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Chemistry

D-Index
56
Citations
7862
World Ranking
11943
National Ranking
101

Overview

Dan Staerk is affiliated with the University of Copenhagen in Denmark and has made contributions across multiple scientific disciplines. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Medicine, and Agricultural and Biological Sciences.

The subfields Staerk has focused on include Molecular Biology, Pharmacology, Plant Science, Organic Chemistry, and Complementary and Alternative Medicine.

The main research topics covered in their publications encompass:

  • Natural product bioactivities and synthesis
  • Plant biochemistry and biosynthesis
  • Microbial natural products and biosynthesis
  • Phytochemistry and biological activities
  • Genomics, phytochemicals, and oxidative stress
  • Natural compounds in disease treatment
  • Bioactive compounds and antitumor agents

Staerk's frequent coauthors include Birger Lindberg Møller, Louise Kjærulff, Susan J. Semple, Yong Zhao, and Bevan Buirchell.

Among the venues where Staerk has published prominently are Nature Communications, Journal of Natural Products, Biochemical Systematics and Ecology, Phytochemistry, and Molecules.

Some of their recent papers are listed below:

  • "A gene cluster in Ginkgo biloba encodes unique multifunctional cytochrome P450s that initiate ginkgolide biosynthesis" (2022, Nature Communications)
  • "Antidiabetic xanthones with α-glucosidase inhibitory activities from an endophytic Penicillium canescens" (2020, Fitoterapia)
  • "A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination" (2022, Nature Communications)
  • "Expanding the terpene biosynthetic code with non-canonical 16 carbon atom building blocks" (2022, Nature Communications)
  • "Tripterygium wilfordii cytochrome P450s catalyze the methyl shift and epoxidations in the biosynthesis of triptonide" (2022, Nature Communications)

Best Publications

  • Capillary electrophoretic chiral separations with cyclodextrin additives: I. acids: Chiral selectivity as a function of pH and the concentration of β-cyclodextrin for fenoprofen and ibuprofen

    Yasir Y. Rawjee;Daniel U. Staerk;Gyula Vigh

  • Ancistrotanzanine C and related 5,1'- and 7,3'-coupled naphthylisoquinoline alkaloids from Ancistrocladus tanzaniensis.

    Gerhard Bringmann;Michael Dreyer;Johan H. Faber;Petur Weihe Dalsgaard

  • In Vitro Cytotoxic Activity of Phenanthroindolizidine Alkaloids from Cynanchum vincetoxicum and Tylophora tanakae against Drug-Sensitive and Multidrug-Resistant Cancer Cells

    Dan Stærk;Anne K. Lykkeberg;Jette Christensen;Bogdan A. Budnik

  • Leishmanicidal, antiplasmodial, and cytotoxic activity of novel diterpenoid 1,2-quinones from Perovskia abrotanoides: new source of tanshinones.

    Majid Sairafianpour;Jette Christensen;Dan Staerk;Bogdan A. Budnik

  • Expanding the Landscape of Diterpene Structural Diversity through Stereochemically Controlled Combinatorial Biosynthesis.

    Johan Andersen-Ranberg;Kenneth Thermann Kongstad;Morten Thrane Nielsen;Niels Bjerg Jensen

  • Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: structure-activity relationships for betulinic acid analogues.

    Hanne L Ziegler;Henrik Franzyk;Majid Sairafianpour;Mehrnoush Tabatabai

  • Butenolides from plant-derived smoke: natural plant-growth regulators with antagonistic actions on seed germination.

    Marnie E Light;Ben V Burger;Dan Staerk;Ladislav Kohout

  • Screening for potential α-glucosidase and α-amylase inhibitory constituents from selected Vietnamese plants used to treat type 2 diabetes.

    Binh T.D. Trinh;Dan Staerk;Anna K. Jäger

  • Cytotoxic activity of some phenanthroindolizidine N-oxide alkaloids from Cynanchum vincetoxicum.

    Dan Stærk;Jette Christensen;Else Lemmich;Jens Øllgaard Duus

  • Total biosynthesis of the cyclic AMP booster forskolin from Coleus forskohlii

    Irini Pateraki;Johan Andersen-Ranberg;Niels Bjerg Jensen;Sileshi Gizachhew Wubshet

  • In Vitro Plasmodium falciparum Drug Sensitivity Assay: Inhibition of Parasite Growth by Incorporation of Stomatocytogenic Amphiphiles into the Erythrocyte Membrane

    Hanne L. Ziegler;Dan Stærk;Jette Christensen;Lars Hviid

  • Development of a bioassay-coupled HPLC-SPE-ttNMR platform for identification of α-glucosidase inhibitors in apple peel (Malus ×domestica Borkh.).

    Jeppe S. Schmidt;Michael B. Lauridsen;Lars O. Dragsted;John Nielsen

  • Hyphenation of solid-phase extraction with liquid chromatography and nuclear magnetic resonance: application of HPLC-DAD-SPE-NMR to identification of constituents of Kanahia laniflora.

    Cailean Clarkson;Dan Staerk;Steen Honoré Hansen;Jerzy W. Jaroszewski

  • Leishmanicidal, antiplasmodial and cytotoxic activity of indole alkaloids from Corynanthe pachyceras.

    Dan Stærk;Else Lemmich;Jette Christensen;Arsalan Kharazmi

  • Identification of natural products using HPLC-SPE combined with CapNMR

    Maja Lambert;Jean-Luc Wolfender;Dan Stærk;S. Brøgger Christensen

  • Two Novel Classes of Enzymes Are Required for the Biosynthesis of Aurofusarin in Fusarium graminearum

    Rasmus John Normand Frandsen;Rasmus John Normand Frandsen;Claes Schütt;Birgitte W. Lund;Dan Staerk

  • Biosynthesis of bioactive diterpenoids in the medicinal plant Vitex agnus‐castus

    Allison M. Heskes;Tamil Chelvan Meenakshi Sundram;Tamil Chelvan Meenakshi Sundram;Berin A. Boughton;Niels Bjerg Jensen

  • Magnetic Ligand Fishing as a Targeting Tool for HPLC-HRMS-SPE-NMR: α-Glucosidase Inhibitory Ligands and Alkylresorcinol Glycosides from Eugenia catharinae.

    Sileshi G. Wubshet;Inês M. C. Brighente;Ruin Moaddel;Dan Staerk

  • Edible seaweed as future functional food: Identification of α-glucosidase inhibitors by combined use of high-resolution α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR.

    Bingrui Liu;Kenneth T. Kongstad;Stefanie Wiese;Anna K. Jäger

  • Rapid Extract Dereplication Using HPLC-SPE-NMR: Analysis of Isoflavonoids from Smirnowia iranica

    Maja Lambert;Dan Staerk;Steen Honoré Hansen;Majid Sairafianpour

  • 1H NMR-based metabolomics combined with HPLC-PDA-MS-SPE-NMR for investigation of standardized Ginkgo biloba preparations

    Sara Agnolet;Jerzy W. Jaroszewski;Robert Verpoorte;Dan Staerk

  • Inhibition of α-glucosidase activity by selected edible seaweeds and fucoxanthin.

    Nazikussabah Binti Zaharudin;Nazikussabah Binti Zaharudin;Dan Stærk;Lars Ove Dragsted

Frequent Co-Authors

Birger Lindberg Møller
Birger Lindberg Møller University of Copenhagen
Ulf Thrane
Ulf Thrane Technical University of Denmark
Matthias Witt
Matthias Witt Laboratorien Dr. Döring GmbH
Carl Erik Olsen
Carl Erik Olsen University of Copenhagen
Steen Honoré Hansen
Steen Honoré Hansen University of Copenhagen
Pieter C. Dorrestein
Pieter C. Dorrestein University of California, San Diego
Peter Smith
Peter Smith University of Aberdeen
Marnix H. Medema
Marnix H. Medema Wageningen University & Research
J. Van Staden
J. Van Staden University of KwaZulu-Natal
Justin J. J. van der Hooft
Justin J. J. van der Hooft Wageningen University & Research

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