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Microbiology

D-Index
64
Citations
18746
World Ranking
2581
National Ranking
224

Overview

Richard E. Randall is affiliated with the University of St Andrews in the United Kingdom. Their research primarily spans the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Within these broader areas, their work focuses on Immunology, Epidemiology, Molecular Biology, Infectious Diseases, and Oncology.

The main topics of Dr. Randall's research include:

  • Viral Infections and Vectors
  • interferon and immune responses
  • Virology and Viral Diseases
  • Inflammasome and immune disorders
  • Cytokine Signaling Pathways and Interactions
  • Respiratory viral infections research
  • Vector-Borne Animal Diseases

Their recent papers illustrate a sustained focus on antiviral immunity and interferon signaling mechanisms. Key publications include:

  • "Genetic Lesions of Type I Interferon Signalling in Human Antiviral Immunity" (2020), published in Trends in Genetics
  • "Partial human Janus kinase 1 deficiency predominantly impairs responses to interferon gamma and intracellular control of mycobacteria" (2022), published in Frontiers in Immunology
  • "Direct Antiviral Activity of IFN-Stimulated Genes Is Responsible for Resistance to Paramyxoviruses in ISG15-Deficient Cells" (2020), published in The Journal of Immunology
  • "Innate Intracellular Antiviral Responses Restrict the Amplification of Defective Virus Genomes of Parainfluenza Virus 5" (2020), published in Journal of Virology
  • "The Timing and Magnitude of the Type I Interferon Response Are Correlated with Disease Tolerance in Arbovirus Infection" (2023), published in mBio

Richard E. Randall's frequent co-authors include:

  • D. F. Young
  • David J. Hughes
  • Andri Vasou
  • Stephen Goodbourn
  • J. Andrejeva

Their publications are often found in the following venues, highlighting a recurring presence in virology and immunology journals:

  • Journal of General Virology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Trends in Genetics
  • Frontiers in Immunology
  • Journal of Virology

Best Publications

  • Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures.

    Richard E. Randall;Stephen Goodbourn

  • Interferons: cell signalling, immune modulation, antiviral response and virus countermeasures.

    S. Goodbourn;L. Didcock;R. E. Randall

  • The multifunctional NS1 protein of influenza A viruses.

    Benjamin Geoffrey Hale;Richard Edward Randall;J Ortin;David Jackson

  • The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-β promoter

    J. Andrejeva;K. S. Childs;D. F. Young;T. S. Carlos

  • The V protein of simian virus 5 inhibits interferon signalling by targeting STAT1 for proteasome-mediated degradation.

    L. Didcock;D. F. Young;S. Goodbourn;R. E. Randall

  • Taxonomy of the order Mononegavirales: update 2016

    Claudio L. Afonso;Gaya K. Amarasinghe;Krisztián Bányai;Yīmíng Bào

  • mda-5, but not RIG-I, is a common target for paramyxovirus V proteins.

    Kay Childs;Nicola Stock;Craig Ross;Jelena Andrejeva

  • Inhibition of Interferon Signaling by the New York 99 Strain and Kunjin Subtype of West Nile Virus Involves Blockage of STAT1 and STAT2 Activation by Nonstructural Proteins

    Wen Jun Liu;Xiang Ju Wang;Xiang Ju Wang;Vladislav V. Mokhonov;Vladislav V. Mokhonov;Pei Yong Shi

  • Influenza A virus NS1 protein binds p85β and activates phosphatidylinositol-3-kinase signaling

    Benjamin G. Hale;David Jackson;Yun Hsiang Chen;Robert A. Lamb

  • The NPro Product of Bovine Viral Diarrhea Virus Inhibits DNA Binding by Interferon Regulatory Factor 3 and Targets It for Proteasomal Degradation

    Louise Hilton;Kartykayan Moganeradj;Gang Zhang;Yun-Hsiang Chen

  • Taxonomy of the order Mononegavirales: update 2017

    Gaya K. Amarasinghe;Yīmíng Bào;Christopher F. Basler;Sina Bavari

  • Identification of an epitope on the P and V proteins of simian virus 5 that distinguishes between two isolates with different biological characteristics

    J. A. Southern;D. F. Young;F. Heaney;W. K. Baumgärtner

  • Recovery of Paramyxovirus Simian Virus 5 with a V Protein Lacking the Conserved Cysteine-rich Domain: The Multifunctional V Protein Blocks both Interferon-β Induction and Interferon Signaling

    Biao He;Reay G. Paterson;Nicola Stock;Joan E. Durbin

  • VECTORS FOR THE EXPRESSION OF TAGGED PROTEINS IN SCHIZOSACCHAROMYCES POMBE

    Rachel A Craven;Dominic J.F Griffiths;Katherine S Sheldrick;Richard E Randall

  • Paramyxoviridae Use Distinct Virus-Specific Mechanisms to Circumvent the Interferon Response

    D.F. Young;L. Didcock;S. Goodbourn;R.E. Randall

  • Bunyamwera Bunyavirus Nonstructural Protein NSs Counteracts the Induction of Alpha/Beta Interferon

    Friedemann Weber;Anne Bridgen;John K. Fazakerley;Hein Streitenfeld

  • STAT2 deficiency and susceptibility to viral illness in humans

    Sophie Hambleton;Stephen Goodbourn;Dan F. Young;Paul Dickinson

  • Degradation of STAT1 and STAT2 by the V Proteins of Simian Virus 5 and Human Parainfluenza Virus Type 2, Respectively: Consequences for Virus Replication in the Presence of Alpha/Beta and Gamma Interferons

    J. Andrejeva;D. F. Young;S. Goodbourn;R. E. Randall

  • Influenza virus activation of the interferon system.

    Marian J. Killip;Marian J. Killip;Ervin Fodor;Richard E. Randall

  • Innate sensing of HIV-infected cells.

    Alice Lepelley;Stephanie Louis;Marion Sourisseau;Helen K. W. Law

  • The V Proteins of Simian Virus 5 and Other Paramyxoviruses Inhibit Induction of Interferon-β

    Emma Poole;Biao He;Robert A. Lamb;Richard E. Randall

Frequent Co-Authors

Robert A. Lamb
Robert A. Lamb Northwestern University
Sophie Hambleton
Sophie Hambleton Newcastle University
Tomáš Hanke
Tomáš Hanke University of Oxford
Richard M. Elliott
Richard M. Elliott University of Glasgow
Andrew J. Davison
Andrew J. Davison University of Glasgow
Lin-Fa Wang
Lin-Fa Wang Duke NUS Graduate Medical School
Andrew J. Cant
Andrew J. Cant Newcastle University
John McLauchlan
John McLauchlan University of Glasgow
Juan Ortín
Juan Ortín Spanish National Research Council
Norbert Nowotny
Norbert Nowotny University of Veterinary Medicine Vienna

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