World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
98
Citations
27666
World Ranking
465
National Ranking
214

Medicine

D-Index
98
Citations
27666
World Ranking
9034
National Ranking
4655

Overview

David M. Knipe is affiliated with Harvard University in the United States. Their research primarily spans the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Within these broad areas, their work has substantial focus on subfields such as Epidemiology, Immunology, Infectious Diseases, Genetics, and Molecular Biology.

The main topics covered by this scientist include:

  • Herpesvirus Infections and Treatments
  • Virus-based gene therapy research
  • Interferon and immune responses
  • RNA regulation and disease
  • SARS-CoV-2 and COVID-19 Research
  • Animal Virus Infections Studies
  • Cytomegalovirus and herpesvirus research

Their publication record includes recent papers such as:

  • "Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1 latency", 2021, Nature Microbiology
  • "A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV-2 at the immune-epithelial interface", 2021, Proceedings of the National Academy of Sciences
  • "Vesicular Stomatitis Virus Chimeras Expressing the Oropouche Virus Glycoproteins Elicit Protective Immune Responses in Mice", 2021, mBio
  • "Ensuring vaccine safety", 2020, Science
  • "Replication Compartments of Eukaryotic and Bacterial DNA Viruses: Common Themes Between Different Domains of Host Cells", 2022, Annual Review of Virology

Frequent co-authors collaborating with this scientist include:

  • Hyung Suk Oh (14 publications)
  • George M. Church (6 publications)
  • David A. Leib (6 publications)
  • Jean M. Pesola (5 publications)
  • Donald M. Coen (5 publications)

Their work has been frequently published in venues such as:

  • mBio (5 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (4 publications)
  • Proceedings of the National Academy of Sciences (3 publications)
  • PLoS Pathogens (3 publications)
  • Virology (3 publications)

Best Publications

  • Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis.

    Evelyn A. Kurt-Jones;Melvin Chan;Shenghua Zhou;Jennifer P. Wang

  • An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection

    Deborah Palliser;Dipanjan Chowdhury;Qing Yin Wang;Sandra J. Lee

  • Chromatin control of herpes simplex virus lytic and latent infection

    David M. Knipe;Anna Cliffe

  • Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein

    Megan H. Orzalli;Neal A. DeLuca;David M. Knipe

  • Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate

    Donald M. Coen;Magdalena Kosz-Vnenchak;Jennie G. Jacobson;David A. Leib

  • Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency.

    D A Leib;D M Coen;C L Bogard;K A Hicks

  • Functions of Cytoplasmic Fibers in Non-Muscle Cell Motility

    Robert D. Goldman;David M. Knipe

  • Vaginal Submucosal Dendritic Cells, but Not Langerhans Cells, Induce Protective Th1 Responses to Herpes Simplex Virus-2

    Xinyan Zhao;Eszter Deak;Kelly A. Soderberg;Melissa Linehan

  • A deletion mutant of the latency-associated transcript of herpes simplex virus type 1 reactivates from the latent state with reduced frequency

    D A Leib;C L Bogard;M Kosz-Vnenchak;K A Hicks

  • The intranuclear location of a herpes simplex virus DNA-binding protein is determined by the status of viral DNA replication

    Margaret P. Quinlan;Lan Bo Chen;David M. Knipe

  • Formation of DNA replication structures in herpes virus-infected cells requires a viral DNA binding protein

    Anne de Bruyn Kops;David M. Knipe

  • Molecular genetics of herpes simplex virus. VII. Characterization of a temperature-sensitive mutant produced by in vitro mutagenesis and defective in DNA synthesis and accumulation of gamma polypeptides.

    A J Conley;D M Knipe;P C Jones;B Roizman

  • Molecular Genetics of Herpes Simplex Virus II. Mapping of the Major Viral Glycoproteins and of the Genetic Loci Specifying the Social Behavior of Infected Cells

    William T. Ruyechan;Lawrence S. Morse;David M. Knipe;Bernard Roizman

  • Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27.

    Stephen A. Rice;David M. Knipe

  • Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lytic-gene promoters in latent infection.

    Qing-Yin Wang;Changhong Zhou;Karen E. Johnson;Robert C. Colgrove

  • Stimulation of expression of a herpes simplex virus DNA-binding protein by two viral functions.

    M P Quinlan;D M Knipe

  • Alternative mechanisms for activation of human immunodeficiency virus enhancer in T cells.

    Gary J. Nabel;Stephen A. Rice;David M. Knipe;David Baltimore

  • Transcription of the Herpes Simplex Virus Latency-Associated Transcript Promotes the Formation of Facultative Heterochromatin on Lytic Promoters

    Anna R. Cliffe;David A. Garber;David M. Knipe

  • Proteomics of Herpes Simplex Virus Replication Compartments: Association of Cellular DNA Replication, Repair, Recombination, and Chromatin Remodeling Proteins with ICP8

    Travis J. Taylor;David M. Knipe

  • A Promiscuous Lipid-Binding Protein Diversifies the Subcellular Sites of Toll-like Receptor Signal Transduction

    Kevin S. Bonham;Megan H. Orzalli;Kachiko Hayashi;Amaya I. Wolf

Frequent Co-Authors

Donald M. Coen
Donald M. Coen Harvard University
Hyung Suk Oh
Hyung Suk Oh Korea Institute of Science and Technology
Robert W. Finberg
Robert W. Finberg University of Massachusetts Chan Medical School
Evelyn A. Kurt-Jones
Evelyn A. Kurt-Jones University of Massachusetts Chan Medical School
Neal A. DeLuca
Neal A. DeLuca University of Pittsburgh
Mark A. Brockman
Mark A. Brockman Simon Fraser University
Priscilla A. Schaffer
Priscilla A. Schaffer Beth Israel Deaconess Medical Center
Bernard Roizman
Bernard Roizman University of Chicago
Katherine A. Fitzgerald
Katherine A. Fitzgerald University of Massachusetts Chan Medical School

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