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Chemistry
France
2025

D-Index & Metrics

Chemistry

D-Index
78
Citations
21240
World Ranking
3816
National Ranking
110

Research.com Recognitions

  • 2025 - Research.com Chemistry in France Leader Award
  • 2022 - Research.com Chemistry in France Leader Award

Overview

Jean-Luc Ravanat is affiliated with Grenoble Alpes University in France. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, with a strong emphasis on Molecular Biology as a subfield.

The scientist's work spans several specialized topics including:

  • Metalloenzymes and iron-sulfur proteins
  • DNA Repair Mechanisms
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • DNA and Nucleic Acid Chemistry
  • Nanoplatforms for cancer theranostics
  • Radiation Therapy and Dosimetry

Frequent coauthors collaborating with Jean-Luc Ravanat include:

  • Sylvain Caillat
  • Béatrice Golinelli-Pimpaneau
  • Jingjing Zhou
  • Marc Fontecave
  • Hélène Elleaume

Their publication record includes articles in prominent venues such as:

  • Nucleic Acids Research
  • Scientific Reports
  • Particle and Fibre Toxicology
  • Journal of Inorganic Biochemistry
  • bioRxiv (Cold Spring Harbor Laboratory)

Recent notable papers authored or coauthored by Jean-Luc Ravanat include:

  • Radiation Dose-Enhancement Is a Potent Radiotherapeutic Effect of Rare-Earth Composite Nanoscintillators in Preclinical Models of Glioblastoma, 2020, Advanced Science
  • Dose-dependent genomic DNA hypermethylation and mitochondrial DNA damage in Japanese tree frogs sampled in the Fukushima Daiichi area, 2020, Journal of Environmental Radioactivity
  • Iron-sulfur biology invades tRNA modification: the case of U34 sulfuration, 2021, Nucleic Acids Research
  • Chromatin recruitment of OGG1 requires cohesin and mediator and is essential for efficient 8-oxoG removal, 2020, Nucleic Acids Research
  • Reactivity of Singlet Oxygen with DNA, an Update†, 2021, Photochemistry and Photobiology

Jean-Luc Ravanat has contributed to book publications, including one with the Centre National de la Recherche Scientifique titled Twelve Years of LabEx PRIMES (2012-2024), expected in 2025.

Best Publications

  • Direct and indirect effects of UV radiation on DNA and its components.

    Jean-Luc Ravanat;Thierry Douki;Jean Cadet

  • Oxidative damage to DNA: formation, measurement and biochemical features.

    Jean Cadet;Thierry Douki;Didier Gasparutto;Jean-Luc Ravanat

  • Hydroxyl radicals and DNA base damage

    Jean Cadet;Thierry Delatour;Thierry Douki;Didier Gasparutto

  • Oxidative damage to DNA: formation, measurement, and biological significance.

    J. Cadet;M. Berger;T. Douki;J. L. Ravanat

  • Oxidatively generated base damage to cellular DNA.

    Jean Cadet;Thierry Douki;Jean-Luc Ravanat

  • Oxidatively generated damage to the guanine moiety of DNA: mechanistic aspects and formation in cells.

    Jean Cadet;Thierry Douki;Jean-Luc Ravanat

  • Chemical quenching of singlet oxygen by carotenoids in plants

    Fanny Ramel;Simona Birtic;Stéphan Cuiné;Christian Triantaphylidès

  • 2,2-Diamino-4-[(3,5-di-O-acetyl-2-deoxy-.beta.-D-erythro- pentofuranosyl)amino]-5-(2H)-oxazolone: a Novel and Predominant Radical Oxidation Product of 3',5'-Di-O-acetyl-2'-deoxyguanosine

    Jean Cadet;Maurice Berger;Garry W. Buchko;Prakash C. Joshi

  • Singlet oxygen induces oxidation of cellular DNA.

    Jean-Luc Ravanat;Paolo Di Mascio;Glaucia R. Martinez;Marisa H.G. Medeiros

  • Oxidatively generated damage to cellular DNA by UVB and UVA radiation.

    Jean Cadet;Thierry Douki;Jean-Luc Ravanat

  • Cellular background level of 8-oxo-7,8-dihydro-2′-deoxyguanosine: an isotope based method to evaluate artefactual oxidation of DNA during its extraction and subsequent work-up

    Jean-Luc Ravanat;Thierry Douki;Pierre Duez;Eric Gremaud

  • Photoinduced Damage to Cellular DNA: Direct and Photosensitized Reactions†

    Jean Cadet;Stéphane Mouret;Jean-Luc Ravanat;Thierry Douki

  • High-performance liquid chromatography--tandem mass spectrometry measurement of radiation-induced base damage to isolated and cellular DNA.

    Sandrine Frelon;Thierry Douki;Jean-Luc Ravanat;Jean-Pierre Pouget

  • Effects of UV and visible radiation on DNA-final base damage.

    Cadet J;Berger M;Douki T;Morin B

  • Determination of 8-Oxoguanine in DNA by Gas Chromatography-Mass Spectrometry and HPLC-Electrochemical Detection: Overestimation of the Background Level of the Oxidized Base by the Gas Chromatography-Mass Spectrometry Assay

    Jean Luc Ravanat;Robert J. Turesky;Eric Gremaud;Laura J. Trudel

  • Formation of modified DNA bases in cells exposed either to gamma radiation or to high-LET particles.

    Pouget Jp;Frelon S;Ravanat Jl;Testard I

  • Oxidative Stress, DNA Damage, and Inflammation Induced by Ambient Air and Wood Smoke Particulate Matter in Human A549 and THP-1 Cell Lines

    Pernille Høgh Danielsen;Peter Møller;Keld Alstrup Jensen;Anoop Kumar Sharma

  • Riboflavin and UV-light based pathogen reduction: extent and consequence of DNA damage at the molecular level.

    Vijay Kumar;Owen Lockerbie;Shawn D. Keil;Patrick H. Ruane

  • Preventive effect of zinc against cadmium-induced oxidative stress in the rat testis.

    Salem Amara;Hafedh Abdelmelek;Catherine Garrel;Pascale Guiraud

  • Hydrogen peroxide causes greater oxidation in cellular RNA than in DNA

    Tim Hofer;Carine Badouard;Edyta Bajak;Jean-Luc Ravanat

  • REACTION OF SINGLET OXYGEN WITH 2'-DEOXYGUANOSINE AND DNA. ISOLATION AND CHARACTERIZATION OF THE MAIN OXIDATION PRODUCTS

    Jean-Luc Ravanat;Jean Cadet

Frequent Co-Authors

Jean Cadet
Jean Cadet Université de Sherbrooke
Thierry Douki
Thierry Douki Grenoble Alpes University
Paolo Di Mascio
Paolo Di Mascio Universidade de São Paulo
Marisa H. G. Medeiros
Marisa H. G. Medeiros Universidade de São Paulo
Jean-Marc Latour
Jean-Marc Latour Grenoble Alpes University
Marc Fontecave
Marc Fontecave Collège de France
Michel Havaux
Michel Havaux Aix-Marseille University
Marie Carrière
Marie Carrière Grenoble Alpes University
Steffen Loft
Steffen Loft University of Copenhagen
Alexandros G. Georgakilas
Alexandros G. Georgakilas National Technical University of Athens

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