His primary scientific interests are in Sodium channel, Biophysics, Biochemistry, Cell biology and Gating. His research in Sodium channel intersects with topics in Voltage-gated ion channel, Neuroscience, Depolarization and Pharmacology. Todd Scheuer is interested in Membrane potential, which is a branch of Biophysics.
His work carried out in the field of Cell biology brings together such families of science as Endocrinology and Internal medicine. The study incorporates disciplines such as Ion channel, Potassium channel and Ion transporter in addition to Gating. As a part of the same scientific study, Todd Scheuer usually deals with the G alpha subunit, concentrating on Transmembrane domain and frequently concerns with Stereochemistry.
Todd Scheuer mainly focuses on Sodium channel, Biophysics, Biochemistry, Cell biology and Gating. His Sodium channel research includes elements of Extracellular, Stereochemistry, Intracellular, Ion channel and Transmembrane domain. His Biophysics study combines topics in areas such as Protein structure and Receptor, Transmembrane protein.
In his study, which falls under the umbrella issue of Biochemistry, N-type calcium channel is strongly linked to R-type calcium channel. His Cell biology research includes themes of Internal medicine and Voltage-dependent calcium channel. Todd Scheuer interconnects Potassium channel, Voltage clamp, Helix, Analytical chemistry and Patch clamp in the investigation of issues within Gating.
His scientific interests lie mostly in Biophysics, Sodium channel, Neuroscience, Voltage-dependent calcium channel and Synaptic plasticity. His research in Biophysics intersects with topics in Voltage-gated ion channel, Wild type and Extracellular, Biochemistry. His Sodium channel research incorporates elements of Electrophysiology, Rheobase, Gating, Transmembrane protein and Intracellular.
His Gating study incorporates themes from Protein structure, Crystallography and Ion channel. The study incorporates disciplines such as Haploinsufficiency and Neurotransmission in addition to Neuroscience. His Voltage-dependent calcium channel study combines topics from a wide range of disciplines, such as Binding site and Cell biology.
Todd Scheuer mostly deals with Neuroscience, Biophysics, Sodium channel, Dravet syndrome and Voltage-dependent calcium channel. His study in Neuroscience is interdisciplinary in nature, drawing from both Haploinsufficiency and Neurotransmission. Todd Scheuer is involved in the study of Biophysics that focuses on Gating in particular.
His Gating research includes elements of Ionic bonding, Drug receptor and Ion channel. His biological study spans a wide range of topics, including Parvalbumin and Rheobase. Within one scientific family, Todd Scheuer focuses on topics pertaining to Binding site under Voltage-dependent calcium channel, and may sometimes address concerns connected to Inorganic chemistry and Dihydropyridine.
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The crystal structure of a voltage-gated sodium channel
Jian Payandeh;Todd Scheuer;Ning Zheng;William A. Catterall.
Nature (2011)
Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy
Frank H Yu;Massimo Mantegazza;Ruth E Westenbroek;Carol A Robbins.
Nature Neuroscience (2006)
Modulation of Ca2+ channels by G-protein beta gamma subunits.
Stefan Herlitze;David E. Garcia;David E. Garcia;Ken Mackie;Bertil Hille.
Nature (1996)
Molecular determinants of state-dependent block of Na+ channels by local anesthetics
David S. Ragsdale;Jancy C. McPhee;Todd Scheuer;William A. Catterall.
Science (1994)
A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation
J W West;D E Patton;T Scheuer;Y Wang.
Proceedings of the National Academy of Sciences of the United States of America (1992)
Voltage-gated ion channels and gating modifier toxins
William A. Catterall;Sandrine Cestèle;Vladimir Yarov-Yarovoy;Frank H. Yu.
Toxicon (2007)
Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels.
David S. Ragsdale;Jancy C. McPhee;Todd Scheuer;William A. Catterall.
Proceedings of the National Academy of Sciences of the United States of America (1996)
Structure and function of the β2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif
L.L. Isom;D.S. Ragsdale;K.S. De Jongh;R.E. Westenbroek.
Cell (1995)
Molecular Determinants of High Affinity Binding of α-Scorpion Toxin and Sea Anemone Toxin in the S3-S4 Extracellular Loop in Domain IV of the Na+ Channel α Subunit
John C. Rogers;Yusheng Qu;Timothy N. Tanada;Todd Scheuer.
Journal of Biological Chemistry (1996)
Crystal structure of a voltage-gated sodium channel in two potentially inactivated states
Jian Payandeh;Tamer M. Gamal El-Din;Todd Scheuer;Ning Zheng.
Nature (2012)
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