World's Best Scientists 2026 revealed!
Frauke Christ

Frauke Christ

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
8047
World Ranking
18070
National Ranking
299

Frauke Christ publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Frauke Christ sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 197 publications — 48th percentile

48% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Frauke Christ D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Frauke Christ sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 49 D-Index — 9th percentile

9% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Frauke Christ is affiliated with KU Leuven in Belgium and has an extensive research portfolio primarily situated in the fields of Biochemistry, Genetics, and Molecular Biology as well as Medicine. Their work spans multiple subfields including Molecular Biology, Virology, Infectious Diseases, Pulmonary and Respiratory Medicine, and Genetics. The primary research topics cover HIV research and treatment, HIV/AIDS drug development and treatment, protein degradation and inhibitors, genetics and neurodevelopmental disorders, cystic fibrosis research advances, ubiquitin and proteasome pathways, and CRISPR and genetic engineering.

Their recent published works include the following papers:

  • "Capsid-Labelled HIV To Investigate the Role of Capsid during Nuclear Import and Integration" (2020) in Journal of Virology
  • "Phenotyping of Rare CFTR Mutations Reveals Distinct Trafficking and Functional Defects" (2020) in Cells
  • "GS-9822, a Preclinical LEDGIN Candidate, Displays a Block-and-Lock Phenotype in Cell Culture" (2021) in Antimicrobial Agents and Chemotherapy
  • "Novel CFTR modulator combinations maximise rescue of G85E and N1303K in rectal organoids" (2022) in ERJ Open Research
  • "Towards a Functional Cure of HIV-1: Insight Into the Chromatin Landscape of the Provirus" (2021) in Frontiers in Microbiology

Frauke Christ has collaborated frequently with a number of researchers including Zeger Debyser, Siska Van Belle, Rik Gijsbers, Marianne Carlon, and M. Ensinck. These collaborations are evidenced by multiple joint publications, with the highest number of co-authored works with Zeger Debyser.

Their research has been disseminated through various publication venues, with multiple articles appearing in bioRxiv (Cold Spring Harbor Laboratory) and the Journal of Cystic Fibrosis. Other notable journals where their work has been featured include Cells, Structure, and Viruses.

Best Publications

  • Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication

    Frauke Christ;Arnout Voet;Arnaud Marchand;Stefan Nicolet;Stefan Nicolet

  • Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication.

    Stéphane Emiliani;Aurélie Mousnier;Katrien Busschots;Marlène Maroun

  • Transportin-SR2 Imports HIV into the Nucleus

    Frauke Christ;Wannes Thys;Jan De Rijck;Rik Gijsbers

  • The Interaction of LEDGF/p75 with Integrase Is Lentivirus-specific and Promotes DNA Binding

    Katrien Busschots;Jo Vercammen;Stéphane Emiliani;Richard Benarous

  • Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus.

    Linos Vandekerckhove;Frauke Christ;Bénédicte Van Maele;Jan De Rijck

  • Cellular co-factors of HIV-1 integration.

    Bénédicte Van Maele;Katrien Busschots;Linos Vandekerckhove;Frauke Christ

  • Overexpression of the Lens Epithelium-Derived Growth Factor/p75 Integrase Binding Domain Inhibits Human Immunodeficiency Virus Replication

    Jan De Rijck;Linos Vandekerckhove;Rik Gijsbers;Anneleen Hombrouck

  • Small-Molecule Inhibitors of the LEDGF/p75 Binding Site of Integrase Block HIV Replication and Modulate Integrase Multimerization

    Frauke Christ;Stephen Shaw;Jonas Demeulemeester;Belete Ayele Desimmie

  • Investigations on the 4-quinolone-3-carboxylic acid motif. 1. Synthesis and structure-activity relationship of a class of human immunodeficiency virus type 1 integrase inhibitors.

    Serena Pasquini;Claudia Mugnaini;Cristina Tintori;Maurizio Botta

  • Identification of the LEDGF/p75 Binding Site in HIV-1 Integrase

    Katrien Busschots;Arnout Voet;Marc De Maeyer;Jean-Christophe Rain

  • Magnesium Chelating 2-Hydroxyisoquinoline-1,3(2H,4H)-diones, as Inhibitors of HIV-1 Integrase and/or the HIV-1 Reverse Transcriptase Ribonuclease H Domain: Discovery of a Novel Selective Inhibitor of the Ribonuclease H Function

    Muriel Billamboz;Fabrice Bailly;Cédric Lion;Nadia Touati;Nadia Touati

  • Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV.

    Anneleen Hombrouck;Jan De Rijck;Jelle Hendrix;Linos Vandekerckhove

  • LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions

    Belete Ayele Desimmie;Rik Schrijvers;Jonas Demeulemeester;Doortje Borrenberghs

  • Design, synthesis, and biological evaluation of a series of 2-hydroxyisoquinoline-1,3(2H,4H)-diones as dual inhibitors of human immunodeficiency virus type 1 integrase and the reverse transcriptase RNase H domain

    Muriel Billamboz;Fabrice Bailly;Maria Letizia Barreca;Laura De Luca

  • LEDGF/p75-Independent HIV-1 Replication Demonstrates a Role for HRP-2 and Remains Sensitive to Inhibition by LEDGINs

    Rik Schrijvers;Jan De Rijck;Jonas Demeulemeester;Noritaka Adachi

  • Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity.

    Teshome L. Aboye;Helen Ha;Subhabrata Majumder;Frauke Christ

  • Pharmacophore-Based Discovery of Small-Molecule Inhibitors of Protein–Protein Interactions between HIV-1 Integrase and Cellular Cofactor LEDGF/p75

    Laura De Luca;Maria Letizia Barreca;Stefania Ferro;Frauke Christ

  • The LEDGF/p75 integrase interaction, a novel target for anti-HIV therapy.

    Frauke Christ;Zeger Debyser

  • Lens Epithelium-derived Growth Factor/p75 Interacts with the Transposase-derived DDE Domain of PogZ

    Koen Bartholomeeusen;Frauke Christ;Jelle Hendrix;Jean-Christophe Rain

  • Differential interaction of HIV-1 integrase and JPO2 with the C terminus of LEDGF/p75.

    Koen Bartholomeeusen;Jan De Rijck;Katrien Busschots;Linda Desender

Frequent Co-Authors

Zeger Debyser
Zeger Debyser KU Leuven
Rik Gijsbers
Rik Gijsbers KU Leuven
Alba Chimirri
Alba Chimirri University of Messina
Maurizio Botta
Maurizio Botta University of Siena
Nouri Neamati
Nouri Neamati University of Michigan–Ann Arbor
Alfred Pingoud
Alfred Pingoud University of Giessen
Frederic D. Bushman
Frederic D. Bushman University of Pennsylvania

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