D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 43 Citations 5,721 104 World Ranking 4174 National Ranking 1635

Overview

What is he best known for?

The fields of study he is best known for:

  • Virus
  • Gene
  • DNA

Nigel Bourne mainly investigates Virology, Virus, Herpes simplex virus, Immunology and Herpesviridae. His work investigates the relationship between Virology and topics such as Caviidae that intersect with problems in Congenital cytomegalovirus infection and Betaherpesvirinae. His work in the fields of Vero cell overlaps with other areas such as Biological activity.

In general Herpes simplex virus, his work in Herpes Genitalis is often linked to Microbicides for sexually transmitted diseases linking many areas of study. His Vaccination study which covers Alphaherpesvirinae that intersects with Immunization, Mucosal Infection and Antigen. His study in the field of NS5B is also linked to topics like Replicon.

His most cited work include:

  • T lymphocytes are required for protection of the vaginal mucosae and sensory ganglia of immune mice against reinfection with herpes simplex virus type 2 (190 citations)
  • An Infectious cDNA Clone of Zika Virus to Study Viral Virulence, Mosquito Transmission, and Antiviral Inhibitors (184 citations)
  • Dendrimers, a New Class of Candidate Topical Microbicides with Activity against Herpes Simplex Virus Infection (167 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Virology, Virus, Immunology, Herpes simplex virus and Herpesviridae. His studies deal with areas such as Disease and Immunization, Immune system as well as Virology. His study on Viral disease, Hepatitis C virus and Viremia is often connected to Microbicides for sexually transmitted diseases as part of broader study in Virus.

His work on Herpes Genitalis as part of general Herpes simplex virus research is frequently linked to Sexually transmitted disease, thereby connecting diverse disciplines of science. As part of the same scientific family, Nigel Bourne usually focuses on Herpesviridae, concentrating on Vaccination and intersecting with Herpes Simplex Virus Vaccines. Nigel Bourne focuses mostly in the field of Flavivirus, narrowing it down to topics relating to Zika virus and, in certain cases, Transmission.

He most often published in these fields:

  • Virology (78.33%)
  • Virus (55.00%)
  • Immunology (45.83%)

What were the highlights of his more recent work (between 2012-2020)?

  • Virology (78.33%)
  • Immunology (45.83%)
  • Immunity (10.83%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Virology, Immunology, Immunity, Virus and Dengue fever. His Disease research extends to the thematically linked field of Virology. His work on Immunology deals in particular with Viral shedding, Herpes simplex virus, Viral load, Proinflammatory cytokine and Spleen.

His research investigates the connection between Immunity and topics such as Pathogenesis that intersect with issues in Foreskin and Interferon. Nigel Bourne is interested in Hepatitis C virus, which is a branch of Virus. His Dengue fever research is multidisciplinary, incorporating perspectives in Receptor and Alpha interferon.

Between 2012 and 2020, his most popular works were:

  • An Infectious cDNA Clone of Zika Virus to Study Viral Virulence, Mosquito Transmission, and Antiviral Inhibitors (184 citations)
  • The fibroblast growth factor 14·voltage-gated sodium channel complex is a new target of glycogen synthase kinase 3 (GSK3) (63 citations)
  • A Lethal Murine Infection Model for Dengue Virus 3 in AG129 Mice Deficient in Type I and II Interferon Receptors Leads to Systemic Disease (48 citations)

In his most recent research, the most cited papers focused on:

  • Virus
  • Gene
  • DNA

Nigel Bourne focuses on Virology, Dengue virus, Dengue fever, Immunology and Viremia. His Virology research incorporates themes from Complementary DNA, Genotype and Virulence. His Dengue virus research includes themes of Receptor and Disease.

His study in Viral load and Immunity is done as part of Immunology. His Viremia study improves the overall literature in Virus. His Dengue vaccine research includes elements of Antibody, Neutralizing antibody, Immune system, Immunogenicity and Viral disease.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

T lymphocytes are required for protection of the vaginal mucosae and sensory ganglia of immune mice against reinfection with herpes simplex virus type 2

Gregg N. Milligan;David I. Bernstein;Nigel Bourne.
Journal of Immunology (1998)

291 Citations

Dendrimers, a New Class of Candidate Topical Microbicides with Activity against Herpes Simplex Virus Infection

Nigel Bourne;L. R. Stanberry;E. R. Kern;G. Holan.
Antimicrobial Agents and Chemotherapy (2000)

267 Citations

An Infectious cDNA Clone of Zika Virus to Study Viral Virulence, Mosquito Transmission, and Antiviral Inhibitors

Chao Shan;Xuping Xie;Antonio E. Muruato;Shannan L. Rossi.
Cell Host & Microbe (2016)

260 Citations

Multiple effects of silymarin on the hepatitis C virus lifecycle.

Jessica Wagoner;Amina Negash;Olivia J Kane;Laura E Martinez.
Hepatology (2010)

259 Citations

DNA Immunization against Experimental Genital Herpes Simplex Virus Infection

Nigel Bourne;Lawrence R. Stanberry;David I. Bernstein;Denise Lew.
The Journal of Infectious Diseases (1996)

228 Citations

Plant products as topical microbicide candidates: Assessment of in vitro and in vivo activity against herpes simplex virus type 2

Krystyn Z. Bourne;Nigel Bourne;Shirley F. Reising;Lawrence R. Stanberry.
Antiviral Research (1999)

209 Citations

PSI-7851, a Pronucleotide of β-d-2′-Deoxy-2′-Fluoro-2′-C-Methyluridine Monophosphate, Is a Potent and Pan-Genotype Inhibitor of Hepatitis C Virus Replication

Angela M. Lam;Eisuke Murakami;Christine Espiritu;Holly M. Micolochick Steuer.
Antimicrobial Agents and Chemotherapy (2010)

188 Citations

Herpes Simplex Virus (HSV) Type 2 Glycoprotein D Subunit Vaccines and Protection against Genital HSV-1 or HSV-2 Disease in Guinea Pigs

Nigel Bourne;Fernando J Bravo;Myriam Francotte;David I Bernstein.
The Journal of Infectious Diseases (2003)

164 Citations

Evaluations of Unformulated and Formulated Dendrimer-Based Microbicide Candidates in Mouse and Guinea Pig Models of Genital Herpes

D. I. Bernstein;L. R. Stanberry;L. R. Stanberry;S. Sacks;N. K. Ayisi.
Antimicrobial Agents and Chemotherapy (2003)

153 Citations

Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations.

Min Kyung Yi;Xiao Tong;Angela Skelton;Robert Chase.
Journal of Biological Chemistry (2006)

138 Citations

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