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Biology and Biochemistry

D-Index
60
Citations
13413
World Ranking
11916
National Ranking
432

Overview

Bernard Ducommun is affiliated with the Federal University of Toulouse Midi-Pyrénées in France. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, focusing primarily on cellular mechanisms relevant to cancer and cell biology.

The main fields of study covered by their work include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, their research delves into several important subfields:

  • Cell Biology
  • Oncology
  • Molecular Biology
  • Biomedical Engineering

Bernard Ducommun's published work concentrates on several key topics including:

  • Cancer Cells and Metastasis
  • Microtubule and mitosis dynamics
  • Hippo pathway signaling and YAP/TAZ
  • 3D Printing in Biomedical Research
  • Histone Deacetylase Inhibitors Research
  • Epigenetics and DNA Methylation
  • Protein Degradation and Inhibitors

Their recent papers illustrate a focus on tumor cell behavior and potential cancer treatments, with publications such as:

  • Mitotic arrest affects clustering of tumor cells, 2021, Cell Division
  • Quantitative Analysis of Cell Aggregation Dynamics Identifies HDAC Inhibitors as Potential Regulators of Cancer Cell Clustering, 2021, Cancers
  • Mitotic arrest affects clustering of tumor cells, 2020, Research Square
  • Mitotic arrest affects clustering of tumor cells, 2021, Research Square

Bernard Ducommun collaborates regularly with other researchers in related fields. Frequent co-authors include:

  • Odile Mondésert
  • Renaud Morin
  • Valérie Lobjois
  • Julia Bonnet
  • Lise Rigal

The majority of these collaborations have resulted in publications in the following venues:

  • Research Square
  • Cell Division
  • Cancers

This body of work reflects a research focus on how cell cycle regulation and epigenetic factors impact cancer cell dynamics, alongside exploration of molecular pathways involved in tumor progression and potential therapeutic targets.

Best Publications

  • Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy

    C Delettre;G Lenaers;J-M Griffoin;N Gigarel

  • CDC25 phosphatases in cancer cells: key players? Good targets?

    Rose Boutros;Valérie Lobjois;Bernard Ducommun

  • The when and wheres of CDC25 phosphatases.

    Rose Boutros;Christine Dozier;Bernard Ducommun

  • The human dynamin-related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter-membrane space.

    Aurélien Olichon;Laurent J Emorine;Eric Descoins;Laetitia Pelloquin

  • cdc2 phosphorylation is required for its interaction with cyclin

    B. Ducommun;P. Brambilla;M.-A. Felix;B.R. Franza

  • p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells

    Corinne Cayrol;Martine Knibiehler;Bernard Ducommun

  • Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A

    S. Ait-Si-Ali;S. Ramirez;F.-X. Barre;F. Dkhissi

  • Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2–M transition

    Stéphanie Dutertre;Martine Cazales;Muriel Quaranta;Carine Froment

  • Involvement of the Interaction between p21 and Proliferating Cell Nuclear Antigen for the Maintenance of G2/M Arrest after DNA Damage

    Tomoaki Ando;Takumi Kawabe;Hirotaka Ohara;Bernard Ducommun

  • Escherichia coli cytolethal distending toxin blocks the HeLa cell cycle at the G2/M transition by preventing cdc2 protein kinase dephosphorylation and activation.

    C Comayras;C Tasca;S Y Pérès;B Ducommun

  • Identification of binding domains on the p21Cip1 cyclin-dependent kinase inhibitor.

    Goubin F;Ducommun B

  • Interaction with cyclin-dependent kinases and PCNA modulates proteasome-dependent degradation of p21

    Corinne Cayrol;Bernard Ducommun

  • Short and long time effects of low temperature Plasma Activated Media on 3D multicellular tumor spheroids.

    Florian Judée;Céline Fongia;Céline Fongia;Bernard Ducommun;Mohammed Yousfi

  • CDC25B phosphorylation by Aurora-A occurs at the G2/M transition and is inhibited by DNA damage.

    Martine Cazales;Estelle Schmitt;Emilie Montembault;Christine Dozier

  • Cell cycle control by the CDC25 phosphatases.

    Bernadette Aressy;Bernard Ducommun

  • Mechanism of Inhibition of Proliferating Cell Nuclear Antigen-Dependent DNA Synthesis by the Cyclin-Dependent Kinase Inhibitor p21

    Podust Vn;Podust Lm;Goubin F;Ducommun B

  • Regulation of CDC25B phosphatases subcellular localization

    Noélie Davezac;Véronique Baldin;Brian Gabrielli;Alistair Forrest

  • Multicellular tumor spheroid model to evaluate spatio-temporal dynamics effect of chemotherapeutics: application to the gemcitabine/CHK1 inhibitor combination in pancreatic cancer

    Isabelle Dufau;Céline Frongia;Flavie Sicard;Laure Dedieu

  • Multicellular tumor spheroid models to explore cell cycle checkpoints in 3D

    Jennifer Laurent;Jennifer Laurent;Céline Frongia;Céline Frongia;Martine Cazales;Martine Cazales;Odile Mondesert;Odile Mondesert

  • Phosphorylation of Human CDC25B Phosphatase by CDK1-Cyclin A Triggers Its Proteasome-dependent Degradation

    Véronique Baldin;Christophe Cans;Martine Knibiehler;Bernard Ducommun

Frequent Co-Authors

Bernard Monsarrat
Bernard Monsarrat Federal University of Toulouse Midi-Pyrénées
Guy Lenaers
Guy Lenaers University of Angers
Odile Burlet-Schiltz
Odile Burlet-Schiltz Federal University of Toulouse Midi-Pyrénées
Giulio Draetta
Giulio Draetta The University of Texas MD Anderson Cancer Center
Claude Prigent
Claude Prigent University of Rennes
Jean-Christophe Bourdon
Jean-Christophe Bourdon University of Dundee
Brian Gabrielli
Brian Gabrielli University of Queensland
Nohad Gresh
Nohad Gresh Centre national de la recherche scientifique, CNRS
Josseline Kaplan
Josseline Kaplan Université Paris Cité

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