What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in Cell biology, Cyclin A, Cyclin A2, Cyclin B and Cyclin B1.
The Cell biology study combines topics in areas such as S-phase-promoting factor, Anaphase-promoting complex, Cell cycle, G2 phase and Cdc20 Proteins.
His Anaphase-promoting complex research incorporates elements of Spindle checkpoint and CDC20.
The various areas that Jonathon Pines examines in his Cyclin A study include Cyclin-dependent kinase complex, Molecular biology, Retinoblastoma-Like Protein p107 and E2F Transcription Factors.
His study looks at the intersection of Cyclin A2 and topics like Cyclin E with Cyclin-dependent kinase.
His Cyclin B study typically links adjacent topics like Cyclin D.
His most cited work include:
- Cyclins and cancer II: Cyclin D and CDK inhibitors come of age (1886 citations)
- Isolation of a human cyclin cDNA: Evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2 (749 citations)
- Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport. (727 citations)
What are the main themes of his work throughout his whole career to date?
Jonathon Pines spends much of his time researching Cell biology, Mitosis, Cell cycle, Cyclin A and Cyclin B1.
His Cell biology study integrates concerns from other disciplines, such as Spindle checkpoint, Anaphase-promoting complex, Cyclin, Cyclin B and CDC20.
He focuses mostly in the field of Cyclin, narrowing it down to topics relating to Cyclin-dependent kinase and, in certain cases, Polo-like kinase.
His Mitosis research is multidisciplinary, relying on both Cyclin-dependent kinase 1, Prophase, Interphase and PLK1.
His work carried out in the field of Cyclin A brings together such families of science as Cyclin A2, Molecular biology, G1/S transition, Cyclin-dependent kinase complex and G2 phase.
His Cyclin A2 research is multidisciplinary, incorporating perspectives in Cyclin E and Cyclin D.
He most often published in these fields:
- Cell biology (85.43%)
- Mitosis (40.40%)
- Cell cycle (29.80%)
What were the highlights of his more recent work (between 2012-2020)?
- Cell biology (85.43%)
- Mitosis (40.40%)
- Spindle checkpoint (20.53%)
In recent papers he was focusing on the following fields of study:
Jonathon Pines spends much of his time researching Cell biology, Mitosis, Spindle checkpoint, Anaphase-promoting complex and Cyclin B1.
His Cell biology research focuses on CDC20 and how it relates to APC/C activator protein CDH1.
His Mitosis research incorporates themes from Biochemistry, Cyclin B, Wee1, Cell cycle and Cdc25.
In his study, Cdc20 Proteins is inextricably linked to Mitotic checkpoint complex, which falls within the broad field of Spindle checkpoint.
His Cyclin B1 study frequently intersects with other fields, such as Cyclin A.
His Spindle apparatus research includes themes of Cyclin A2 and PLK1.
Between 2012 and 2020, his most popular works were:
- The spindle assembly checkpoint works like a rheostat rather than a toggle switch (158 citations)
- The mitotic checkpoint complex binds a second CDC20 to inhibit active APC/C (125 citations)
- A PP1-PP2A phosphatase relay controls mitotic progression. (119 citations)
In his most recent research, the most cited papers focused on:
Jonathon Pines mostly deals with Spindle checkpoint, Mitotic checkpoint complex, Cell biology, Kinetochore and Wilms' tumor.
His Spindle checkpoint research includes elements of Anaphase-promoting complex, Anaphase, CDC20 and APC/C activator protein CDH1.
His Anaphase study often links to related topics such as Spindle apparatus.
The concepts of his APC/C activator protein CDH1 study are interwoven with issues in BUB1 and Cdc20 Proteins.
His Wilms' tumor study incorporates themes from Carcinogenesis, Cancer research, Aneuploidy and Microcephaly.
His Mitotic exit research integrates issues from Cdc14, Mitosis, Protein phosphatase 1 and Cyclin B.
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