John F. MacDonald

Best Publications

• Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels.

  Zhi-Gang Xiong;Xiao-Man Zhu;Xiang-Ping Chu;Manabu Minami

  1273
  Citations

• Activation of Synaptic NMDA Receptors Induces Membrane Insertion of New AMPA Receptors and LTP in Cultured Hippocampal Neurons

  Wei-Yang Lu;Heng-Ye Man;William Ju;William S. Trimble

  1142
  Citations

• Specific Coupling of NMDA Receptor Activation to Nitric Oxide Neurotoxicity by PSD-95 Protein

  Rita Sattler;Zhigang Xiong;Wei Yang Lu;Mathias Hafner

  1080
  Citations

• A key role for TRPM7 channels in anoxic neuronal death

  Michelle Aarts;Koji Iihara;Wen Li Wei;Zhi Gang Xiong

  928
  Citations

• Abnormal Spine Morphology and Enhanced LTP in LIMK-1 Knockout Mice

  Yanghong Meng;Yu Zhang;Vitali Tregoubov;Christopher Janus

  818
  Citations

• Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by α5 subunit-containing γ-aminobutyric acid type A receptors

  Valerie B. Caraiscos;Erin M. Elliott;Kong E. You-Ten;Victor Y. Cheng

  677
  Citations

• Recruitment of functional GABA A receptors to postsynaptic domains by insulin

  Q. Wan;Z. G. Xiong;H. Y. Man;C. A. Ackerley

  630
  Citations

• Enhanced LTP in Mice Deficient in the AMPA Receptor GluR2

  Zhengping Jia;Nadia Agopyan;Peter Miu;Zhigang Xiong

  603
  Citations

• Use-dependent block of excitatory amino acid currents in cultured neurons by ketamine.

  J. F. MacDonald;Z. Miljkovic;P. Pennefather

  535
  Citations

• G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors.

  W Y Lu;Z G Xiong;S Lei;B A Orser

  481
  Citations

• Regulation of kainate receptors by cAMP-dependent protein kinase and phosphatases.

  Lu-Yang Wang;M. W. Salter;J. F. Macdonald

  473
  Citations

• Distinct functional and pharmacological properties of tonic and quantal inhibitory postsynaptic currents mediated by gamma-aminobutyric acid(A) receptors in hippocampal neurons.

  Donglin Bai;Guoyun Zhu;Peter Pennefather;Michael F. Jackson

  466
  Citations

• Multiple mechanisms of ketamine blockade of N-methyl-D-aspartate receptors.

  Beverley A. Orser;Peter S. Pennefather;John F. MacDonald

  463
  Citations

• Activation of PI3-kinase is required for AMPA receptor insertion during LTP of mEPSCs in cultured hippocampal neurons

  Heng-Ye Man;Qinhua Wang;Wei-Yang Lu;William Ju

  448
  Citations

• Activation of Pannexin-1 Hemichannels Augments Aberrant Bursting in the Hippocampus

  Roger J. Thompson;Michael F. Jackson;Michelle E. Olah;Ravi L. Rungta

  422
  Citations

• Ketamine and phencyclidine cause a voltage-dependent block of responses to L-aspartic acid.

  C.R. Honey;Z. Miljkovic;J.F. Macdonald

  380
  Citations

• CAKβ/Pyk2 Kinase Is a Signaling Link for Induction of Long-Term Potentiation in CA1 Hippocampus

  Yue-Qiao Huang;Wei-Yang Lu;Declan W Ali;Kenneth A Pelkey

  333
  Citations

• Actions of ketamine, phencyclidine and MK-801 on NMDA receptor currents in cultured mouse hippocampal neurones.

  J F MacDonald;M C Bartlett;I Mody;P Pahapill

  326
  Citations

• Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia.

  Hong-Shuo Sun;Michael F Jackson;Michael F Jackson;Loren J Martin;Karen Jansen

  317
  Citations

• Inhibition by propofol (2,6 di-isopropylphenol) of the N-methyl-D-aspartate subtype of glutamate receptor in cultured hippocampal neurones.

  Beverley A. Orser;Maria Bertlik;Maria Bertlik;Lu-Yang Wang;John F. MacDonald

  317
  Citations