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Immunology

D-Index
95
Citations
32841
World Ranking
899
National Ranking
500

Medicine

D-Index
95
Citations
32808
World Ranking
10076
National Ranking
5189

Overview

Dimiter S. Dimitrov is affiliated with the University of Pittsburgh in the United States. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, with a notable focus on oncology, infectious diseases, and immunology.

The scientist's prominent research topics include:

  • CAR-T cell therapy research
  • Monoclonal and Polyclonal Antibodies Research
  • SARS-CoV-2 and COVID-19 Research
  • Neuroblastoma Research and Treatments
  • Immune Cell Function and Interaction
  • Virus-based gene therapy research
  • Immunotherapy and Immune Responses

Dimiter S. Dimitrov's recent papers demonstrate a diverse involvement in cutting-edge biomedical research. Key publications include:

  • "Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies," 2021, PLoS Biology
  • "Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies," 2020, Cancer Cell
  • "GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity," 2021, Cancer Cell
  • "Trispecific CD19-CD20-CD22-targeting duoCAR-T cells eliminate antigen-heterogeneous B cell tumors in preclinical models," 2021, Science Translational Medicine
  • "Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study," 2020, The Lancet Infectious Diseases

Frequent co-authors who have collaborated extensively with Dimiter S. Dimitrov include:

  • Wei Li (38 publications)
  • John W. Mellors (28 publications)
  • Zehua Sun (23 publications)
  • Poul H. Sorensen (17 publications)
  • Rimas J. Orentas (15 publications)

Dimitrov's work has been published repeatedly in a range of scientific venues. The most common publication venues include:

  • Cancer Research (17 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (9 publications)
  • Nature Communications (6 publications)
  • UNC Libraries (4 publications)
  • Regular and Young Investigator Award Abstracts (4 publications)

The main fields of study for Dimitrov's research articles are medicine with 197 publications and biochemistry, genetics, and molecular biology with 61 publications. Subfields with significant volume of research output include oncology, radiology and nuclear medicine, molecular biology, infectious diseases, and immunology.

Best Publications

  • CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy.

    Terry J Fry;Nirali N Shah;Rimas J Orentas;Maryalice Stetler-Stevenson

  • Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition

    Leonid Cherkassky;Aurore Morello;Jonathan Villena-Vargas;Yang Feng

  • HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression

    Richard T. Davey;Niranjan Bhat;Christian Yoder;Tae Wook Chun

  • Structural definition of a conserved neutralization epitope on HIV-1 gp120.

    Tongqing Zhou;Ling Xu;Barna Dey;Ann J. Hessell

  • Structure of a V3-Containing HIV-1 gp120 Core

    Chih-chin Huang;Min Tang;Mei-Yun Zhang;Shahzad Majeed

  • Evaluation of gene expression measurements from commercial microarray platforms

    Paul K. Tan;Thomas J. Downey;Edward L. Spitznagel;Pin Xu

  • Virus entry: molecular mechanisms and biomedical applications

    Dimiter S. Dimitrov

  • Anti-CD22–chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia

    Waleed Haso;Daniel W. Lee;Nirali N. Shah;Maryalice Stetler-Stevenson

  • CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors.

    Robbie G. Majzner;Johanna L. Theruvath;Anandani Nellan;Sabine Heitzeneder

  • Quantitation of human immunodeficiency virus type 1 infection kinetics.

    D. S. Dimitrov;R. L. Willey;H. Sato;Lung-Ji Chang

  • Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia

    Masashi Shingai;Yoshiaki Nishimura;Florian Klein;Hugo Mouquet

  • Ephrin-B2 ligand is a functional receptor for Hendra virus and Nipah virus

    Matthew I. Bonaparte;Antony S. Dimitrov;Katharine N. Bossart;Gary Crameri

  • The SARS-CoV S glycoprotein: expression and functional characterization.

    Xiaodong Xiao;Samitabh Chakraborti;Anthony S Dimitrov;Kosi Gramatikoff

  • Evidence for Cell-Surface Association Between Fusin and the CD4-gp120 Complex in Human Cell Lines

    Cheryl K. Lapham;Jun Ouyang;Bhaskar Chandrasekhar;Nga Y. Nguyen

  • Distinctions Between CD8+ and CD4+ T-Cell Regenerative Pathways Result in Prolonged T-Cell Subset Imbalance After Intensive Chemotherapy

    Crystal L. Mackall;Thomas A. Fleisher;Thomas A. Fleisher;Margaret R. Brown;Margaret R. Brown;Mary P. Andrich;Mary P. Andrich

  • Access of Antibody Molecules to the Conserved Coreceptor Binding Site on Glycoprotein gp120 Is Sterically Restricted on Primary Human Immunodeficiency Virus Type 1

    Aran F. Labrijn;Pascal Poignard;Aarti Raja;Michael B. Zwick

  • Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature

    Steven Seaman;Zhongyu Zhu;Saurabh Saha;Xiaoyan M. Zhang

  • Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.

    Lei Chen;Young Do Kwon;Tongqing Zhou;Xueling Wu

  • Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: implications for evasion of immune responses and design of vaccine immunogens.

    Xiaodong Xiao;Weizao Chen;Yang Feng;Zhongyu Zhu

  • A neutralizing human monoclonal antibody protects against lethal disease in a new ferret model of acute nipah virus infection.

    Katharine N. Bossart;Zhongyu Zhu;Deborah Middleton;Jessica Klippel

  • Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120

    Chih-chin Huang;Miro Venturi;Shahzad Majeed;Michael J. Moore

  • Cell-to-cell spread of HIV-1 occurs within minutes and may not involve the participation of virus particles

    Hironori Sato;Jan Orensteint;Dimiter Dimitrov;Malcolm Martin

Frequent Co-Authors

Christopher C. Broder
Christopher C. Broder Uniformed Services University of the Health Sciences
Tianlei Ying
Tianlei Ying Fudan University
Dennis R. Burton
Dennis R. Burton Scripps Research Institute
Richard T. Wyatt
Richard T. Wyatt Scripps Research Institute
Peter D. Kwong
Peter D. Kwong Columbia University Medical Center
Shibo Jiang
Shibo Jiang Fudan University
Robert Blumenthal
Robert Blumenthal University of Toledo
Joseph Sodroski
Joseph Sodroski Harvard Medical School
Tongqing Zhou
Tongqing Zhou National Institutes of Health
Michael B. Zwick
Michael B. Zwick Scripps Research Institute

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