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Neuroscience

D-Index
38
Citations
7605
World Ranking
8491
National Ranking
496

Overview

Lu-Yang Wang is affiliated with the University of Toronto in Canada. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Medicine, and Neuroscience, reflecting a multidisciplinary approach to biological and medical sciences.

The scientist's subfields of study include Molecular Biology, Cellular and Molecular Neuroscience, Neurology, Parasitology, and Cognitive Neuroscience. These areas indicate a focus on the molecular mechanisms underlying neurological functions and disorders, as well as interactions between molecular biology and parasitology.

Key topics in Lu-Yang Wang's work cover a range of subjects within neuroscience and molecular biology. These include Neuroscience and Neuropharmacology Research, Ion channel regulation and function, Neuroinflammation and Neurodegeneration Mechanisms, RNA modifications and cancer, Biosensors and Analytical Detection, Ferroptosis and cancer prognosis, and Memory and Neural Mechanisms.

They have published extensively, with recent papers that illustrate their active research pursuits:

  • FTH promotes the proliferation and renders the HCC cells specifically resist to ferroptosis by maintaining iron homeostasis, 2021, Cancer Cell International
  • Inhibition of CISD2 promotes ferroptosis through ferritinophagy-mediated ferritin turnover and regulation of p62-Keap1-NRF2 pathway, 2022, Cellular & Molecular Biology Letters
  • Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains, 2022, Nature Communications
  • Insular cortical circuits as an executive gateway to decipher threat or extinction memory via distinct subcortical pathways, 2022, Nature Communications
  • High-resolution electron cryomicroscopy of V-ATPase in native synaptic vesicles, 2024, Science

Lu-Yang Wang collaborates frequently with several researchers, reflecting a team-oriented approach in their projects. Notable co-authors include Ádám Fekete, Tian-Le Xu, Haibo Shi, Yanchun Li, and Yan-Jiao Wu, each contributing to multiple joint publications.

The scientist often publishes in well-regarded venues, with a significant number of publications appearing in bioRxiv (Cold Spring Harbor Laboratory), The Journal of Physiology, Neuron, Journal of Neuroscience, and Cell Reports. These journals underscore the focus on physiology, cellular neuroscience, and molecular biology within their research portfolio.

Best Publications

  • High-frequency firing helps replenish the readily releasable pool of synaptic vesicles

    Lu-Yang Wang;Lu-Yang Wang;Leonard K. Kaczmarek

  • hSK4, a member of a novel subfamily of calcium-activated potassium channels.

    William J. Joiner;Lu-Yang Wang;Michael D. Tang;Leonard K. Kaczmarek

  • Regulation of kainate receptors by cAMP-dependent protein kinase and phosphatases.

    Lu-Yang Wang;M. W. Salter;J. F. Macdonald

  • Contribution of the Kv3.1 potassium channel to high‐frequency firing in mouse auditory neurones

    Lu-Yang Wang;Li Gan;Ian D. Forsythe;Leonard K. Kaczmarek

  • A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression.

    Xin Chen;Siyi Wanggou;Ankur Bodalia;Min Zhu

  • Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation

    Brian Tsang;Brian Tsang;Jason Arsenault;Jason Arsenault;Robert M. Vernon;Hong Lin

  • Developmental Transformation of the Release Modality at the Calyx of Held Synapse

    Michael J. Fedchyshyn;Lu-Yang Wang

  • Inhibition by propofol (2,6 di-isopropylphenol) of the N-methyl-D-aspartate subtype of glutamate receptor in cultured hippocampal neurones.

    Beverley A. Orser;Maria Bertlik;Maria Bertlik;Lu-Yang Wang;John F. MacDonald

  • Propofol modulates activation and desensitization of GABAA receptors in cultured murine hippocampal neurons.

    Beverley A. Orser;Lu-Yang Wang;Peter S. Pennefather;John F. MacDonald

  • Regulation of NMDA receptors in cultured hippocampal neurons by protein phosphatases 1 and 2A

    Lu-Yang Wang;Bev A. Orser;David L. Brautigan;John F. MacDonald

  • Phosphorylation and modulation of a Kainate receptor (GluR6) by cAMP-dependent protein kinase

    Lu-Yang Wang;Franco A. Taverna;Xi-Ping Huang;John F. MacDonald

  • Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunits.

    William J. Joiner;Michael D. Tang;Lu-Yang Wang;Steven I. Dworetzky

  • Developmental profiles of glutamate receptors and synaptic transmission at a single synapse in the mouse auditory brainstem.

    Indu Joshi;Lu-Yang Wang

  • Synaptic Vesicles in Mature Calyx of Held Synapses Sense Higher Nanodomain Calcium Concentrations during Action Potential-Evoked Glutamate Release

    Lu-Yang Wang;Erwin Neher;Holger Taschenberger

  • Modulation of the kv3.1b potassium channel isoform adjusts the fidelity of the firing pattern of auditory neurons.

    Carolyn M. Macica;Christian A. A. von Hehn;Lu-Yang Wang;Chi-Shun Ho

  • Septins Regulate Developmental Switching from Microdomain to Nanodomain Coupling of Ca2+ Influx to Neurotransmitter Release at a Central Synapse

    Yi Mei Yang;Michael J. Fedchyshyn;Giovanbattista Grande;Jamila Aitoubah

  • Electrophysiological and pharmacological characterization of a mammalian Shaw channel expressed in NIH 3T3 fibroblasts

    T. Kanemasa;L. Gan;T. M. Perney;L. Y. Wang

  • Modulation of AMPA/kainate receptors in cultured murine hippocampal neurones by protein kinase C.

    Lu-Yang Wang;E. M. Dudek;M. D. Browning;J. F. Macdonald

  • Amplitude and kinetics of action potential-evoked Ca2+ current and its efficacy in triggering transmitter release at the developing calyx of Held synapse.

    Yi Mei Yang;Lu Yang Wang

  • Regulation of N-methyl-D-aspartate receptor function by constitutively active protein kinase C.

    Zhi-Gang Xiong;Ramin Raouf;Wei-Yang Lu;Lu-Yang Wang

Frequent Co-Authors

David R. Hampson
David R. Hampson University of Toronto
Zhuan Zhou
Zhuan Zhou Peking University
Beverley A. Orser
Beverley A. Orser University of Toronto
Michael W. Salter
Michael W. Salter University of Toronto
Michael Browning
Michael Browning University of Oxford
James H. Eubanks
James H. Eubanks University Health Network
Jacob Ellegood
Jacob Ellegood University of Toronto
Jack R. Mellor
Jack R. Mellor University of Bristol
David J. A. Wyllie
David J. A. Wyllie University of Edinburgh
Ying Wu
Ying Wu Northwestern University

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