Dennis Y. Loh

Overview

Best Publications

• Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

  Kenneth M. Murphy;Amy B. Heimberger;Dennis Y. Loh

  2139
  Citations

• Mice Lacking p27Kip1 Display Increased Body Size, Multiple Organ Hyperplasia, Retinal Dysplasia, and Pituitary Tumors

  Keiko Nakayama;Keiko Nakayama;Noriko Ishida;Michiko Shirane;Akira Inomata

  1918
  Citations

• Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

  Noboru Motoyama;Fanping Wang;Kevin A. Roth;Hirofumi Sawa

  1525
  Citations

• Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo.

  Elizabeth R. Kearney;Kathryn A. Pape;Dennis Y. Loh;Marc K. Jenkins

  1180
  Citations

• Positive and negative selection of an antigen receptor on T cells in transgenic mice

  William C. Sha;Christopher A. Nelson;Rodney D. Newberry;David M. Kranz

  934
  Citations

• Essential role for ZAP-70 in both positive and negative selection of thymocytes

  Izumi Negishi;Izumi Negishi;Izumi Negishi;Noboru Motoyama;Kei Ichi Nakayama;Kei Ichi Nakayama;Kei Ichi Nakayama;Keiko Nakayama;Keiko Nakayama;Keiko Nakayama

  667
  Citations

• Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice.

  W C Sha;C A Nelson;R D Newberry;D M Kranz

  612
  Citations

• Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia

  K Nakayama;I Negishi;K Kuida;H Sawa

  523
  Citations

• Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice.

  Kei Ichi Nakayama;Keiko Nakayama;Izumi Negishi;Keisuke Kuida

  514
  Citations

• Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes

  Yoichi Shinkai;Shigeo Koyasu;Kei Ichi Nakayama;Kenneth M. Murphy

  506
  Citations

• The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development

  John D. Alvarez;Dag H. Yasui;Hiroyuki Niida;Tadashi Joh

  501
  Citations

• Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4.

  Elizabeth R. Kearney;Theresa L. Walunas;Robert W. Karr;Phillip A. Morton

  429
  Citations

• Murine T-cell receptor mutants with deletions of beta-chain variable region genes

  Mark A. Behlke;Hubert S. Chou;Konrad Huppi;Dennis Y. Loh

  418
  Citations

• Receptor-stimulated death pathway is opened by antigen in mature T cells.

  John H. Russell;Christine L. White;Dennis Y. Loh;Patricia Meleedy-Rey

  332
  Citations

• T-cell receptor beta-chain expression: dependence on relatively few variable region genes

  Mark A. Behlke;Dominic G. Spinella;Hubert S. Chou;William Sha

  226
  Citations

• The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling

  Alec M. Cheng;Izumi Negishi;Steven J. Anderson;Andrew C. Chan

  224
  Citations

• Positive selection of transgenic receptor-bearing thymocytes by Kb antigen is altered by Kb mutations that involve peptide binding.

  William C. Sha;Christopher A. Nelson;Rodney D. Newberry;Jeffrey K. Pullen

  220
  Citations

• The level of CD8 expression can determine the outcome of thymic selection

  Ellen A. Robey;Fred Ramsdell;Dimitris Kioussis;William Sha

  187
  Citations

• Molecular basis of a mouse strain-specific anti-hapten response

  Dennis Y. Loh;Alfred L.M. Bothwell;Mary E. White-Scharf;Thereza Imanishi-Kari

  176
  Citations

• Requirement for CD8 β Chain in Positive Selection of CD8-Lineage T Cells

  Kei Ichi Nakayama;Keiko Nakayama;Izumi Negishi;Keisuke Kuida

  148
  Citations