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Takeshi Sakaba

Takeshi Sakaba

D-Index & Metrics

Neuroscience

D-Index
32
Citations
6878
World Ranking
9492
National Ranking
355

Overview

Takeshi Sakaba is affiliated with Doshisha University in Japan and conducts research primarily in the fields of neuroscience and biochemistry, genetics, and molecular biology. Their scholarly work focuses on cellular and molecular neuroscience, molecular biology, cognitive neuroscience, cell biology, and physiology.

The scientist's research covers main topics including neuroscience and neuropharmacology research, photoreceptor and optogenetics research, cellular transport and secretion, lipid membrane structure and behavior, neural dynamics and brain function, neuroscience and neural engineering, and retinal development and disorders.

Frequent publication venues for Sakaba's work include the Proceedings of the National Academy of Sciences, eLife, Cell Reports, bioRxiv (Cold Spring Harbor Laboratory), and Science Advances.

Selected recent papers authored or co-authored by Takeshi Sakaba include:

  • "Direct imaging of rapid tethering of synaptic vesicles accompanying exocytosis at a fast central synapse" (2020, Proceedings of the National Academy of Sciences)
  • "Rapid Ca 2+ channel accumulation contributes to cAMP-mediated increase in transmission at hippocampal mossy fiber synapses" (2021, Proceedings of the National Academy of Sciences)
  • "Intersectin-Mediated Clearance of SNARE Complexes Is Required for Fast Neurotransmission" (2020, Cell Reports)
  • "Increased vesicle fusion competence underlies long-term potentiation at hippocampal mossy fiber synapses" (2023, Science Advances)
  • "Excitatory selective LTP of supramammillary glutamatergic/GABAergic cotransmission potentiates dentate granule cell firing" (2022, Proceedings of the National Academy of Sciences)

Some frequent co-authors of Takeshi Sakaba are Himawari Hirai, Yuki Hashimotodani, Kenzo Hirose, Hirokazu Sakamoto, and Rinako Miyano.

Best Publications

  • Multiple roles of calcium ions in the regulation of neurotransmitter release.

    Erwin Neher;Takeshi Sakaba

  • Calmodulin mediates rapid recruitment of fast-releasing synaptic vesicles at a calyx-type synapse.

    Takeshi Sakaba;Erwin Neher

  • Vesicle pools and short-term synaptic depression: lessons from a large synapse

    Ralf Schneggenburger;Takeshi Sakaba;Erwin Neher

  • Direct modulation of synaptic vesicle priming by GABA B receptor activation at a glutamatergic synapse

    Takeshi Sakaba;Erwin Neher

  • Calcium dependence of exo- and endocytotic coupling at a glutamatergic synapse.

    Nobutake Hosoi;Matthew Holt;Takeshi Sakaba

  • The coupling between synaptic vesicles and Ca2+ channels determines fast neurotransmitter release

    Kristian Wadel;Erwin Neher;Takeshi Sakaba

  • Quantitative relationship between transmitter release and calcium current at the calyx of held synapse.

    Takeshi Sakaba;Erwin Neher

  • Combining Deconvolution and Noise Analysis for the Estimation of Transmitter Release Rates at the Calyx of Held

    Erwin Neher;Takeshi Sakaba

  • Quantitative analysis of calcium-dependent vesicle recruitment and its functional role at the calyx of held synapse

    Nobutake Hosoi;Takeshi Sakaba;Erwin Neher

  • Submillisecond Kinetics of Glutamate Release from a Sensory Synapse

    Henrique von Gersdorff;Takeshi Sakaba;Ken Berglund;Masao Tachibana

  • Involvement of Actin Polymerization in Vesicle Recruitment at the Calyx of Held Synapse

    Takeshi Sakaba;Erwin Neher

  • Roles of the fast-releasing and the slowly releasing vesicles in synaptic transmission at the calyx of held

    Takeshi Sakaba

  • Dynamic Control of Synaptic Vesicle Replenishment and Short-Term Plasticity by Ca2+-Calmodulin-Munc13-1 Signaling

    Noa Lipstein;Takeshi Sakaba;Benjamin H. Cooper;Kun-Han Lin

  • Preferential potentiation of fast-releasing synaptic vesicles by cAMP at the calyx of Held

    Takeshi Sakaba;Erwin Neher

  • Two Ca2+-Dependent Steps Controlling Synaptic Vesicle Fusion and Replenishment at the Cerebellar Basket Cell Terminal

    Takeshi Sakaba

  • Estimation of quantal parameters at the calyx of Held synapse.

    Takeshi Sakaba;Ralf Schneggenburger;Erwin Neher

  • Target-Dependent Feedforward Inhibition Mediated by Short-Term Synaptic Plasticity in the Cerebellum

    Jin Bao;Kerstin Reim;Takeshi Sakaba

  • Control of Inhibitory Synaptic Outputs by Low Excitability of Axon Terminals Revealed by Direct Recording

    Shin-ya Kawaguchi;Takeshi Sakaba

  • Estimating Transmitter Release Rates from Postsynaptic Current Fluctuations

    Erwin Neher;Takeshi Sakaba

  • Two components of transmitter release in retinal bipolar cells: exocytosis and mobilization of synaptic vesicles.

    Takeshi Sakaba;Masao Tachibana;Ko Matsui;Naotoshi Minami

  • Kinetics of Releasable Synaptic Vesicles and Their Plastic Changes at Hippocampal Mossy Fiber Synapses

    Mitsuharu Midorikawa;Takeshi Sakaba

  • Ca2+-activated K+ current at presynaptic terminals of goldfish retinal bipolar cells

    Takeshi Sakaba;Hiroshi Ishikane;Masao Tachibana

  • Readily releasable pool of synaptic vesicles measured at single synaptic contacts

    Federico F. Trigo;Takeshi Sakaba;Takeshi Sakaba;David Ogden;Alain Marty

  • KV10.1 opposes activity‐dependent increase in Ca2+ influx into the presynaptic terminal of the parallel fibre–Purkinje cell synapse

    Lena Sünke Mortensen;Hartmut Schmidt;Zohreh Farsi;Alonso Barrantes‐Freer

  • Direct imaging of rapid tethering of synaptic vesicles accompanying exocytosis at a fast central synapse.

    Takafumi Miki;Mitsuharu Midorikawa;Takeshi Sakaba

  • Rapid Ca2+ channel accumulation contributes to cAMP-mediated increase in transmission at hippocampal mossy fiber synapses

    Ryota Fukaya;Marta Maglione;Marta Maglione;Stephan J. Sigrist;Stephan J. Sigrist;Takeshi Sakaba

Frequent Co-Authors

Nils Brose
Nils Brose Max Planck Society
Ralf Schneggenburger
Ralf Schneggenburger École Polytechnique Fédérale de Lausanne
Stephan J. Sigrist
Stephan J. Sigrist Freie Universität Berlin
Jens Eilers
Jens Eilers Leipzig University
Ilan Lampl
Ilan Lampl Weizmann Institute of Science
Henrique von Gersdorff
Henrique von Gersdorff Oregon Health & Science University
Dietmar Schmitz
Dietmar Schmitz Charité - University Medicine Berlin
Alain Marty
Alain Marty Université Paris Cité

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