2026 David C. Chan: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	79	1020	906	537	467	148	58480

Overview

David C. Chan is affiliated with the California Institute of Technology in the United States. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with additional work in medicine. Key subfields of study include molecular biology, epidemiology, clinical biochemistry, cell biology, and cellular and molecular neuroscience.

The scientist's research focuses on several main topics:

Mitochondrial Function and Pathology
ATP Synthase and ATPases Research
Autophagy in Disease and Therapy
Metabolism and Genetic Disorders
Endoplasmic Reticulum Stress and Disease
Neuroscience and Neuropharmacology Research
Photosynthetic Processes and Mechanisms

Frequent publication venues include Nature Communications, bioRxiv (Cold Spring Harbor Laboratory), Molecular Cell, Communications Biology, and Molecular Neurodegeneration.

Selected recent publications by David C. Chan include:

Mitophagy mediated by BNIP3 and NIX protects against ferroptosis by downregulating mitochondrial reactive oxygen species, 2024, Cell Death and Differentiation
Solving neurodegeneration: common mechanisms and strategies for new treatments, 2022, Molecular Neurodegeneration
LONP1 and mtHSP70 cooperate to promote mitochondrial protein folding, 2021, Nature Communications
Mitochondrial dynamics during spermatogenesis, 2020, Journal of Cell Science
Identification of new OPA1 cleavage site reveals that short isoforms regulate mitochondrial fusion, 2020, Molecular Biology of the Cell

David C. Chan frequently collaborates with other researchers in the field. Notable coauthors include Hsiuchen Chen, Chun-Shik Shin, Shun-ichi Yamashita, Tomotake Kanki, and Grigor Varuzhanyan.

Best Publications

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

8665
Citations
Core structure of GP41 from the HIV envelope glycoprotein

David C. Chan;Deborah Fass;Min Lu;James M. Berger

3222
Citations
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

Hsiuchen Chen;Scott A. Detmer;Andrew J. Ewald;Erik E. Griffin

2855
Citations
Mitochondria: Dynamic Organelles in Disease, Aging, and Development

David C. Chan

2744
Citations
HIV Entry and Its Inhibition

David C Chan;Peter S Kim

1956
Citations
Mitochondrial dynamics–fusion, fission, movement, and mitophagy–in neurodegenerative diseases

Hsiuchen Chen;David C. Chan

1911
Citations
Disruption of Fusion Results in Mitochondrial Heterogeneity and Dysfunction

Hsiuchen Chen;Anne Chomyn;David C. Chan

1813
Citations
Functions and dysfunctions of mitochondrial dynamics.

Scott A. Detmer;David C. Chan

1809
Citations
Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health

David C. Chan

1438
Citations
Mitochondrial Fusion and Fission in Mammals

David C. Chan

1313
Citations
Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

Oliver C. Losón;Zhiyin Song;Hsiuchen Chen;David C. Chan

1311
Citations
Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations.

Hsiuchen Chen;Marc Vermulst;Yun E. Wang;Anne Chomyn

1289
Citations
Structural basis of mitochondrial tethering by mitofusin complexes.

Takumi Koshiba;Scott A. Detmer;Jens T. Kaiser;Jens T. Kaiser;Hsiuchen Chen

1107
Citations
Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy

Nickie C. Chan;Anna M. Salazar;Anh H Pham;Michael J. Sweredoski

1048
Citations
OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L

Zhiyin Song;Hsiuchen Chen;Maja Fiket;Christiane Alexander

1034
Citations
Mitochondrial Fusion Protects against Neurodegeneration in the Cerebellum

Hsiuchen Chen;J. Michael McCaffery;David C. Chan

1030
Citations
Mitochondrial Dynamics and Its Involvement in Disease

David C Chan

1005
Citations
AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

Erin Quan Toyama;Sébastien Herzig;Julien Courchet;Tommy L. Lewis

968
Citations
Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the SId mutant

John G. Flanagan;David C. Chan;Philip Leder

949
Citations
Metabolic regulation of mitochondrial dynamics

Prashant Mishra;David C. Chan

928
Citations

Frequent Co-Authors

Philip Leder Harvard University

J. Michael McCaffery Johns Hopkins University

Valerio Carelli University of Bologna

Sonja Hess AstraZeneca (United Kingdom)

Christine E. Seidman Harvard University

David K. Ann City Of Hope National Medical Center

Andrea Ballabio Baylor College of Medicine

Richard J. Youle National Institutes of Health

Myung-Shik Lee Yonsei University

Mark R. Cookson National Institutes of Health

External Links

Personal website of David C. Chan

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