2012 - Fellow of the American Association for the Advancement of Science (AAAS)
2010 - Fellow of the American Chemical Society
1981 - Fellow of American Physical Society (APS)
Nicholas E. Geacintov mainly investigates DNA, Stereochemistry, Adduct, Molecular biology and DNA polymerase. His work on Guanine expands to the thematically related DNA. His Guanine study integrates concerns from other disciplines, such as Photochemistry, Radical and Thymine.
In his research on the topic of Stereochemistry, Duplex is strongly related with A-DNA. He has researched Adduct in several fields, including Diol, Nucleotide and Benzopyrene, Pyrene. His DNA polymerase research is multidisciplinary, incorporating elements of DNA polymerase delta, Polymerase, DNA synthesis and Mutagenesis.
His scientific interests lie mostly in DNA, Stereochemistry, Adduct, Guanine and Photochemistry. DNA and Molecular biology are commonly linked in his work. He has included themes like Covalent bond, Base pair, Diol, Oligonucleotide and A-DNA in his Stereochemistry study.
Nicholas E. Geacintov interconnects Enantiomer and Pyrene, Benzopyrene in the investigation of issues within Adduct. His work carried out in the field of Guanine brings together such families of science as Cytosine and Thymine. His work deals with themes such as Ultrafast laser spectroscopy, Fluorescence, Excited state, Radical and Aqueous solution, which intersect with Photochemistry.
DNA, Nucleotide excision repair, DNA repair, Guanine and DNA damage are his primary areas of study. His DNA research includes themes of Molecular biology, Adduct and Stereochemistry. His work in Stereochemistry covers topics such as Duplex which are related to areas like Stacking.
His study in DNA repair is interdisciplinary in nature, drawing from both Base pair, Genome instability and DNA replication. His Guanine study combines topics from a wide range of disciplines, such as Medicinal chemistry, Covalent bond, Photochemistry, Thymine and Radical. His studies examine the connections between DNA damage and genetics, as well as such issues in Biophysics, with regards to Nucleosome and Histone.
Nicholas E. Geacintov mainly focuses on DNA, DNA repair, DNA damage, Guanine and Nucleotide excision repair. DNA and Stereochemistry are frequently intertwined in his study. The various areas that Nicholas E. Geacintov examines in his Stereochemistry study include Duplex, Adduct, DNA adduct and Stacking.
His DNA repair study incorporates themes from Molecular biology, Transcription factor and BTG2. His Homology directed repair study in the realm of DNA damage interacts with subjects such as GADD45A. His Guanine research incorporates elements of Peroxynitrite, Photochemistry, Radical and Pyrene.
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NMR SOLUTION STRUCTURES OF STEREOISOMERIC COVALENT POLYCYCLIC AROMATIC CARCINOGEN-DNA ADDUCTS : PRINCIPLES, PATTERNS, AND DIVERSITY
Nicholas E. Geacintov;Monique Cosman;Brian E. Hingerty;Shantu Amin.
Chemical Research in Toxicology (1997)
Error-free and error-prone lesion bypass by human DNA polymerase κ in vitro
Yanbin Zhang;Fenghua Yuan;Xiaohua Wu;Mu Wang;Mu Wang.
Nucleic Acids Research (2000)
Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA.
Monique Cosman;Carlos de los Santos;Radovan Fiala;Brian E. Hingerty.
Proceedings of the National Academy of Sciences of the United States of America (1992)
Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals
Sigal Shachar;Omer Ziv;Sharon Avkin;Sheera Adar.
The EMBO Journal (2009)
Error-prone lesion bypass by human DNA polymerase η
Yanbin Zhang;Fenghua Yuan;Xiaohua Wu;Olga Rechkoblit.
Nucleic Acids Research (2000)
Oxidative DNA damage associated with combination of guanine and superoxide radicals and repair mechanisms via radical trapping
Richard Misiaszek;Conor Crean;Avrum Joffe;Nicholas E. Geacintov.
Journal of Biological Chemistry (2004)
Intercalation and binding of carcinogenic hydrocarbon metabolites to nucleic acids
Ronald G. Harvey;Nicholas E. Geacintov.
Accounts of Chemical Research (1988)
trans-Lesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases.
Olga Rechkoblit;Yanbin Zhang;Dongyu Guo;Zhigang Wang.
Journal of Biological Chemistry (2002)
Translesion Synthesis by Human DNA Polymerase κ on a DNA Template Containing a Single Stereoisomer of dG-(+)- or dG-(−)-anti-N2-BPDE (7,8-Dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene)†
Naomi Suzuki;Eiji Ohashi;Alexander Kolbanovskiy;Nicholas E. Geacintov.
Base pair conformation-dependent excision of benzo[a]pyrene diol epoxide-guanine adducts by human nucleotide excision repair enzymes.
Martin T. Hess;Daniela Gunz;Natalia Luneva;Nicholas E. Geacintov.
Molecular and Cellular Biology (1997)
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