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Gianluca Tell

Gianluca Tell

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
11556
World Ranking
10969
National Ranking
312

Overview

Gianluca Tell is affiliated with the University of Udine in Italy and has made significant contributions to the field of biochemistry, genetics, and molecular biology. Their research primarily focuses on molecular biology with notable work in cancer research, immunology, oncology, and pathology and forensic medicine.

The scientist's recent publications highlight a diverse range of topics related to RNA biology, cancer progression, and molecular pathways. Key papers include:

  • "Integrated multi-omics analyses on patient-derived CRC organoids highlight altered molecular pathways in colorectal cancer progression involving PTEN" (2021, Journal of Experimental & Clinical Cancer Research)
  • "Coping with RNA damage with a focus on APE1, a BER enzyme at the crossroad between DNA damage repair and RNA processing/decay" (2021, DNA Repair)
  • "Design and advanced characterization of quercetin-loaded nano-liposomes prepared by high-pressure homogenization" (2023, Food Chemistry)
  • "Revisiting Two Decades of Research Focused on Targeting APE1 for Cancer Therapy: The Pros and Cons" (2023, Cells)
  • "Brain Exosomes: Friend or Foe in Alzheimer's Disease?" (2021, Molecular Neurobiology)

Collaborations have been an important aspect of Gianluca Tell's research. Frequent co-authors include Giulia Antoniali, Matilde Clarissa Malfatti, Emiliano Dalla, Marta Codrich, and Giovanna Mangiapane, indicating sustained teamwork and shared investigation efforts.

The scientist's work has been published in several prominent venues, with frequent appearances in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Cells
  • Journal of Biological Chemistry
  • FEBS Journal

The primary fields of study encompass biochemistry, genetics, and molecular biology, with a specialization in molecular biology. Subfields include cancer research, immunology, oncology, and pathology alongside forensic medicine.

Gianluca Tell's research topics show a focus on RNA-related processes and disease mechanisms, including:

  • RNA modifications and cancer
  • RNA research and splicing
  • MicroRNA in disease regulation
  • DNA repair mechanisms
  • Extracellular vesicles in disease
  • RNA interference and gene delivery
  • RNA regulation and disease

The scientist's output demonstrates an intersection between molecular biology, disease modulation, and innovative methodologies for understanding cancer and neurological diseases.

Best Publications

  • Proteins as biomarkers of oxidative/nitrosative stress in diseases: The contribution of redox proteomics

    Isabella Dalle-Donne;Andrea Scaloni;Daniela Giustarini;Eleonora Cavarra

  • The many functions of APE1/Ref-1: Not only a DNA repair enzyme

    Gianluca Tell;Franco Quadrifoglio;Claudio Tiribelli;Mark R. Kelley

  • Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis

    Fabio Marra;Amalia Gastaldelli;Gianluca Svegliati Baroni;Gianluca Tell

  • The intracellular localization of APE1/Ref-1: more than a passive phenomenon?

    Gianluca Tell;Giuseppe Damante;David Caldwell;Mark R. Kelley

  • APE1/Ref-1 Interacts with NPM1 within Nucleoli and Plays a Role in the rRNA Quality Control Process

    Carlo Vascotto;Damiano Fantini;Milena Romanello;Laura Cesaratto

  • The importance of redox state in liver damage.

    Laura Cesaratto;Carlo Vascotto;Sebastian Calligaris;Sebastian Calligaris;Gianluca Tell;Gianluca Tell;Gianluca Tell

  • The neutrophil gelatinase-associated lipocalin (NGAL), a NF-κB-regulated gene, is a survival factor for thyroid neoplastic cells

    Alessio Iannetti;Francesco Pacifico;Renato Acquaviva;Alfonso Lavorgna

  • A unique combination of transcription factors controls differentiation of thyroid cells.

    Giuseppe Damante;Gianluca Tell;Roberto Di Lauro

  • Nuclear localization of Galectin-3 in transformed thyroid cells: a role in transcriptional regulation.

    Igor Paron;Andrea Scaloni;Alex Pines;Angela Bachi

  • Oxidative stress causes bone loss in estrogen-deficient mice through enhanced bone marrow dendritic cell activation

    Francesco Grassi;Gianluca Tell;Michaela Robbie-Ryan;Yuhao Gao

  • Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP.

    Alex Pines;Lorena Perrone;Nicoletta Bivi;Milena Romanello

  • Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions

    Damiano Fantini;Carlo Vascotto;Daniela Marasco;Chiara D’Ambrosio

  • Understanding different functions of mammalian AP endonuclease (APE1) as a promising tool for cancer treatment.

    Gianluca Tell;Damiano Fantini;Franco Quadrifoglio

  • A proteomic approach to identify early molecular targets of oxidative stress in human epithelial lens cells

    Igor Paron;Angela D'Elia;Chiara D'Ambrosio;Andrea Scaloni

  • An ‘environment to nucleus’ signaling system operates in B lymphocytes: redox status modulates BSAP/Pax-5 activation through Ref-1 nuclear translocation

    Gianluca Tell;Alessandro Zecca;Lucia Pellizzari;Paola Spessotto

  • Redox potential controls the structure and DNA binding activity of the paired domain.

    Gianluca Tell;Andrea Scaloni;Lucia Pellizzari;Silvestro Formisano

  • A molecular code dictates sequence-specific DNA recognition by homeodomains.

    G Damante;L Pellizzari;G Esposito;F Fogolari

  • Subcellular localization of APE1/Ref-1 in human hepatocellular carcinoma: possible prognostic significance.

    Vittorio Di Maso;Claudio Avellini;Lory Saveria Crocè;Natalia Rosso

  • H2O2 induces translocation of APE/Ref-1 to mitochondria in the Raji B-cell line

    Barbara Frossi;Gianluca Tell;Paola Spessotto;Alfonso Colombatti

  • Prognostic role of Ape/Ref-1 subcellular expression in stage I-III breast carcinomas

    Fabio Puglisi;Fabio Barbone;Gianluca Tell;Giuseppe Aprile

Frequent Co-Authors

Giuseppe Damante
Giuseppe Damante University of Udine
Andrea Scaloni
Andrea Scaloni National Academies of Sciences, Engineering, and Medicine
Franco Quadrifoglio
Franco Quadrifoglio University of Udine
Claudio Tiribelli
Claudio Tiribelli AREA Science Park
Mark R. Kelley
Mark R. Kelley Indiana University
Sebastiano Filetti
Sebastiano Filetti Sapienza University of Rome
Gennaro Esposito
Gennaro Esposito New York University Abu Dhabi
Stefano Gustincich
Stefano Gustincich Italian Institute of Technology
David M. Wilson
David M. Wilson AstraZeneca (United Kingdom)
Elisabetta Ferretti
Elisabetta Ferretti Sapienza University of Rome

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