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J. Pablo Radicella

J. Pablo Radicella

D-Index & Metrics

Genetics

D-Index
47
Citations
9920
World Ranking
4114
National Ranking
213

Overview

J. Pablo Radicella is affiliated with Grenoble Alpes University in France and specializes in biochemistry, genetics, and molecular biology with a focus on molecular biology. Their research portfolio comprises 44 publications primarily related to DNA repair mechanisms, DNA and nucleic acid chemistry, and CRISPR and genetic engineering.

The scientist has contributed to several studies addressing diverse biological and genetic topics. Main topics of research include:

  • DNA Repair Mechanisms
  • DNA and Nucleic Acid Chemistry
  • CRISPR and Genetic Engineering
  • Helicobacter pylori-related gastroenterology studies
  • Clostridium difficile and Clostridium perfringens research
  • Bacterial Genetics and Biotechnology
  • Genomics and Chromatin Dynamics

Radicella has published in a variety of scientific venues, with the most frequent being:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Nucleic Acids Research
  • DNA repair
  • International Journal of Molecular Sciences

Recent papers by Radicella feature multiple collaborative efforts in molecular biology and genetics, including:

  • "A peptide of a type I toxin−antitoxin system induces Helicobacter pylori morphological transformation from spiral shape to coccoids," 2020, published in Proceedings of the National Academy of Sciences
  • "Lost in the Crowd: How Does Human 8-Oxoguanine DNA Glycosylase 1 (OGG1) Find 8-Oxoguanine in the Genome?", 2020, published in International Journal of Molecular Sciences
  • "Chromatin recruitment of OGG1 requires cohesin and mediator and is essential for efficient 8-oxoG removal," 2020, published in Nucleic Acids Research
  • "Tumor resistance to radiotherapy is triggered by an ATM/TAK1-dependent-increased expression of the cellular prion protein," 2021, published in Oncogene
  • "Foetal exposure to the bisphenols BADGE and BPAF impairs meiosis through DNA oxidation in mouse ovaries," 2022, published in Environmental Pollution

Frequent co-authors collaborating with Radicella include Anna Campalans, Capucine Siberchicot, Guillaume Pinna, Jordane Dépagne, and Didier Busso. These partnerships reflect a focused research network engaging on topics relevant to molecular biology, DNA repair, and genetics.

Best Publications

  • Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae

    Radicella Jp;Dherin C;Desmaze C;Fox Ms

  • The human OGG1 gene: structure, functions, and its implication in the process of carcinogenesis.

    Serge Boiteux;J.Pablo Radicella

  • XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein–protein interactions

    Antonio E. Vidal;Serge Boiteux;Ian D. Hickson;J. Pablo Radicella

  • Two regulatory genes of the maize anthocyanin pathway are homologous: isolation of B utilizing R genomic sequences.

    V L Chandler;J P Radicella;T P Robbins;J Chen

  • Mechanism of stimulation of the DNA glycosylase activity of hOGG1 by the major human AP endonuclease: bypass of the AP lyase activity step

    Antonio E. Vidal;Ian D. Hickson;Serge Boiteux;J. Pablo Radicella

  • Transactivation of anthocyanin biosynthetic genes following transfer of B regulatory genes into maize tissues.

    S. A. Goff;T. M. Klein;B. A. Roth;M. E. Fromm

  • Role of XRCC1 in the Coordination and Stimulation of Oxidative DNA Damage Repair Initiated by the DNA Glycosylase hOGG1

    Stéphanie Marsin;Antonio E. Vidal;Marguerite Sossou;Josiane Ménissier-de Murcia

  • Base excision repair of 8-hydroxyguanine protects DNA from endogenous oxidative stress.

    S Boiteux;J P Radicella

  • Mutations in OGG1, a gene involved in the repair of oxidative DNA damage, are found in human lung and kidney tumours.

    S Chevillard;J P Radicella;C Levalois;J Lebeau

  • Excision of oxidatively damaged DNA bases by the human α-hOgg1 protein and the polymorphic α-hOgg1(Ser326Cys) protein which is frequently found in human populations

    Claudine Dherin;J. Pablo Radicella;Miral Dizdaroglu;Serge Boiteux

  • APE1/Ref-1 Interacts with NPM1 within Nucleoli and Plays a Role in the rRNA Quality Control Process

    Carlo Vascotto;Damiano Fantini;Milena Romanello;Laura Cesaratto

  • REDOX REGULATION OF HUMAN OGG1 ACTIVITY IN RESPONSE TO CELLULAR OXIDATIVE STRESS

    Anne Bravard;Anne Bravard;Monique Vacher;Monique Vacher;Barbara Gouget;Alexandre Coutant

  • Oxidation Status of Human OGG1-S326C Polymorphic Variant Determines Cellular DNA Repair Capacity

    Anne Bravard;Monique Vacher;Eva Moritz;Laurence Vaslin

  • XRCC1 interactions with multiple DNA glycosylases: a model for its recruitment to base excision repair.

    Anna Campalans;Stéphanie Marsin;Yusaku Nakabeppu;Timothy R. O’Connor

  • Effect of single mutations in the OGG1 gene found in human tumors on the substrate specificity of the Ogg1 protein.

    Marc Audebert;J. Pablo Radicella;Miral Dizdaroglu

  • Oxidative stress triggers the preferential assembly of base excision repair complexes on open chromatin regions

    Rachel Amouroux;Anna Campalans;Bernd Epe;J. Pablo Radicella

  • Poly(ADP‐ribosyl)ation accelerates DNA repair in a pathway dependent on Cockayne syndrome B protein

    Claudia Flohr;Alexander Bürkle;J. Pablo Radicella;Bernd Epe

  • Characterization of the hOGG1 promoter and its expression during the cell cycle.

    Andreia Dhénaut;Serge Boiteux;J.Pablo Radicella

  • Pathogen DNA as target for host-generated oxidative stress: role for repair of bacterial DNA damage in Helicobacter pylori colonization

    Eyleen J. O'Rourke;Catherine Chevalier;A. Viviana Pinto;Jean Michel Thiberge

  • Alterations of the DNA Repair Gene OGG1 in Human Clear Cell Carcinomas of the Kidney

    Marc Audebert;Sylvie Chevillard;Céline Levalois;Gabor Gyapay

Frequent Co-Authors

Serge Boiteux
Serge Boiteux Centre national de la recherche scientifique, CNRS
Bernd Epe
Bernd Epe Johannes Gutenberg University of Mainz
Jean-Philippe Vert
Jean-Philippe Vert Google (United States)
Gianluca Tell
Gianluca Tell University of Udine
Miral Dizdaroglu
Miral Dizdaroglu National Institute of Standards and Technology
Agnès Labigne
Agnès Labigne Institut Pasteur
Andrea Scaloni
Andrea Scaloni National Academies of Sciences, Engineering, and Medicine
Ivo G. Boneca
Ivo G. Boneca Institut Pasteur
Wim Vermeulen
Wim Vermeulen Erasmus University Rotterdam
Ian D. Hickson
Ian D. Hickson University of Copenhagen

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