World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
86
Citations
30602
World Ranking
2935
National Ranking
215

Research.com Recognitions

  • 2016 - Fellow of the Royal Society, United Kingdom

Overview

Jonathon Pines is affiliated with the Institute of Cancer Research in the United Kingdom and has contributed extensively to the field of Biochemistry, Genetics, and Molecular Biology, with a particular focus on Molecular Biology, Cell Biology, and Biophysics.

Their research encompasses diverse topics including Microtubule and mitosis dynamics, Genomics and Chromatin Dynamics, Advanced Fluorescence Microscopy Techniques, Gene Regulatory Network Analysis, CRISPR and Genetic Engineering, Epigenetics and DNA Methylation, and Advanced Proteomics Techniques and Applications.

They have published work in multiple scientific venues. The most frequent publication outlets include:

  • Open Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Seminars in Cell and Developmental Biology
  • The Journal of Cell Biology
  • The EMBO Journal

Among their recent papers are:

  • Spindle assembly checkpoint activation and silencing at kinetochores, 2021, Seminars in Cell and Developmental Biology
  • Cyclin B1-Cdk1 facilitates MAD1 release from the nuclear pore to ensure a robust spindle checkpoint, 2020, The Journal of Cell Biology
  • Cell cycle-dependent binding between Cyclin B1 and Cdk1 revealed by time-resolved fluorescence correlation spectroscopy, 2022, Open Biology
  • Image integrity and standards, 2020, Open Biology
  • Spatial control of the APC/C ensures the rapid degradation of cyclin B1, 2024, The EMBO Journal

Pines has collaborated frequently with several researchers. Notable co-authors include:

  • Luca Cirillo
  • Catherine Coates
  • Jyoti S. Choudhary
  • Sapthaswaran Veerapathiran
  • Theodoros I. Roumeliotis

In recognition of contributions to science, Pines was awarded the status of Fellow of the Royal Society in the United Kingdom in 2016.

Best Publications

  • Cyclins and cancer II: Cyclin D and CDK inhibitors come of age

    Tony Hunter;Jonathan Pines

  • Isolation of a human cyclin cDNA: Evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2

    Jonathon Pines;Tony Hunter

  • Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport

    J. Pines;T. Hunter

  • Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B

    Jonathon Pines;Tony Hunter

  • Progressive Activation of CyclinB1-Cdk1 Coordinates Entry to Mitosis

    Olivier Gavet;Jonathon Pines

  • Temporal and spatial control of cyclin B1 destruction in metaphase.

    Paul Clute;Jonathon Pines

  • Cyclins and cyclin-dependent kinases: a biochemical view

    J Pines

  • Active cyclin B1–Cdk1 first appears on centrosomes in prophase

    Mark Jackman;Catherine Lindon;Erich A. Nigg;Jonathon Pines

  • Cyclins and cancer

    Tony Hunter;Jonathon Pines

  • Cyclins and cyclin-dependent kinases: take your partners

    Jonathan Pines

  • Mitotic regulation of the human anaphase-promoting complex by phosphorylation.

    Claudine Kraft;Franz Herzog;Christian Gieffers;Karl Mechtler

  • Four-dimensional control of the cell cycle.

    Jonathon Pines

  • Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins

    Ivan Ahel;Dragana Ahel;Takahiro Matsusaka;Allison J. Clark

  • MPF localization is controlled by nuclear export

    Anja Hagting;Christina Karlsson;Paul Clute;Mark Jackman

  • Ordered proteolysis in anaphase inactivates Plk1 to contribute to proper mitotic exit in human cells.

    Catherine Lindon;Jonathon Pines

  • Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A

    Maria Mudryj;Stephen H. Devoto;Scott W. Hiebert;Tony Hunter

  • Cyclin a Is Destroyed in Prometaphase and Can Delay Chromosome Alignment and Anaphase

    Nicole den Elzen;Jonathon Pines

  • Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1

    Anja Hagting;Nicole den Elzen;Hartmut C. Vodermaier;Irene C. Waizenegger

  • Cubism and the cell cycle: the many faces of the APC/C

    Jonathon Pines

  • A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex.

    Stephen H. Devoto;Maria Mudryj;Jonathon Pines;Tony Hunter

Frequent Co-Authors

Tony Hunter
Tony Hunter Salk Institute for Biological Studies
Magdalena Zernicka-Goetz
Magdalena Zernicka-Goetz California Institute of Technology
Tim Hunt
Tim Hunt University of Cambridge
Jyoti S. Choudhary
Jyoti S. Choudhary Institute of Cancer Research
Joseph R. Nevins
Joseph R. Nevins Duke University
Geert J. P. L. Kops
Geert J. P. L. Kops Royal Netherlands Academy of Arts and Sciences
Iain M. Hagan
Iain M. Hagan University of Manchester
Erich A. Nigg
Erich A. Nigg University of Basel
Patrick M. O'Connor
Patrick M. O'Connor National Institutes of Health
Ronald A. Laskey
Ronald A. Laskey University of Cambridge

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