Lu Lu spends much of his time researching Virology, Coronavirus, Lipid bilayer fusion, Middle East respiratory syndrome coronavirus and Virus. His Virology research is multidisciplinary, relying on both Immunology and Monoclonal antibody. In his research, Coronavirus Infections is intimately related to Pandemic, which falls under the overarching field of Coronavirus.
His work in Lipid bilayer fusion addresses issues such as Viral replication, which are connected to fields such as Plasma protein binding and Gp41. His work on Titer as part of general Virus research is frequently linked to Virulence and Genomic signature, thereby connecting diverse disciplines of science. His study in Viral protein is interdisciplinary in nature, drawing from both Inhibitory postsynaptic potential, Structural biology, Plasma membrane fusion, Protein structure and Peptide.
His primary scientific interests are in Virology, Gp41, Virus, Peptide and Biochemistry. As part of the same scientific family, Lu Lu usually focuses on Virology, concentrating on Antibody and intersecting with Antigen. His Gp41 study combines topics in areas such as Molecular biology, Heptad repeat, Viral envelope and Lipid bilayer fusion.
His research in Peptide intersects with topics in Protein structure, Cell culture, Potency and Fusion inhibitor. Lu Lu has included themes like Sexual transmission and Fusion protein in his Biochemistry study. His work carried out in the field of Coronavirus brings together such families of science as Pandemic and Severe acute respiratory syndrome coronavirus 2.
Lu Lu mainly investigates Virology, Severe acute respiratory syndrome coronavirus 2, Coronavirus, Antibody and Cancer research. His Virology research incorporates elements of Peptide and Antigen. The Coronavirus study which covers Betacoronavirus that intersects with Pandemic.
His work on Epitope, Monoclonal antibody and Neutralizing antibody as part of general Antibody study is frequently linked to Protein domain, therefore connecting diverse disciplines of science. His Cancer research research includes themes of Cancer cell, LNCaP, Receptor and Metastasis. His studies deal with areas such as Cell culture and Enfuvirtide as well as Virus.
His main research concerns Virology, Severe acute respiratory syndrome coronavirus 2, Spike Protein, Lipid bilayer fusion and Coronavirus. The Virology study combines topics in areas such as Cytokine, Immune disorder, Decoy, Proinflammatory cytokine and Lung injury. Lu Lu integrates many fields, such as Spike Protein and engineering, in his works.
His study looks at the intersection of Binding site and topics like Antibody with Peptide library. In general Lipid bilayer fusion study, his work on Plasma membrane fusion often relates to the realm of Protein subunit, thereby connecting several areas of interest. His Coronavirus research focuses on Betacoronavirus and how it relates to Coronavirus Infections.
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Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody.
Xiaolong Tian;Cheng Li;Ailing Huang;Shuai Xia.
Emerging microbes & infections (2020)
Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion.
Shuai Xia;Meiqin Liu;Chao Wang;Wei Xu.
Cell Research (2020)
Neutralizing antibody responses to SARS-CoV-2 in a COVID-19 recovered patient cohort and their implications
Wu F;Wang A;Liu M;Wang Q.
Social Science Research Network (2020)
Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor
Lu Lu;Qi. Liu;Yun Zhu;Kwok-Hung Chan.
Nature Communications (2014)
Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein.
Shuai Xia;Yun Zhu;Meiqin Liu;Qiaoshuai Lan.
Cellular & Molecular Immunology (2020)
SARS-CoV-2 infects T lymphocytes through its spike protein-mediated membrane fusion
Xinling Wang;Wei Xu;Gaowei Hu;Shuai Xia.
Cellular & Molecular Immunology (2020)
Identification of a Receptor-Binding Domain in the S Protein of the Novel Human Coronavirus Middle East Respiratory Syndrome Coronavirus as an Essential Target for Vaccine Development
Lanying Du;Guangyu Zhao;Zhihua Kou;Cuiqing Ma.
Journal of Virology (2013)
Exceptionally Potent Neutralization of Middle East Respiratory Syndrome Coronavirus by Human Monoclonal Antibodies
Tianlei Ying;Lanying Du;Tina W. Ju;Ponraj Prabakaran.
Journal of Virology (2014)
A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike
Shuai Xia;Lei Yan;Wei Xu;Anurodh Shankar Agrawal.
Science Advances (2019)
MERS-CoV spike protein: a key target for antivirals
Lanying Du;Yang Yang;Yusen Zhou;Lu Lu.
Expert Opinion on Therapeutic Targets (2017)
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