World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
45
Citations
10154
World Ranking
19063
National Ranking
1483

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Iain M. Hagan is affiliated with the University of Manchester in the United Kingdom. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these areas, their work focuses on subfields such as Molecular Biology, Cell Biology, Pulmonary and Respiratory Medicine, Oncology, and Ecology, Evolution, Behavior and Systematics.

The scientist's research topics include microtubule and mitosis dynamics, advanced breast cancer therapies, cancer-related molecular pathways, fungal and yeast genetics research, PI3K/AKT/mTOR signaling in cancer, fungal plant pathogen control, and metabolism related to diabetes and cancer.

They have published multiple papers in well-known venues, with frequent publications in:

  • Open Biology (3 papers)
  • bioRxiv (Cold Spring Harbor Laboratory) (2 papers)
  • Methods in molecular biology (1 paper)

Notable recent publications include:

  • "Release from cell cycle arrest with Cdk4/6 inhibitors generates highly synchronized cell cycle progression in human cell culture" (2020, Open Biology)
  • "A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans" (2021, Open Biology)
  • "Elevated basal AMP-activated protein kinase activity sensitizes colorectal cancer cells to growth inhibition by metformin" (2023, Open Biology)
  • "Highly Synchronous Mitotic Progression in Schizosaccharomyces pombe Upon Relief of Transient Cdc2-asM17 Inhibition" (2021, Methods in molecular biology)
  • "Release from cell cycle arrest with Cdk4/6 inhibitors generates highly synchronised cell cycle progression in human cell culture" (2020, bioRxiv [Cold Spring Harbor Laboratory])

Frequent co-authors collaborating with Iain M. Hagan include:

  • Eleanor W. Trotter
  • Lenka Hálová
  • Tingting Wang
  • Kaitlin R. Morrison
  • Janni Petersen

Their work intersects multiple research topics highlighting both fundamental and applied aspects of molecular biology in human health and fungal genetics.

The scientist has been recognized as a Member of the European Molecular Biology Organization (EMBO), reflecting their involvement in broader scientific communities.

Best Publications

  • Cell cycle-dependent specific positioning and clustering of centromeres and telomeres in fission yeast.

    H Funabiki;I Hagan;S Uzawa;M Yanagida

  • Polo-like kinases: a team that plays throughout mitosis

    David M. Glover;Iain M. Hagan;Álvaro A.M. Tavares

  • The use of cell division cycle mutants to investigate the control of microtubule distribution in the fission yeast Schizosaccharomyces pombe

    I.M. Hagan;J.S. Hyams

  • The conserved Schizosaccharomyces pombe kinase plo1, required to form a bipolar spindle, the actin ring, and septum, can drive septum formation in G1 and G2 cells.

    Hiroyuki Ohkura;Iain M. Hagan;David M. Glover

  • The product of the spindle formation gene sad1+ associates with the fission yeast spindle pole body and is essential for viability.

    I Hagan;M Yanagida

  • Novel potential mitotic motor protein encoded by the fission yeast cut7 + gene

    Iain Hagan;Mitsuhiro Yanagida

  • Kinesin-related cut7 protein associates with mitotic and meiotic spindles in fission yeast.

    Iain Hagan;Mitsuhiro Yanagida

  • Mal3, the Fission Yeast Homologue of the Human APC-interacting Protein EB-1 Is Required for Microtubule Integrity and the Maintenance of Cell Form

    Jens D. Beinhauer;Iain M. Hagan;Johannes H. Hegemann;Ursula Fleig

  • Cloning and sequencing of the cyclin-related cdc13+ gene and a cytological study of its role in fission yeast mitosis.

    I. Hagan;J. Hayles;P. Nurse

  • VECTORS FOR THE EXPRESSION OF TAGGED PROTEINS IN SCHIZOSACCHAROMYCES POMBE

    Rachel A Craven;Dominic J.F Griffiths;Katherine S Sheldrick;Richard E Randall

  • Multiple Reaction Monitoring to Identify Sites of Protein Phosphorylation with High Sensitivity

    Richard D. Unwin;John R. Griffiths;Michael K. Leverentz;Agnes Grallert

  • Growth polarity and cytokinesis in fission yeast: the role of the cytoskeleton.

    John Marks;Iain M. Hagan;Jeremy S. Hyams

  • The fission yeast microtubule cytoskeleton

    I.M. Hagan

  • The Centrosome and Its Duplication Cycle

    Jingyan Fu;Iain M. Hagan;David M. Glover

  • Asymmetric segregation on spindle poles of the Schizosaccharomyces pombe septum-inducing protein kinase Cdc7p

    Marc Sohrmann;Susanne Schmidt;Iain Hagan;Viesturs Simanis

  • The centrosomal kinase Nek2 displays elevated levels of protein expression in human breast cancer.

    Daniel G. Hayward;Robert B. Clarke;Alison J. Faragher;Meenu R. Pillai

  • FH3, A Domain Found in Formins, Targets the Fission Yeast Formin Fus1 to the Projection Tip During Conjugation

    Janni Petersen;Olaf Nielsen;Richard Egel;Iain M. Hagan

  • A PP1-PP2A phosphatase relay controls mitotic progression.

    Agnes Grallert;Elvan Boke;Anja Hagting;Ben Hodgson

  • The COP9/signalosome complex is conserved in fission yeast and has a role in S phase.

    Kirsten E. Mundt;Joanne Porte;Johanne M. Murray;Constantinos Brikos

  • Plo1 kinase recruitment to the spindle pole body and its role in cell division in Schizosaccharomyces pombe.

    Daniel P. Mulvihill;Janni Petersen;Hiroyuki Ohkura;David M. Glover

Frequent Co-Authors

Viesturs Simanis
Viesturs Simanis École Polytechnique Fédérale de Lausanne
David M. Glover
David M. Glover California Institute of Technology
Mitsuhiro Yanagida
Mitsuhiro Yanagida Okinawa Institute of Science and Technology
Alan Bridge
Alan Bridge Swiss Institute of Bioinformatics
Antony M. Carr
Antony M. Carr University of Sussex
Boris Macek
Boris Macek University of Tübingen
John R. Griffiths
John R. Griffiths University of Manchester
Jonathon Pines
Jonathon Pines Institute of Cancer Research
Richard E. Randall
Richard E. Randall University of St Andrews
Kay Hofmann
Kay Hofmann University of Cologne

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