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87
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28103
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Overview

Tomoyuki Takahashi is a researcher affiliated with the Okinawa Institute of Science and Technology in Japan. Their work spans multiple fields including Biochemistry, Genetics and Molecular Biology, and Medicine, with a focus on several subfields such as Molecular Biology, Cellular and Molecular Neuroscience, Cell Biology, Genetics, and Neurology.

Their research covers a range of topics involving cellular transport and secretion, neuroscience and neuropharmacology research, lipid membrane structure and behavior, photoreceptor and optogenetics research, genetics and neurodevelopmental disorders, as well as neuroinflammation and neurodegeneration mechanisms, including Alzheimer's disease research and treatments.

Tomoyuki Takahashi has contributed to numerous scientific publications across prominent venues. The most frequent publication outlets include:

  • Proceedings of the National Academy of Sciences
  • Journal of Neuroscience
  • eLife
  • bioRxiv (Cold Spring Harbor Laboratory)
  • SSRN Electronic Journal

Prominent recent papers authored by Takahashi include:

  • "Hidden proteome of synaptic vesicles in the mammalian brain" (2020) - Proceedings of the National Academy of Sciences
  • "Frequency-Dependent Block of Excitatory Neurotransmission by Isoflurane via Dual Presynaptic Mechanisms" (2020) - Journal of Neuroscience
  • "Suppression of Vps13 adaptor protein mutants reveals a central role for PI4P in regulating prospore membrane extension" (2021) - PLoS Genetics
  • "Green fluorescent cAMP indicator of high speed and specificity suitable for neuronal live-cell imaging" (2022) - Proceedings of the National Academy of Sciences
  • "Anoxia-induced hippocampal LTP is regeneratively produced by glutamate and nitric oxide from the neuro-glial-endothelial axis" (2024) - iScience

Their research collaborations include frequent co-authorship with the following scientists:

  • Han-Ying Wang
  • Yushiro Yamashita
  • Kotaro Yuge
  • Toyojiro Matsuishi
  • Yoshiki Kuwabara

Best Publications

  • The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43

    Ikuo Kimura;Kentaro Ozawa;Daisuke Inoue;Takeshi Imamura

  • A thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system.

    Francis A. Edwards;Arthur Konnerth;Bert Sakmann;Tomoyuki Takahashi

  • Molecular distinction between fetal and adult forms of muscle acetylcholine receptor

    Masayoshi Mishina;Toshiyuki Takai;Keiji Imoto;Masaharu Noda

  • Different types of calcium channels mediate central synaptic transmission

    Tomoyuki Takahashi;Akiko Momiyama

  • Expression of functional sodium channels from cloned cDNA

    Masaharu Noda;Takayuki Ikeda;Harukazu Suzuki;Hiroshi Takeshima

  • Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor ε2 subunit mutant mice

    Tatsuya Kutsuwada;Kenji Sakimura;Toshiya Manabe;Chitoshi Takayama

  • Patch clamp measurements on Xenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels.

    Christoph Methfessel;Veit Witzemann;Tomoyuki Takahashi;Masayoshi Mishina

  • Inactivation of Presynaptic Calcium Current Contributes to Synaptic Depression at a Fast Central Synapse

    Ian D Forsythe;Tetsuhiro Tsujimoto;Margaret Barnes-Davies;Matthew F Cuttle

  • Location of functional regions of acetylcholine receptor α-subunit by site-directed mutagenesis

    Masayoshi Mishina;Takamasa Tobimatsu;Keiji Imoto;Ken Ichi Tanaka

  • Regional distribution of substance P in the spinal cord and nerve roots of the cat and the effect of dorsal root section.

    Tomoyuki Takahashi;Masanori Otsuka

  • Presynaptic calcium current modulation by a metabotropic glutamate receptor.

    Tomoyuki Takahashi;Ian D. Forsythe;Tetsuhiro Tsujimoto;Margaret Barnes-Davies

  • A blue-light-activated adenylyl cyclase mediates photoavoidance in Euglena gracilis

    Unknown

  • Expression of functional acetylcholine receptor from cloned cDNAs

    Masayoshi Mishina;Tomohiro Kurosaki;Takamasa Tobimatsu;Yuuki Morimoto

  • Role of a metabotropic glutamate receptor in synaptic modulation in the accessory olfactory bulb

    Yasunori Hayashi;Akiko Momiyama;Tomoyuki Takahashi;Tomoyuki Takahashi;Hitoshi Ohishi

  • Facilitation of long-term potentiation and memory in mice lacking nociceptin receptors

    Toshiya Manabe;Yukihiro Noda;Takayoshi Mamiya;Hiroyuki Katagiri

  • Impairment of hippocampal mossy fiber LTD in mice lacking mGluR2.

    Mineto Yokoi;Katsunori Kobayashi;Toshiya Manabe;Tomoyuki Takahashi

  • NMDA-receptor channel diversity in the developing cerebellum

    Mark Farrant;Dirk Feldmeyer;Tomoyuki Takahashi;Stuart G. Cull-Candy

  • Functional correlation of fetal and adult forms of glycine receptors with developmental changes in inhibitory synaptic receptor channels.

    Tomoyuki Takahashi;Akiko Momiyama;Keiko Hirai;Fumio Hishinuma

  • Developmental Changes in Calcium Channel Types Mediating Central Synaptic Transmission

    Shinichi Iwasaki;Akiko Momiyama;Osvaldo D. Uchitel;Tomoyuki Takahashi

  • Molecular determinants differentiating photocurrent properties of two channelrhodopsins from chlamydomonas.

    Hongxia Wang;Yuka Sugiyama;Takuya Hikima;Eriko Sugano

  • Role of acetylcholine receptor subunits in gating of the channel.

    Bert Sakmann;Christoph Methfessel;Masayoshi Mishina;Tomoyuki Takahashi;Tomoyuki Takahashi

  • G-Protein-Coupled Modulation of Presynaptic Calcium Currents and Transmitter Release by a GABAB Receptor

    Tomoyuki Takahashi;Yoshinao Kajikawa;Tetsuhiro Tsujimoto

Frequent Co-Authors

Toshiya Manabe
Toshiya Manabe University of Tokyo
Masayoshi Mishina
Masayoshi Mishina Ritsumeikan University
Masanori Otsuka
Masanori Otsuka Tokyo Medical and Dental University
Ian D. Forsythe
Ian D. Forsythe University of Leicester
Masahiko Watanabe
Masahiko Watanabe Hokkaido University
Yoshiro Inoue
Yoshiro Inoue Hokkaido University
Ryuichi Shigemoto
Ryuichi Shigemoto Institute of Science and Technology Austria
Stuart G. Cull-Candy
Stuart G. Cull-Candy University College London
Fabrizio Eusebi
Fabrizio Eusebi Sapienza University of Rome
Keiji Imoto
Keiji Imoto National Institute for Physiological Sciences

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