Ruth E. Westenbroek

Best Publications

• Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy

  Frank H Yu;Massimo Mantegazza;Ruth E Westenbroek;Carol A Robbins

  1286
  Citations

• The endocannabinoid system controls key epileptogenic circuits in the hippocampus.

  Krisztina Monory;Federico Massa;Federico Massa;Michaela Egertová;Matthias Eder

  835
  Citations

• Biochemical properties and subcellular distribution of an N-type calcium hannel α1 subunit

  Ruth E. Westenbroek;Johannes W. Hell;Concepcion Warner;Stefan J. Dubel

  718
  Citations

• Clustering of L-type Ca2+ channels at the base of major dendrites in hippocampal pyramidal neurons.

  Ruth E. Westenbroek;Michael K. Ahlijanian;William A. Catterall

  713
  Citations

• Autistic-like behaviour in Scn1a +/− mice and rescue by enhanced GABA-mediated neurotransmission

  Sung Han;Chao Tai;Ruth E. Westenbroek;Frank H. Yu;Frank H. Yu

  689
  Citations

• Differential subcellular localization of the RI and RII Na+ channel subtypes in central neurons.

  Ruth E. Westenbroek;Dawn K. Merrick;William A. Catterall

  622
  Citations

• Sodium Channel β4, a New Disulfide-Linked Auxiliary Subunit with Similarity to β2

  Frank H. Yu;Ruth E. Westenbroek;Inmaculada Silos-Santiago;Kimberly A. McCormick

  565
  Citations

• Localization of Ca2+ Channel Subtypes on Rat Spinal Motor Neurons, Interneurons, and Nerve Terminals

  Ruth E. Westenbroek;Linda Hoskins;William A. Catterall

  559
  Citations

• Calcium Channel Types with Distinct Presynaptic Localization Couple Differentially to Transmitter Release in Single Calyx-Type Synapses

  Ling Gang Wu;Ruth E. Westenbroek;J. Gerard G Borst;William A. Catterall

  492
  Citations

• Cannabidiol attenuates seizures and social deficits in a mouse model of Dravet syndrome.

  Joshua S. Kaplan;Nephi Stella;William A. Catterall;Ruth E. Westenbroek

  439
  Citations

• Subunit structure and localization of dihydropyridine-sensitive calcium channels in mammalian brain, spinal cord, and retina.

  Michael K. Ahlijanian;Ruth E. Westenbroek;William A. Catterall

  419
  Citations

• An unexpected role for brain-type sodium channels in coupling of cell surface depolarization to contraction in the heart

  Sebastian K. G. Maier;Ruth E. Westenbroek;Kenneth A. Schenkman;Eric O. Feigl

  418
  Citations

• Sudden unexpected death in a mouse model of Dravet syndrome

  Franck Kalume;Ruth E. Westenbroek;Christine S. Cheah;Frank H. Yu

  362
  Citations

• Reduced Sodium Current in Purkinje Neurons from NaV1.1 Mutant Mice: Implications for Ataxia in Severe Myoclonic Epilepsy in Infancy

  Franck Kalume;Frank H. Yu;Ruth E. Westenbroek;Todd Scheuer

  361
  Citations

• Distinct Subcellular Localization of Different Sodium Channel α and β Subunits in Single Ventricular Myocytes From Mouse Heart

  Sebastian K.G. Maier;Ruth E. Westenbroek;Kimberly A. McCormick;Rory Curtis

  346
  Citations

• Specific deletion of NaV1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome

  Christine S. Cheah;Frank H. Yu;Ruth E. Westenbroek;Franck K. Kalume

  332
  Citations

• Mice Lacking Sodium Channel β1 Subunits Display Defects in Neuronal Excitability, Sodium Channel Expression, and Nodal Architecture

  Chunling Chen;Ruth E. Westenbroek;Xiaorong Xu;Chris A. Edwards

  323
  Citations

• Structural basis for gating charge movement in the voltage sensor of a sodium channel

  Vladimir Yarov-Yarovoy;Paul G. DeCaen;Paul G. DeCaen;Ruth E. Westenbroek;Chien Yuan Pan;Chien Yuan Pan

  289
  Citations

• Transfer of glycogen-derived lactate from astrocytes to axons via specific monocarboxylate transporters supports mouse optic nerve activity.

  Selva Baltan Tekkök;Angus M. Brown;Angus M. Brown;Ruth Westenbroek;Luc Pellerin

  284
  Citations

• Impaired excitability of somatostatin- and parvalbumin-expressing cortical interneurons in a mouse model of Dravet syndrome.

  Chao Tai;Yasuyuki Abe;Ruth E. Westenbroek;Todd Scheuer

  284
  Citations