David C. Chan spends much of his time researching Cell biology, mitochondrial fusion, Mitochondrion, Mitochondrial fission and MFN2. His work deals with themes such as Glycoprotein and Mitophagy, Mitochondrial Degradation, which intersect with Cell biology. Mitochondrial fusion is closely attributed to Function in his work.
His work carried out in the field of Mitochondrion brings together such families of science as DNAJA3, Neuronal disease, Organelle and Mitochondrial DNA. His Mitochondrial fission research focuses on Mitochondrial fission factor and how it relates to ATP–ADP translocase. His MFN2 research integrates issues from Optic Atrophy 1 and Mitochondrial membrane fusion.
Cell biology, Mitochondrion, mitochondrial fusion, Mitochondrial fission and Genetics are his primary areas of study. The study incorporates disciplines such as Mitochondrial carrier, Mitophagy and FIS1 in addition to Cell biology. His study looks at the relationship between Mitochondrion and topics such as Cancer cell, which overlap with Downregulation and upregulation.
In his study, Coiled coil is strongly linked to Lipid bilayer fusion, which falls under the umbrella field of mitochondrial fusion. His Mitochondrial fission research is multidisciplinary, incorporating elements of Receptor, Mitochondrial apoptosis-induced channel, ATP–ADP translocase and Mitochondrial fission factor. In general Genetics, his work in Mitochondrial DNA, Gene and Gene isoform is often linked to SH3 domain linking many areas of study.
David C. Chan focuses on Cell biology, mitochondrial fusion, Mitochondrion, Mitophagy and GTPase. His Cell biology research focuses on Mitochondrial biogenesis in particular. His work in the fields of mitochondrial fusion, such as MFN1 and MFN2, overlaps with other areas such as Fission.
His Mitochondrial fission study, which is part of a larger body of work in Mitochondrion, is frequently linked to HSP60, bridging the gap between disciplines. His work in Mitophagy addresses subjects such as FIS1, which are connected to disciplines such as Bioinformatics, Text mining, Thioredoxin and microRNA. His GTPase research incorporates elements of Endoplasmic reticulum and Gene isoform.
His primary areas of study are Cell biology, mitochondrial fusion, Mitophagy, Mitochondrion and MFN1. His Cell biology study combines topics from a wide range of disciplines, such as Regulator and Transcriptome. His Mitophagy research is multidisciplinary, incorporating perspectives in Cytosol, Biophysics, EF hand and Mitochondrial fission.
His research integrates issues of Calcium and Neurodegeneration in his study of Mitochondrial fission. His biological study spans a wide range of topics, including Parkin, PINK1 and Programmed cell death. David C. Chan combines subjects such as GTPase, Mutation, Protein domain, MFN2 and Mitofusin-2 with his study of MFN1.
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Guidelines for the use and interpretation of assays for monitoring autophagy
Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham.
Core structure of GP41 from the HIV envelope glycoprotein
David C. Chan;Deborah Fass;Min Lu;James M. Berger.
Mitochondria: Dynamic Organelles in Disease, Aging, and Development
David C. Chan.
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
Hsiuchen Chen;Scott A. Detmer;Andrew J. Ewald;Erik E. Griffin.
Journal of Cell Biology (2003)
HIV Entry and Its Inhibition
David C Chan;Peter S Kim.
Mitochondrial dynamics–fusion, fission, movement, and mitophagy–in neurodegenerative diseases
Hsiuchen Chen;David C. Chan.
Human Molecular Genetics (2009)
Disruption of Fusion Results in Mitochondrial Heterogeneity and Dysfunction
Hsiuchen Chen;Anne Chomyn;David C. Chan.
Journal of Biological Chemistry (2005)
Functions and dysfunctions of mitochondrial dynamics.
Scott A. Detmer;David C. Chan.
Nature Reviews Molecular Cell Biology (2007)
Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health
David C. Chan.
Annual Review of Genetics (2012)
Mitochondrial Fusion and Fission in Mammals
David C. Chan.
Annual Review of Cell and Developmental Biology (2006)
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