What is he best known for?
The fields of study he is best known for:
David M. Knipe mainly focuses on Virology, Herpes simplex virus, Molecular biology, Virus and Viral replication.
Within one scientific family, David M. Knipe focuses on topics pertaining to Innate immune system under Virology, and may sometimes address concerns connected to Proinflammatory cytokine.
The concepts of his Herpes simplex virus study are interwoven with issues in Plasmid and Recombinant DNA.
His work carried out in the field of Molecular biology brings together such families of science as Regulation of gene expression, Immediate early protein, Gene expression, ICP8 and Mutant.
The subject of his Virus research is within the realm of Genetics.
His study looks at the intersection of Viral replication and topics like Immunization with Nasal administration and Virulence.
His most cited work include:
- Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis. (527 citations)
- An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection (369 citations)
- Vaginal Submucosal Dendritic Cells, but Not Langerhans Cells, Induce Protective Th1 Responses to Herpes Simplex Virus-2 (358 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Virology, Herpes simplex virus, Virus, Molecular biology and Viral replication.
The Virology study combines topics in areas such as Immunology and Immune system.
His work deals with themes such as Immediate early protein, Mutant, Gene, Cell biology and Innate immune system, which intersect with Herpes simplex virus.
His Cell biology study combines topics from a wide range of disciplines, such as Chromatin and Transcription.
Virus is frequently linked to Immunogenicity in his study.
His studies deal with areas such as Gene expression, ICP8, DNA, Cell nucleus and Single-stranded binding protein as well as Molecular biology.
He most often published in these fields:
- Virology (54.41%)
- Herpes simplex virus (52.21%)
- Virus (36.40%)
What were the highlights of his more recent work (between 2011-2021)?
- Virology (54.41%)
- Herpes simplex virus (52.21%)
- Cell biology (15.81%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Virology, Herpes simplex virus, Cell biology, Virus and Viral replication.
His research in Virology tackles topics such as Genome which are related to areas like Peptide sequence.
His research in Herpes simplex virus intersects with topics in Chromatin, Gene and Innate immune system.
His biological study spans a wide range of topics, including Death-associated protein 6, Heterochromatin, Gene silencing and Cell.
His studies in Virus integrate themes in fields like genomic DNA, Ubiquitin ligase, Sequence analysis and IRF3.
His Viral replication research integrates issues from Recombinant virus, Transcription and DNA, DNA replication.
Between 2011 and 2021, his most popular works were:
- Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein (304 citations)
- A Promiscuous Lipid-Binding Protein Diversifies the Subcellular Sites of Toll-like Receptor Signal Transduction (163 citations)
- cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection (142 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Herpes simplex virus, Virology, Cell biology, Innate immune system and Molecular biology.
His study in Herpes simplex virus is interdisciplinary in nature, drawing from both genomic DNA, TLR2, Transfection and IFI16.
The Viral replication and Virus research he does as part of his general Virology study is frequently linked to other disciplines of science, such as Synonymous substitution, therefore creating a link between diverse domains of science.
David M. Knipe has researched Cell biology in several fields, including Chromatin, Genetics, Gene silencing and Gene.
His Innate immune system research incorporates themes from Nuclear localization sequence and Cell type.
His research integrates issues of Conserved sequence, Mutant protein, Mutant and Single-stranded binding protein in his study of Molecular biology.
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