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Microbiology

D-Index
67
Citations
14552
World Ranking
2290
National Ranking
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Overview

Juan Ortín is a researcher affiliated with the Spanish National Research Council in Spain. Their work primarily focuses on biochemistry, genetics, molecular biology, immunology, and microbiology, reflecting a multidisciplinary approach to understanding complex biological processes.

The main fields of study in Ortín's research include:

  • Biochemistry, Genetics and Molecular Biology
  • Immunology and Microbiology

These fields are complemented by subfields in:

  • Molecular Biology
  • Immunology

Ortín's research spans several key topics, notably:

  • Interferon and immune responses
  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer

Among their recent scientific contributions is a publication titled Structural insights into influenza A virus ribonucleoproteins reveal a processive helical track as transcription mechanism, published in 2020 in Nature Microbiology. This study reflects an integration of molecular biology and virology techniques to analyze viral components involved in transcription.

Ortín collaborates frequently with several co-authors, including:

  • Rocío Coloma
  • Rocío Arranz
  • J.M. de la Rosa-Trevín
  • Carlos Óscar S. Sorzano
  • Sandie Munier

Their publications have appeared primarily in the journal Nature Microbiology, indicating a focus on research relevant to microbial systems and their molecular mechanisms.

Best Publications

  • The multifunctional NS1 protein of influenza A viruses.

    Benjamin Geoffrey Hale;Richard Edward Randall;J Ortin;David Jackson

  • The quasispecies (extremely heterogeneous) nature of viral RNA genome populations: biological relevance — a review

    Esteban Domingo;Encarnación Martínez-Salas;Francisco Sobrino;Juan Carlos de la Torre

  • The Structural Basis for CAP Binding by Influenza Virus Polymerase Subunit Pb2.

    Delphine Guilligay;Franck Tarendeau;Patricia Resa-Infante;Rocío Coloma

  • Influenza virus NS1 protein inhibits pre-mRNA splicing and blocks mRNA nucleocytoplasmic transport.

    P Fortes;A Beloso;J Ortín

  • Lack of transmission of H5N1 avian–human reassortant influenza viruses in a ferret model

    Taronna R. Maines;Li-Mei Chen;Yumiko Matsuoka;Hualan Chen

  • Multiple genetic variants arise in the course of replication of foot-and-mouth disease virus in cell culture.

    Francisco Sobrino;Mercedes Dávila;Juan Ortín;Esteban Domingo

  • The Structure of Native Influenza Virion Ribonucleoproteins

    Rocío Arranz;Rocío Coloma;Rocío Coloma;Francisco Javier Chichón;José Javier Conesa

  • The mammalian Staufen protein localizes to the somatodendritic domain of cultured hippocampal neurons: Implications for its involvement in mRNA transport

    Michael A. Kiebler;Indradeo Hemraj;Paul Verkade;Martin Köhrmann

  • Eukaryotic Translation Initiation Factor 4GI Is a Cellular Target for NS1 Protein, a Translational Activator of Influenza Virus

    Tomás Aragón;Susana de la Luna;Isabel Novoa;Luis Carrasco

  • The structure of a biologically active influenza virus ribonucleoprotein complex

    Rocío Coloma;José M. Valpuesta;Rocío Arranz;José L. Carrascosa

  • Influenza virus NS1 protein enhances the rate of translation initiation of viral mRNAs.

    S de la Luna;P Fortes;A Beloso;J Ortín

  • The influenza virus RNA synthesis machine: advances in its structure and function.

    Patricia Resa-Infante;Núria Jorba;Rocio Coloma;Juan Ortin

  • Expression in mammalian cells of a gene from Streptomyces alboniger conferring puromycin resistance

    Jesùs A. Vara;Agustìn Portela;Juan Ortìn;Antonio Jimènez

  • PABP1 and eIF4GI associate with influenza virus NS1 protein in viral mRNA translation initiation complexes.

    Idoia Burgui;Tomás Aragón;Juan Ortín;Amelia Nieto

  • A Human Sequence Homologue of Staufen Is an RNA-Binding Protein That Is Associated with Polysomes and Localizes to the Rough Endoplasmic Reticulum

    Rosa María Marión;Puri Fortes;Ana Beloso;Carlos Dotti

  • Open reading frame 5 of porcine reproductive and respiratory syndrome virus as a cause of virus-induced apoptosis.

    P Suárez;M Díaz-Guerra;C Prieto;M Esteban

  • The composition of Staufen‐containing RNA granules from human cells indicates their role in the regulated transport and translation of messenger RNAs

    Patricia Villacé;Rosa M. Marión;Juan Ortín

  • 3D structure of the influenza virus polymerase complex: Localization of subunit domains

    Estela Area;Jaime Martín-Benito;Pablo Gastaminza;Eva Torreira

  • Genetic trans-complementation establishes a new model for influenza virus RNA transcription and replication.

    Núria Jorba;Rocío Coloma;Juan Ortín

  • Ultrastructural and Functional Analyses of Recombinant Influenza Virus Ribonucleoproteins Suggest Dimerization of Nucleoprotein during Virus Amplification

    Joaquín Ortega;Jaime Martín-Benito;Thomas Zürcher;José M. Valpuesta

Frequent Co-Authors

Juan Valcárcel
Juan Valcárcel Institució Catalana de Recerca i Estudis Avançats
Esteban Domingo
Esteban Domingo Centro de Biología Molecular Severo Ochoa
José L. Carrascosa
José L. Carrascosa Spanish National Research Council
José A. Melero
José A. Melero Instituto de Salud Carlos III
José M. Valpuesta
José M. Valpuesta Spanish National Research Council
Richard E. Randall
Richard E. Randall University of St Andrews
Francisco Sobrino
Francisco Sobrino Spanish National Research Council
José A. Bengoechea
José A. Bengoechea Queen's University Belfast
Eladio Viñuela
Eladio Viñuela Spanish National Research Council
Oscar Llorca
Oscar Llorca Spanish National Research Council

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