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Microbiology

D-Index
54
Citations
10920
World Ranking
3947
National Ranking
1534

Overview

Chien Te K. Tseng is affiliated with The University of Texas Medical Branch at Galveston in the United States. Their research primarily spans the field of Medicine, with a focus on subfields including Infectious Diseases, Molecular Biology, Immunology, Neurology, and Animal Science and Zoology. The majority of their work, totaling 131 publications, centers on these areas.

The scientist's main research topics cover a range of subjects related to viral infections and immunological responses. Key topics include:

  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Viral gastroenteritis research and epidemiology
  • Animal Virus Infections Studies
  • Monoclonal and Polyclonal Antibodies Research
  • Long-Term Effects of COVID-19
  • Computational Drug Discovery Methods

Chien Te K. Tseng's recent papers reflect a strong emphasis on SARS-CoV-2 and COVID-19. Some notable recent publications include:

  • Animal models for COVID-19, 2020, Nature
  • A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19, 2020, Nature Communications
  • A novel receptor-binding domain (RBD)-based mRNA vaccine against SARS-CoV-2, 2020, Cell Research
  • High Potency of a Bivalent Human VH Domain in SARS-CoV-2 Animal Models, 2020, Cell
  • A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors, 2020, ChemMedChem

The scientist collaborates frequently with a consistent group of coauthors. The most frequent coauthors are Aleksandra Drelich, Jason Hsu, Vivian Tat, Bi-Hung Peng, and Pinghan Huang.

In terms of publication venues, Chien Te K. Tseng's work appears frequently in journals and repositories such as bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, Proceedings of the National Academy of Sciences, PLoS ONE, and the Journal of Medicinal Chemistry.

Best Publications

  • Animal models for COVID-19.

    César Muñoz-Fontela;William E. Dowling;Simon G.P. Funnell;Pierre S. Gsell

  • Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus

    Chien Te Tseng;Elena Sbrana;Naoko Iwata-Yoshikawa;Patrick C. Newman

  • Binding of the Hepatitis C Virus Envelope Protein E2 to CD81 Inhibits Natural Killer Cell Functions

    Chien Te K. Tseng;Gary R. Klimpel

  • A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike

    Shuai Xia;Lei Yan;Wei Xu;Anurodh Shankar Agrawal

  • Severe Acute Respiratory Syndrome Coronavirus nsp1 Suppresses Host Gene Expression, Including That of Type I Interferon, in Infected Cells

    Krishna Narayanan;Cheng Huang;Kumari Lokugamage;Wataru Kamitani

  • Regulation of IRF-3-dependent Innate Immunity by the Papain-like Protease Domain of the Severe Acute Respiratory Syndrome Coronavirus *

    Santhana G. Devaraj;Nan Wang;Zhongbin Chen;Zihong Chen

  • Severe Acute Respiratory Syndrome (SARS) Coronavirus-Induced Lung Epithelial Cytokines Exacerbate SARS Pathogenesis by Modulating Intrinsic Functions of Monocyte-Derived Macrophages and Dendritic Cells

    Tomoki Yoshikawa;Terence Hill;Kui Li;Clarence J. Peters

  • Immunization with inactivated Middle East Respiratory Syndrome coronavirus vaccine leads to lung immunopathology on challenge with live virus.

    Anurodh Shankar Agrawal;Xinrong Tao;Abdullah Algaissi;Abdullah Algaissi;Tania Garron

  • Severe Acute Respiratory Syndrome Coronavirus Infection of Mice Transgenic for the Human Angiotensin-Converting Enzyme 2 Virus Receptor

    Chien Te K. Tseng;Cheng Huang;Patrick Newman;Nan Wang

  • Severe acute respiratory syndrome-associated coronavirus vaccines formulated with delta inulin adjuvants provide enhanced protection while ameliorating lung eosinophilic immunopathology.

    Yoshikazu Honda-Okubo;Dale Barnard;Chun Hao Ong;Bi Hung Peng

  • A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19.

    Xuping Xie;Antonio E. Muruato;Xianwen Zhang;Kumari G. Lokugamage

  • A Truncated Receptor-Binding Domain of MERS-CoV Spike Protein Potently Inhibits MERS-CoV Infection and Induces Strong Neutralizing Antibody Responses: Implication for Developing Therapeutics and Vaccines

    Lanying Du;Zhihua Kou;Cuiqing Ma;Xinrong Tao

  • Generation of a Transgenic Mouse Model of Middle East Respiratory Syndrome Coronavirus Infection and Disease

    Anurodh Shankar Agrawal;Tania Garron;Xinrong Tao;Bi Hung Peng

  • Synthesis, crystal structure, structure-activity relationships, and antiviral activity of a potent SARS coronavirus 3CL protease inhibitor.

    Syaulan Yang;Shu Jen Chen;Min Feng Hsu;Jen Dar Wu

  • Severe acute respiratory syndrome and the innate immune responses: Modulation of effector cell function without productive infection

    Chien Te K. Tseng;Lucy A. Perrone;Hongbing Zhu;Shinji Makino

  • Dynamic Innate Immune Responses of Human Bronchial Epithelial Cells to Severe Acute Respiratory Syndrome-Associated Coronavirus Infection

    Tomoki Yoshikawa;Terence E Hill;Naoko Yoshikawa;Vsevolod L Popov

  • Binding of the hepatitis C virus envelope protein E2 to CD81 provides a co‐stimulatory signal for human T cells

    Andreas Wack;Elisabetta Soldaini;Chien Te K. Tseng;Sandra Nuti

  • Apical Entry and Release of Severe Acute Respiratory Syndrome-Associated Coronavirus in Polarized Calu-3 Lung Epithelial Cells

    Chien Te K. Tseng;Jennifer Tseng;Lucy Perrone;Melissa Worthy

  • Intranasal vaccination with recombinant receptor-binding domain of MERS-CoV spike protein induces much stronger local mucosal immune responses than subcutaneous immunization: Implication for designing novel mucosal MERS vaccines

    Cuiqing Ma;Ye Li;Lili Wang;Guangyu Zhao

  • Roadmap to developing a recombinant coronavirus S protein receptor-binding domain vaccine for severe acute respiratory syndrome

    Shibo Jiang;Maria Elena Bottazzi;Lanying Du;Sara Lustigman

Frequent Co-Authors

Shibo Jiang
Shibo Jiang Fudan University
Lanying Du
Lanying Du Georgia State University
Clarence J. Peters
Clarence J. Peters The University of Texas Medical Branch at Galveston
Shinji Makino
Shinji Makino The University of Texas Medical Branch at Galveston
Yusen Zhou
Yusen Zhou Zhengzhou University
Maria Elena Bottazzi
Maria Elena Bottazzi Baylor College of Medicine
Peter J. Hotez
Peter J. Hotez Baylor College of Medicine
Fang Li
Fang Li University of Minnesota
Sara Lustigman
Sara Lustigman New York Blood Center
Dimiter S. Dimitrov
Dimiter S. Dimitrov University of Pittsburgh

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