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Biology and Biochemistry

D-Index
56
Citations
11958
World Ranking
14378
National Ranking
6056

Overview

Pawel Jaruga is affiliated with the National Institute of Standards and Technology in the United States. Their research primarily focuses on molecular biology and biochemistry, with a particular emphasis on DNA repair mechanisms and genetic studies. Their scholarly output spans various areas including DNA damage and repair, genotoxicity assessment, and the chemical interactions involving nucleic acids.

Their recent publications encompass a range of topics related to DNA damage and repair processes. Key papers include:

  • Heavy ion space radiation triggers ongoing DNA base damage by downregulating DNA repair pathways, 2020, Life Sciences in Space Research
  • Ne-22 Ion-Beam Radiation Damage to DNA: From Initial Free Radical Formation to Resulting DNA-Base Damage, 2021, ACS Omega
  • Possible Genetic Risks from Heat-Damaged DNA in Food, 2023, ACS Central Science
  • Synthesis and Characterization of 15N5-Labeled Aflatoxin B1-Formamidopyrimidines and Aflatoxin B1-N7-Guanine from a Partial Double-Stranded Oligodeoxynucleotide as Internal Standards for Mass Spectrometric Measurements, 2023, ACS Omega
  • Functional analyses of single nucleotide polymorphic variants of the DNA glycosylase NEIL1 in sub-Saharan African populations, 2023, DNA repair

Collaborations have been a significant part of their research activities. Frequent co-authors include:

  • Miral Dizdaroğlu
  • Melis Kant
  • R. Stephen Lloyd
  • Erdem Coşkun
  • Irina G. Minko

Their publication record is predominantly associated with these scientific venues:

  • DNA repair
  • ACS Omega
  • ACS Central Science
  • Life Sciences in Space Research
  • Environmental Toxicology and Pharmacology

Pawel Jaruga's work addresses several main fields of study, notably:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, they delve deeper into subfields such as:

  • Molecular Biology
  • Plant Science
  • Cancer Research
  • Public Health, Environmental and Occupational Health
  • Epidemiology

Their research covers diverse topics, including:

  • DNA Repair Mechanisms
  • CRISPR and Genetic Engineering
  • Carcinogens and Genotoxicity Assessment
  • Plant Pathogens and Resistance
  • DNA and Nucleic Acid Chemistry
  • RNA regulation and disease
  • Mycotoxins in Agriculture and Food

Best Publications

  • Free radical-induced damage to DNA: mechanisms and measurement.

    Miral Dizdaroglu;Pawel Jaruga;Mustafa Birincioglu;Henry Rodriguez

  • Mechanisms of free radical-induced damage to DNA

    Miral Dizdaroglu;Pawel Jaruga

  • Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA.

    Tapas K. Hazra;Tadahide Izumi;Istvan Boldogh;Barry Imhoff

  • Copper Oxide Nanoparticle Mediated DNA Damage in Terrestrial Plant Models

    Donald H Atha;Huanhua Wang;Elijah J Petersen;Danielle Cleveland

  • DNA damage and DNA sequence retrieval from ancient tissues.

    Matthias Höss;Pawel Jaruga;Tomasz H. Zastawny;Miral Dizdaroglu

  • Oxidative DNA damage: assessment of the role in carcinogenesis, atherosclerosis, and acquired immunodeficiency syndrome.

    Ryszard Olinski;Daniel Gackowski;Marek Foksinski;Rafal Rozalski

  • Repair of Products of Oxidative DNA Base Damage in Human Cells

    Pawel Jaruga;Miral Dizdaroglu

  • Oxidative DNA base damage and antioxidant enzyme activities in human lung cancer.

    Pawel Jaruga;Tomasz H. Zastawny;Jan Skokowski;Miral Dizdaroglu

  • New functions of XPC in the protection of human skin cells from oxidative damage

    Mariarosaria D'Errico;Eleonora Parlanti;Massimo Teson;Bruno M Bernardes De Jesus

  • Regulation of reactive oxygen species, DNA damage, and c-Myc function by peroxiredoxin 1.

    Rachel A Egler;Elaine Fernandes;Kristi Rothermund;Susan Sereika

  • Repair of Formamidopyrimidines in DNA Involves Different Glycosylases ROLE OF THE OGG1, NTH1, AND NEIL1 ENZYMES

    Jingping Hu;Nadja C. de Souza-Pinto;Kazuhiro Haraguchi;Barbara A. Hogue

  • The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo

    Minmin Liu;Viswanath Bandaru;Jeffrey P. Bond;Pawel Jaruga;Pawel Jaruga

  • Kinetics of Excision of Purine Lesions from DNA by Escherichia Coli Fpg Protein

    Asuman Karakaya;Pawel Jaruga;Vilhelm A. Bohr;Arthur P. Grollman

  • Polyamines stimulate the formation of mutagenic 1,N2-propanodeoxyguanosine adducts from acetaldehyde

    Jacob A. Theruvathu;Pawel Jaruga;Raghu G. Nath;Miral Dizdaroglu

  • The Cockayne Syndrome group B gene product is involved in general genome base excision repair of 8-hydroxyguanine in DNA.

    Jingsheng Tuo;Meltem Müftüoglu;Catheryne Chen;Pawel Jaruga

  • The role of CSA in the response to oxidative DNA damage in human cells.

    M D'Errico;E Parlanti;M Teson;P Degan

  • Primary fibroblasts of Cockayne syndrome patients are defective in cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting from oxidative stress

    Jingsheng Tuo;Pawel Jaruga;Henry Rodriguez;Vilhelm A. Bohr

  • Supplementation with antioxidant vitamins prevents oxidative modification of DNA in lymphocytes of HIV-infected patients.

    Pawel Jaruga;Barbara Jaruga;Daniel Gackowski;Anita Olczak

  • Measurement of 8-hydroxy-2′-deoxyguanosine in DNA by high-performance liquid chromatography-mass spectrometry: comparison with measurement by gas chromatography-mass spectrometry

    Miral Dizdaroglu;Pawel Jaruga;Henry Rodriguez

  • Formamidopyrimidines in DNA: mechanisms of formation, repair, and biological effects.

    Miral Dizdaroglu;Güldal Kirkali;Pawel Jaruga

Frequent Co-Authors

Miral Dizdaroglu
Miral Dizdaroglu National Institute of Standards and Technology
Henry Rodriguez
Henry Rodriguez National Institutes of Health
Ryszard Olinski
Ryszard Olinski Nicolaus Copernicus University
R. Stephen Lloyd
R. Stephen Lloyd Oregon Health & Science University
Vilhelm A. Bohr
Vilhelm A. Bohr University of Copenhagen
David G. Maloney
David G. Maloney Fred Hutchinson Cancer Research Center
Ajit Jadhav
Ajit Jadhav Pfizer (Germany)
Anton Simeonov
Anton Simeonov National Institutes of Health
Thomas Helleday
Thomas Helleday Karolinska Institute
Susan S. Wallace
Susan S. Wallace University of Vermont

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