Yuxian He

Overview

Best Publications

• Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China.

  Y. Guan;B. J. Zheng;Y. Q. He;X. L. Liu

  2911
  Citations

• The spike protein of SARS-CoV — a target for vaccine and therapeutic development

  Lanying Du;Yuxian He;Yusen Zhou;Shuwen Liu

  1860
  Citations

• Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response

  Ilona Glowacka;Stephanie Bertram;Marcel A. Müller;Paul Allen

  1197
  Citations

• Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy.

  Linqi Zhang;B. Ramratnam;K. Tenner-Racz;Yuxian He

  998
  Citations

• Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy.

  Hongjing Gu;Qi Chen;Guan Yang;Lei He

  762
  Citations

• Interaction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: implications for virus fusogenic mechanism and identification of fusion inhibitors.

  Shuwen Liu;Gengfu Xiao;Yibang Chen;Yuxian He

  685
  Citations

• Receptor-binding domain of SARS-CoV spike protein induces highly potent neutralizing antibodies: implication for developing subunit vaccine.

  Yuxian He;Yusen Zhou;Shuwen Liu;Zhihua Kou

  472
  Citations

• Measuring recent thymic emigrants in blood of normal and HIV-1-infected individuals before and after effective therapy.

  Linqi Zhang;Sharon R. Lewin;Martin Markowitz;Hsi-Hsun Lin

  433
  Citations

• IFITM proteins restrict viral membrane hemifusion

  Kun Li;Ruben M. Markosyan;Yi-Min Zheng;Ottavia Golfetto

  430
  Citations

• The V1/V2 domain of gp120 is a global regulator of the sensitivity of primary human immunodeficiency virus type 1 isolates to neutralization by antibodies commonly induced upon infection.

  Abraham Pinter;William J. Honnen;Yuxian He;Miroslaw K. Gorny

  370
  Citations

• Receptor-binding domain of severe acute respiratory syndrome coronavirus spike protein contains multiple conformation-dependent epitopes that induce highly potent neutralizing antibodies.

  Yuxian He;Hong Lu;Pamela Siddiqui;Yusen Zhou

  352
  Citations

• Cleavage and Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein by Human Airway Trypsin-Like Protease

  Stephanie Bertram;Ilona Glowacka;Marcel A. Müller;Hayley Lavender

  348
  Citations

• Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies

  Zhongyu Zhu;Samitabh Chakraborti;Yuxian He;Anjeanette Roberts

  339
  Citations

• N-Substituted Pyrrole Derivatives as Novel Human Immunodeficiency Virus Type 1 Entry Inhibitors That Interfere with the gp41 Six-Helix Bundle Formation and Block Virus Fusion

  Shibo Jiang;Hong Lu;Shuwen Liu;Qian Zhao

  337
  Citations

• Identification of N-phenyl-N′-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4

  Qian Zhao;Liying Ma;Shibo Jiang;Hong Lu

  266
  Citations

• Theaflavin derivatives in black tea and catechin derivatives in green tea inhibit HIV-1 entry by targeting gp41.

  Shuwen Liu;Hong Lu;Qian Zhao;Yuxian He

  250
  Citations

• SARS vaccine development.

  Shibo Jiang;Yuxian He;Shuwen Liu

  247
  Citations

• Design of Potent Membrane Fusion Inhibitors against SARS-CoV-2, an Emerging Coronavirus with High Fusogenic Activity.

  Yuanmei Zhu;Danwei Yu;Hongxia Yan;Huihui Chong

  247
  Citations

• Receptor-binding domain of SARS-CoV spike protein induces long-term protective immunity in an animal model.

  Lanying Du;Guangyu Zhao;Yuxian He;Yan Guo

  234
  Citations

• Design and Evaluation of Sifuvirtide, a Novel HIV-1 Fusion Inhibitor

  Yuxian He;Yuxian He;Yonghong Xiao;Haifeng Song;Qing Liang

  219
  Citations