Bo-Jian Zheng

Research.com Recognitions

• 2026 - Research.com Immunology in China Leader Award

Overview

Best Publications

• Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study.

  J S M Peiris;C M Chu;V C C Cheng;K S Chan

  3003
  Citations

• Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China.

  Y. Guan;B. J. Zheng;Y. Q. He;X. L. Liu

  2911
  Citations

• Discovery of Seven Novel Mammalian and Avian Coronaviruses in the Genus Deltacoronavirus Supports Bat Coronaviruses as the Gene Source of Alphacoronavirus and Betacoronavirus and Avian Coronaviruses as the Gene Source of Gammacoronavirus and Deltacoronavirus

  Patrick C. Y. Woo;Susanna K. P. Lau;Carol S. F. Lam;Candy C. Y. Lau

  1933
  Citations

• Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People's Republic of China, in February, 2003

  N. S. Zhong;B. J. Zheng;Y. M. Li;L. L. M. Poon

  1868
  Citations

• The spike protein of SARS-CoV — a target for vaccine and therapeutic development

  Lanying Du;Yuxian He;Yusen Zhou;Shuwen Liu

  1860
  Citations

• Identification and characterization of tumorigenic liver cancer stem/progenitor cells.

  Stephanie Ma;Kwok–Wah Chan;Liang Hu;Terence Kin–Wah Lee

  1572
  Citations

• Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque.

  Bao Jian Li;Qingquan Tang;Du Cheng;Chuan Qin

  621
  Citations

• Aldehyde Dehydrogenase Discriminates the CD133 Liver Cancer Stem Cell Populations

  Stephanie Ma;Kwok Wah Chan;Terence Kin-Wah Lee;Kwan Ho Tang

  592
  Citations

• Active Replication of Middle East Respiratory Syndrome Coronavirus and Aberrant Induction of Inflammatory Cytokines and Chemokines in Human Macrophages: Implications for Pathogenesis

  Jie Zhou;Hin Chu;Cun Li;Bosco Ho-Yin Wong

  545
  Citations

• Delayed Clearance of Viral Load and Marked Cytokine Activation in Severe Cases of Pandemic H1N1 2009 Influenza Virus Infection

  Kelvin K. W. To;Ivan F. N. Hung;Iris W. S. Li;Kar-Lung Lee

  503
  Citations

• Middle East Respiratory Syndrome Coronavirus Efficiently Infects Human Primary T Lymphocytes and Activates the Extrinsic and Intrinsic Apoptosis Pathways

  Hin Chu;Jie Zhou;Bosco Ho-Yin Wong;Cun Li

  473
  Citations

• miR-130b Promotes CD133+ Liver Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1

  Stephanie Ma;Kwan Ho Tang;Yuen Piu Chan;Terence K. Lee

  449
  Citations

• Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus.

  Jasper F.W. Chan;Kwok Hung Chan;Richard Y.T. Kao;Kelvin K.W. To

  435
  Citations

• Comparative Analysis of Twelve Genomes of Three Novel Group 2c and Group 2d Coronaviruses Reveals Unique Group and Subgroup Features

  Patrick C. Y. Woo;Ming Wang;Susanna K. P. Lau;Huifang Xu

  387
  Citations

• SARS-CoV infection in a restaurant from palm civet.

  Ming Wang;Meiying Yan;Huifang Xu;Weili Liang

  380
  Citations

• Delayed antiviral plus immunomodulator treatment still reduces mortality in mice infected by high inoculum of influenza A/H5N1 virus

  Bo-Jian Zheng;Kwok-Wah Chan;Yong-Ping Lin;Guang-Yu Zhao

  371
  Citations

• Ecoepidemiology and Complete Genome Comparison of Different Strains of Severe Acute Respiratory Syndrome-Related Rhinolophus Bat Coronavirus in China Reveal Bats as a Reservoir for Acute, Self-Limiting Infection That Allows Recombination Events

  Susanna K.P. Lau;Kenneth S.M. Li;Yi Huang;Chung Tong Shek

  371
  Citations

• Severe Acute Respiratory Syndrome Coronavirus M Protein Inhibits Type I Interferon Production by Impeding the Formation of TRAF3·TANK·TBK1/IKKϵ Complex

  Kam Leung Siu;Kin Hang Kok;Ming Him James Ng;Vincent K.M. Poon

  364
  Citations

• Severe acute respiratory syndrome-associated coronavirus 3a protein forms an ion channel and modulates virus release

  Wei Lu;Bo-Jian Zheng;Ke Xu;Wolfgang Schwarz

  351
  Citations

• Identification of influenza A nucleoprotein as an antiviral target

  Richard Y Kao;Dan Yang;Lai-Shan Lau;Wayne H W Tsui

  311
  Citations

• Cutting Edge: Novel Function of B Cell-Activating Factor in the Induction of IL-10–Producing Regulatory B Cells

  Min Yang;Lingyun Sun;Shengjun Wang;King-Hung Ko

  278
  Citations

• Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis

  Queenie Lai Kwan Lam;Otis King Hung Ko;Bo-Jian Zheng;Liwei Lu

  265
  Citations

• Identification of a Receptor-Binding Domain in the S Protein of the Novel Human Coronavirus Middle East Respiratory Syndrome Coronavirus as an Essential Target for Vaccine Development

  Lanying Du;Guangyu Zhao;Zhihua Kou;Cuiqing Ma

  264
  Citations

• Complete genome sequence of bat coronavirus HKU2 from Chinese horseshoe bats revealed a much smaller spike gene with a different evolutionary lineage from the rest of the genome

  Susanna K.P. Lau;Patrick C.Y. Woo;Kenneth S.M. Li;Yi Huang

  247
  Citations

• Identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4

  Susanna K. P. Lau;Patrick C. Y. Woo;Herman Tse;Clara T. Y. Fu

  239
  Citations

• Feline morbillivirus, a previously undescribed paramyxovirus associated with tubulointerstitial nephritis in domestic cats

  Patrick C. Y. Woo;Susanna K. P. Lau;Beatrice H. L. Wong;Rachel Y. Y. Fan

  236
  Citations

• Receptor-binding domain of SARS-CoV spike protein induces long-term protective immunity in an animal model.

  Lanying Du;Guangyu Zhao;Yuxian He;Yan Guo

  234
  Citations

• Discovery of a Novel Coronavirus, China Rattus Coronavirus HKU24, from Norway Rats Supports the Murine Origin of Betacoronavirus 1 and Has Implications for the Ancestor of Betacoronavirus Lineage A

  Susanna K.Y. Lau;Patrick C.Y. Woo;Kenneth S.M. Li;Alan K.L. Tsang

  232
  Citations

• Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein.

  Liwei Jiang;Nianshuang Wang;Teng Zuo;Xuanling Shi

  228
  Citations

• Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1

  Stephanie Ma;Kwan Ho Tang;Yuen Piu Chan;Terence K. Lee

  4
  Citations