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55
Citations
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15026
National Ranking
1186

Overview

Sonja Hess is a researcher affiliated with AstraZeneca in the United Kingdom. Their work spans multiple fields primarily within medicine and biochemistry, genetics, and molecular biology. The scientist has contributed notably to the study of complex diseases and molecular mechanisms with a focus on respiratory conditions and genetic factors.

Hess's main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

The subfields in which they have conducted research include:

  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Physiology
  • Genetics
  • Immunology

Key topics addressed in Hess's publications cover:

  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Gut microbiota and health
  • Metabolomics and Mass Spectrometry Studies
  • Genomics and Rare Diseases
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Diabetes Management and Research
  • Clostridium difficile and Clostridium perfringens research

They have authored papers in a range of scientific journals. Frequent publication venues include:

  • Journal of Proteome Research
  • Respiratory Research
  • UNC Libraries
  • JCI Insight
  • Nature

Some of the recent papers by Sonja Hess include:

  • "Rare variant associations with plasma protein levels in the UK Biobank," 2023, Nature
  • "Development of a Parallel Reaction Monitoring Mass Spectrometry Assay for the Detection of SARS-CoV-2 Spike Glycoprotein and Nucleoprotein," 2020, Analytical Chemistry
  • "PD-L1 + neutrophils contribute to injury-induced infection susceptibility," 2021, Science Advances
  • "Engraftment of Bacteria after Fecal Microbiota Transplantation Is Dependent on Both Frequency of Dosing and Duration of Preparative Antibiotic Regimen," 2021, Microorganisms
  • "Genetic architecture of telomere length in 462,666 UK Biobank whole-genome sequences," 2024, Nature Genetics

Sonja Hess has collaborated frequently with a group of co-authors, including:

  • Lisa H. Cazares
  • Daniel Muthas
  • Matthew S. Glover
  • Ventzislava A. Hristova
  • Adam Platt

Best Publications

  • The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3

    Colleen A. McHugh;Chun-Kan Chen;Amy Chow;Christine F. Surka

  • Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy

    Nickie C. Chan;Anna M. Salazar;Anh H Pham;Michael J. Sweredoski

  • The molecular structure of spider dragline silk: Folding and orientation of the protein backbone

    J. D. van Beek;S. Hess;F. Vollrath;B. H. Meier

  • Protein disulfide isomerase acts as an injury response signal that enhances fibrin generation via tissue factor activation

    Christoph Reinhardt;Marie Luise Von Brühl;Davit Manukyan;Lenka Grahl

  • NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism

    Chia-Lin Chen;Dinesh Babu Uthaya Kumar;Vasu Punj;Jun Xu

  • Cand1 Promotes Assembly of New SCF Complexes through Dynamic Exchange of F Box Proteins

    Nathan W. Pierce;J. Eugene Lee;Xing Liu;Michael J. Sweredoski

  • Mycobacterium tuberculosis produces pili during human infection

    Christopher J. Alteri;Juan Xicohténcatl-Cortes;Sonja Hess;Guillermo Caballero-Olín

  • Lignans Isolated from Valerian: Identification and Characterization of a New Olivil Derivative with Partial Agonistic Activity at A1 Adenosine Receptors

    Britta Schumacher;Silke Scholle;Josef Hölzl;Nasser Khudeir

  • Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes

    Jocelyn O. Eidahl;Brandon L. Crowe;Justin A. North;Christopher J. McKee

  • Evaluation and Optimization of Mass Spectrometric Settings during Data-Dependent Acquisition Mode: Focus on LTQ-Orbitrap Mass Analyzers

    Anastasia Kalli;Geoffrey T. Smith;Michael J Sweredoski;Sonja Hess

  • The top-down, middle-down, and bottom-up mass spectrometry approaches for characterization of histone variants and their post-translational modifications

    Annie Moradian;Anastasia Kalli;Michael J. Sweredoski;Sonja Hess

  • A conserved quality-control pathway that mediates degradation of unassembled ribosomal proteins

    Min-Kyung Sung;Tanya R Porras-Yakushi;Justin M Reitsma;Ferdinand M Huber

  • Quantitative proteomic analysis of the secretory proteins from rat adipose cells using a 2D liquid chromatography-MS/MS approach

    Xiaoli Chen;Samuel W. Cushman;Lewis K. Pannell;Sonja Hess

  • Glutamine Triggers Acetylation-Dependent Degradation of Glutamine Synthetase via the Thalidomide Receptor Cereblon

    T. Van Nguyen;J. Eugene Lee;Michael J. Sweredoski;Seung Joo Yang

  • Neamphamide A, a new HIV-inhibitory depsipeptide from the Papua New Guinea marine sponge Neamphius huxleyi.

    Naoya Oku;Kirk R. Gustafson;Laura K. Cartner;Jennifer A. Wilson

  • Interactions of HIV-1 Gag with assembly cofactors.

    Nick Shkriabai;Siddhartha A. K. Datta;Zhuojun Zhao;Sonja Hess

  • Novel Proteomic Tools Reveal Essential Roles of SRP and Importance of Proper Membrane Protein Biogenesis

    Dawei Zhang;Michael J. Sweredoski;Robert L. J. Graham;Sonja Hess

  • Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11

    Jing Li;Tanya Yakushi;Francesco Parlati;Andrew L Mackinnon

  • Composition and Regulation of the Cellular Repertoire of SCF Ubiquitin Ligases

    Justin M. Reitsma;Xing Liu;Kurt M. Reichermeier;Annie Moradian

  • The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3

    Colleen A. McHugh;Chun-Kan Chen;Amy Chow;Christine F. Surka

Frequent Co-Authors

Raymond J. Deshaies
Raymond J. Deshaies California Institute of Technology
Mamuka Kvaratskhelia
Mamuka Kvaratskhelia University of Colorado Denver
Lewis K. Pannell
Lewis K. Pannell National Institutes of Health
Kenneth H. Brown
Kenneth H. Brown University of California, Davis
Erin M. Schuman
Erin M. Schuman Max Planck Society
Dianne K. Newman
Dianne K. Newman California Institute of Technology
David C. Chan
David C. Chan California Institute of Technology
Eric S. Lander
Eric S. Lander Broad Institute

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