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Genetics and Molecular Biology
UK
2024

D-Index & Metrics

Molecular Biology

D-Index
121
Citations
66732
World Ranking
247
National Ranking
18

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in United Kingdom Leader Award

Overview

Paul Nurse is affiliated with The Francis Crick Institute in the United Kingdom. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, with significant work in Molecular Biology, Cell Biology, Oncology, Pharmacology, and Plant Science.

Their recent research output includes several publications in prominent scientific journals. Notable papers are:

  • Core control principles of the eukaryotic cell cycle, 2022, Nature
  • Biology must generate ideas as well as data, 2021, Nature
  • CDK control pathways integrate cell size and ploidy information to control cell division, 2021, eLife
  • The Hydrophobic Patch Directs Cyclin B to Centrosomes to Promote Global CDK Phosphorylation at Mitosis, 2020, Current Biology
  • The cell cycle and cell size influence the rates of global cellular translation and transcription in fission yeast, 2023, The EMBO Journal

They collaborate frequently with several co-authors, including:

  • Souradeep Basu
  • Andrew W. Jones
  • Paul Rees
  • Nitin Kapadia
  • Tania Auchynnikava

Paul Nurse publishes regularly in a variety of scientific venues, with multiple contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • The EMBO Journal
  • Journal of Cell Science
  • Open Biology

Their research covers a range of topics including:

  • Microtubule and mitosis dynamics
  • Fungal and yeast genetics research
  • Gene Regulatory Network Analysis
  • Cancer-related Molecular Pathways
  • DNA Repair Mechanisms
  • Bioinformatics and Genomic Networks
  • Genomics and Chromatin Dynamics

Best Publications

  • Universal control mechanism regulating onset of M-phase

    Paul Nurse

  • Molecular genetic analysis of fission yeast Schizosaccharomyces pombe.

    Sergio Moreno;Amar Klar;Paul Nurse

  • The genome sequence of Schizosaccharomyces pombe

    V. Wood;R. Gwilliam;M.A. Rajandream;M. Lyne

  • ANIMAL CELL CYCLES AND THEIR CONTROL

    Chris Norbury;Paul Nurse

  • Tyrosine phosphorylation of the fission yeast cdc2 + protein kinase regulates entry into mitosis

    Kathleen L. Gould;Paul Nurse

  • Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2

    Melanie G. Lee;Paul Nurse

  • cdc25+ functions as an inducer in the mitotic control of fission yeast.

    Paul Russell;Paul Nurse

  • Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog

    Paul Russell;Paul Nurse

  • Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe

    Paul Nurse;Paul Nurse;Pierre Thuriaux;Pierre Thuriaux;Kim Nasmyth;Kim Nasmyth

  • Genetic control of cell size at cell division in yeast

    Paul Nurse

  • Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+.

    Jean Gautier;Chris Norbury;Manfred Lohka;Paul Nurse

  • Gene required in G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeast.

    Paul Nurse;Paul Nurse;Yvonne Bissett;Yvonne Bissett

  • Ordering S phase and M phase in the cell cycle

    Paul Nurse

  • A Long Twentieth Century of the Cell Cycle and Beyond

    Paul Nurse

  • Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe

    Dong Uk Kim;Jacqueline Hayles;Dongsup Kim;Valerie Wood;Valerie Wood

  • Regulation of p34cdc2 protein kinase during mitosis.

    Sergio Moreno;Jacqueline Hayles;Paul Nurse

  • Phosphorylation at Thr167 is required for Schizosaccharomyces pombe P34cdc2 function

    K.L. Gould;S. Moreno;D.J. Owen;S. Sazer

  • Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates.

    C Norbury;J Blow;P Nurse

  • Cohesin Rec8 is required for reductional chromosome segregation at meiosis.

    Yoshinori Watanabe;Paul Nurse

  • The Cdt1 protein is required to license DNA for replication in fission yeast.

    Hideo Nishitani;Zoi Lygerou;Takeharu Nishimoto;Paul Nurse

Frequent Co-Authors

Sergio Moreno
Sergio Moreno University of Salamanca
Kathleen L. Gould
Kathleen L. Gould Vanderbilt University
Susan L. Forsburg
Susan L. Forsburg University of Southern California
Chris J. Norbury
Chris J. Norbury University of Oxford
Jürg Bähler
Jürg Bähler University College London
Paul Russell
Paul Russell Scripps Research Institute
Ambrosius P. Snijders
Ambrosius P. Snijders The Francis Crick Institute
Bart Barrell
Bart Barrell Wellcome Sanger Institute
Michael A. Quail
Michael A. Quail Wellcome Sanger Institute
Hans Lehrach
Hans Lehrach Max Planck Society

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