences
  • Toward reconciling the roles of FGF21 in protein appetite, sweet preference, and energy expenditure, 2023, Cell Reports
  • Promiscuous G-protein activation by the calcium-sensing receptor, 2024, Nature
  • Weight gain during the menopause transition: Evidence for a mechanism dependent on protein leverage, 2022, BJOG An International Journal of Obstetrics & Gynaecology

Their frequent collaborators include several researchers, notably Donald T. Ward, Katie Leach, Rebecca S. Mason, Hans Bräuner-Osborne, and Stephen J. Simpson, each having coauthored multiple works with Conigrave.

Best Publications

  • l-Amino acid sensing by the extracellular Ca2+-sensing receptor

    Arthur D. Conigrave;Stephen J. Quinn;Edward M. Brown

  • Osteoblasts play key roles in the mechanisms of action of strontium ranelate

    TC Brennan;Rybchyn;W Green;S Atwa

  • Structural mechanism of ligand activation in human calcium-sensing receptor.

    Yong Geng;Yong Geng;Lidia Mosyak;Igor Kurinov;Hao Zuo

  • Defining the Nutritional and Metabolic Context of FGF21 Using the Geometric Framework

    Samantha M. Solon-Biet;Victoria C. Cogger;Tamara Pulpitel;Marika Heblinski

  • Testing protein leverage in lean humans: A randomised controlled experimental study

    Alison K. Gosby;Arthur D. Conigrave;Namson S. Lau;Miguel A. Iglesias

  • Calcium-sensing receptor (CaSR): pharmacological properties and signaling pathways.

    Arthur D. Conigrave;Donald T. Ward

  • Phosphate acts directly on the calcium-sensing receptor to stimulate parathyroid hormone secretion.

    Patricia P. Centeno;Amanda Herberger;Hee-Chang Mun;Chialing Tu

  • Protein leverage and energy intake

    A. K. Gosby;A. D. Conigrave;D. Raubenheimer;S. J. Simpson

  • Positive and Negative Allosteric Modulators Promote Biased Signaling at the Calcium-Sensing Receptor

    Anna E Davey;Katherine Leach;Celine Valant;Arthur D Conigrave

  • Vitamin D deficiency promotes human breast cancer growth in a murine model of bone metastasis.

    Li Laine Ooi;Hong Zhou;Robert Kalak;Yu Zheng

  • Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: further evidence for metabolic compartmentation.

    Caroline Rae;Nathan Hare;William A. Bubb;Sally R. McEwan

  • Taste receptors in the gastrointestinal tract. II. L-amino acid sensing by calcium-sensing receptors: implications for GI physiology.

    Arthur D. Conigrave;Edward M. Brown

  • The gastrointestinal tract as a nutrient-balancing organ.

    Fiona J. Clissold;Benjamin J. Tedder;Arthur D. Conigrave;Stephen J. Simpson

  • An Akt-dependent Increase in Canonical Wnt Signaling and a Decrease in Sclerostin Protein Levels Are Involved in Strontium Ranelate-induced Osteogenic Effects in Human Osteoblasts *

    Mark S. Rybchyn;Michael Slater;Arthur D. Conigrave;Rebecca S. Mason

  • L-amino acid sensing by the calcium-sensing receptor: a general mechanism for coupling protein and calcium metabolism?

    Arthur Conigrave;Alison Franks;Edward M Brown;Stephen J Quinn

  • Protein kinase C phosphorylates the carboxyl terminus of the plasma membrane Ca(2+)-ATPase from human erythrocytes.

    K. K. W. Wang;L. C. Wright;C. L. Machan;B. G. Allen

  • Allosteric Modulation of the Calcium-sensing Receptor by γ-Glutamyl Peptides INHIBITION OF PTH SECRETION, SUPPRESSION OF INTRACELLULAR cAMP LEVELS, AND A COMMON MECHANISM OF ACTION WITH l-AMINO ACIDS

    Geoffrey K. Broadhead;Hee-chang Mun;Vimesh A. Avlani;Orane Jourdon

  • Three adjacent serines in the extracellular domains of the CaR are required for L-amino acid-mediated potentiation of receptor function.

    Zaixiang Zhang;Weiying Qiu;Stephen J. Quinn;Arthur D. Conigrave

  • Dietary protein and bone health: roles of amino acid-sensing receptors in the control of calcium metabolism and bone homeostasis

    A. D. Conigrave;E. M. Brown;René Rizzoli

  • L-amino acids regulate parathyroid hormone secretion.

    Arthur D. Conigrave;Hee-Chang Mun;Leigh Delbridge;Stephen J. Quinn

Frequent Co-Authors

Edward M. Brown
Edward M. Brown University of Rochester Medical Center
Arthur Christopoulos
Arthur Christopoulos Monash University
Stephen J. Simpson
Stephen J. Simpson University of Sydney
David Raubenheimer
David Raubenheimer University of Sydney
Basil D. Roufogalis
Basil D. Roufogalis University of Sydney
Philip W. Kuchel
Philip W. Kuchel University of Sydney
Patrick M. Sexton
Patrick M. Sexton Monash University
Markus J. Seibel
Markus J. Seibel University of Sydney
Hans Bräuner-Osborne
Hans Bräuner-Osborne University of Copenhagen
David R. Hampson
David R. Hampson University of Toronto

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