Nigel Bourne mainly investigates Virology, Virus, Herpes simplex virus, Immunology and Herpesviridae. His work investigates the relationship between Virology and topics such as Caviidae that intersect with problems in Congenital cytomegalovirus infection and Betaherpesvirinae. His work in the fields of Vero cell overlaps with other areas such as Biological activity.
In general Herpes simplex virus, his work in Herpes Genitalis is often linked to Microbicides for sexually transmitted diseases linking many areas of study. His Vaccination study which covers Alphaherpesvirinae that intersects with Immunization, Mucosal Infection and Antigen. His study in the field of NS5B is also linked to topics like Replicon.
His scientific interests lie mostly in Virology, Virus, Immunology, Herpes simplex virus and Herpesviridae. His studies deal with areas such as Disease and Immunization, Immune system as well as Virology. His study on Viral disease, Hepatitis C virus and Viremia is often connected to Microbicides for sexually transmitted diseases as part of broader study in Virus.
His work on Herpes Genitalis as part of general Herpes simplex virus research is frequently linked to Sexually transmitted disease, thereby connecting diverse disciplines of science. As part of the same scientific family, Nigel Bourne usually focuses on Herpesviridae, concentrating on Vaccination and intersecting with Herpes Simplex Virus Vaccines. Nigel Bourne focuses mostly in the field of Flavivirus, narrowing it down to topics relating to Zika virus and, in certain cases, Transmission.
His primary areas of study are Virology, Immunology, Immunity, Virus and Dengue fever. His Disease research extends to the thematically linked field of Virology. His work on Immunology deals in particular with Viral shedding, Herpes simplex virus, Viral load, Proinflammatory cytokine and Spleen.
His research investigates the connection between Immunity and topics such as Pathogenesis that intersect with issues in Foreskin and Interferon. Nigel Bourne is interested in Hepatitis C virus, which is a branch of Virus. His Dengue fever research is multidisciplinary, incorporating perspectives in Receptor and Alpha interferon.
Nigel Bourne focuses on Virology, Dengue virus, Dengue fever, Immunology and Viremia. His Virology research incorporates themes from Complementary DNA, Genotype and Virulence. His Dengue virus research includes themes of Receptor and Disease.
His study in Viral load and Immunity is done as part of Immunology. His Viremia study improves the overall literature in Virus. His Dengue vaccine research includes elements of Antibody, Neutralizing antibody, Immune system, Immunogenicity and Viral disease.
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T lymphocytes are required for protection of the vaginal mucosae and sensory ganglia of immune mice against reinfection with herpes simplex virus type 2
Gregg N. Milligan;David I. Bernstein;Nigel Bourne.
Journal of Immunology (1998)
Dendrimers, a New Class of Candidate Topical Microbicides with Activity against Herpes Simplex Virus Infection
Nigel Bourne;L. R. Stanberry;E. R. Kern;G. Holan.
Antimicrobial Agents and Chemotherapy (2000)
An Infectious cDNA Clone of Zika Virus to Study Viral Virulence, Mosquito Transmission, and Antiviral Inhibitors
Chao Shan;Xuping Xie;Antonio E. Muruato;Shannan L. Rossi.
Cell Host & Microbe (2016)
Multiple effects of silymarin on the hepatitis C virus lifecycle.
Jessica Wagoner;Amina Negash;Olivia J Kane;Laura E Martinez.
Hepatology (2010)
DNA Immunization against Experimental Genital Herpes Simplex Virus Infection
Nigel Bourne;Lawrence R. Stanberry;David I. Bernstein;Denise Lew.
The Journal of Infectious Diseases (1996)
Plant products as topical microbicide candidates: Assessment of in vitro and in vivo activity against herpes simplex virus type 2
Krystyn Z. Bourne;Nigel Bourne;Shirley F. Reising;Lawrence R. Stanberry.
Antiviral Research (1999)
PSI-7851, a Pronucleotide of β-d-2′-Deoxy-2′-Fluoro-2′-C-Methyluridine Monophosphate, Is a Potent and Pan-Genotype Inhibitor of Hepatitis C Virus Replication
Angela M. Lam;Eisuke Murakami;Christine Espiritu;Holly M. Micolochick Steuer.
Antimicrobial Agents and Chemotherapy (2010)
Herpes Simplex Virus (HSV) Type 2 Glycoprotein D Subunit Vaccines and Protection against Genital HSV-1 or HSV-2 Disease in Guinea Pigs
Nigel Bourne;Fernando J Bravo;Myriam Francotte;David I Bernstein.
The Journal of Infectious Diseases (2003)
Evaluations of Unformulated and Formulated Dendrimer-Based Microbicide Candidates in Mouse and Guinea Pig Models of Genital Herpes
D. I. Bernstein;L. R. Stanberry;L. R. Stanberry;S. Sacks;N. K. Ayisi.
Antimicrobial Agents and Chemotherapy (2003)
Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations.
Min Kyung Yi;Xiao Tong;Angela Skelton;Robert Chase.
Journal of Biological Chemistry (2006)
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