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Molecular Biology

D-Index
51
Citations
12161
World Ranking
2488
National Ranking
1229

Overview

Jian-Hua Luo is affiliated with the University of Pittsburgh in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a strong focus on molecular and cancer-related studies. Luo's work covers a range of important topics in cancer genomics, gene regulation, immune cell involvement in cancer, and RNA modifications related to cancer progression.

The main fields of study for Jian-Hua Luo include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, they have contributed notably to several subfields, such as:

  • Molecular Biology
  • Cancer Research
  • Immunology
  • Oncology
  • Pulmonary and Respiratory Medicine

Luo's research topics emphasize:

  • RNA modifications and cancer
  • Cancer Genomics and Diagnostics
  • Cancer-related gene regulation
  • Immune cells in cancer
  • Prostate Cancer Treatment and Research
  • Cancer-related molecular mechanisms research
  • Cancer Immunotherapy and Biomarkers

Among their recent publications are:

  • "The DNA methylation landscape of advanced prostate cancer" (2020), published in Nature Genetics
  • "NOTCH-YAP1/TEAD-DNMT1 Axis Drives Hepatocyte Reprogramming Into Intrahepatic Cholangiocarcinoma" (2022), published in Gastroenterology
  • "Genome-wide transcriptomic analysis of microglia reveals impaired responses in aged mice after cerebral ischemia" (2020), published in Journal of Cerebral Blood Flow & Metabolism
  • "CTCF loss mediates unique DNA hypermethylation landscapes in human cancers" (2020), published in Clinical Epigenetics
  • "Transcriptomic and functional studies reveal undermined chemotactic and angiostimulatory properties of aged microglia during stroke recovery" (2020), published in Journal of Cerebral Blood Flow & Metabolism

Jian-Hua Luo frequently publishes in venues including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • American Journal Of Pathology
  • The FASEB Journal
  • Hepatology Communications

Luo has collaborated extensively with researchers such as:

  • Silvia Liu
  • Yanping Yu
  • Bao-Guo Ren
  • Junyan Tao
  • George K. Michalopoulos

Best Publications

  • The Molecular Taxonomy of Primary Prostate Cancer

    Adam Abeshouse;Jaeil Ahn;Rehan Akbani;Adrian Ally

  • Gene Expression Alterations in Prostate Cancer Predicting Tumor Aggression and Preceding Development of Malignancy

    Yan Ping Yu;Douglas Landsittel;Ling Jing;Joel Nelson

  • C2 Region-derived Peptides Inhibit Translocation and Function of β Protein Kinase C in Vivo

    Dorit Ron;Jianhua Luo;Daria Mochly-Rosen

  • Transcriptomic and genomic analysis of human hepatocellular carcinomas and hepatoblastomas

    Jian-Hua Luo;Baoguo Ren;Sergei Keryanov;George C. Tseng

  • Overexpression of Dicer in precursor lesions of lung adenocarcinoma.

    Simion Chiosea;Elena Jelezcova;Uma Chandran;Jianhua Luo

  • Gene expression analysis of prostate cancers

    Jian-Hua Luo;Yan Ping Yu;Kathleen Cieply;Fan Lin

  • Identification of the transforming STRN-ALK fusion as a potential therapeutic target in the aggressive forms of thyroid cancer

    Lindsey M. Kelly;Guillermo Barila;Pengyuan Liu;Viktoria N. Evdokimova

  • Epidermal Growth Factor Receptor: A Novel Target of the Wnt/β-Catenin Pathway in Liver

    Xinping Tan;Udayan Apte;Amanda Micsenyi;Emorphia Kotsagrelos

  • The DNA methylation landscape of advanced prostate cancer

    Shuang G. Zhao;Shuang G. Zhao;William S. Chen;William S. Chen;Haolong Li;Adam Foye

  • Glutathione Peroxidase 3, Deleted or Methylated in Prostate Cancer, Suppresses Prostate Cancer Growth and Metastasis

    Yan P. Yu;Guoying Yu;George Tseng;Kathleen Cieply

  • MCM7 amplification and overexpression are associated with prostate cancer progression.

    Ren B;Yu G;Tseng Gc;Cieply K

  • β-Catenin is temporally regulated during normal liver development

    Amanda Micsenyi;Xinping Tan;Tamara Sneddon;Jian-Hua Luo

  • Enhanced liver regeneration following changes induced by hepatocyte-specific genetic ablation of integrin-linked kinase

    Udayan Apte;Vasiliki Gkretsi;William C. Bowen;Wendy M. Mars

  • HGF-, EGF-, and dexamethasone-induced gene expression patterns during formation of tissue in hepatic organoid cultures.

    George K. Michalopoulos;William C. Bowen;Karen Mulé;Jianhua Luo

  • Calpain-2 as a Target for Limiting Prostate Cancer Invasion

    Asmaa Mamoune;Jian-Hua Luo;Douglas A Lauffenburger;Alan Wells

  • Calcium-dependent activation of protein kinase C. The role of the C2 domain in divalent cation selectivity

    J H Luo;I B Weinstein

  • Targeting genomic rearrangements in tumor cells through Cas9-mediated insertion of a suicide gene

    Zhang-Hui Chen;Yan P Yu;Ze-Hua Zuo;Joel B Nelson

  • Mechanisms of Hepatocyte Growth Factor-Mediated and Epidermal Growth Factor-Mediated Signaling in Transdifferentiation of Rat Hepatocytes to Biliary Epithelium

    Pallavi B. Limaye;William C. Bowen;Anne V. Orr;Jianhua Luo

  • Cell cycle effects resulting from inhibition of hepatocyte growth factor and its receptor c-Met in regenerating rat livers by RNA interference

    Shirish Paranjpe;William C. Bowen;Aaron W. Bell;Kari Nejak-Bowen

  • The Molecular Taxonomy of Primary Prostate Cancer

    Adam Abeshouse;Jaeil Ahn;Rehan Akbani;Adrian Ally

Frequent Co-Authors

George K. Michalopoulos
George K. Michalopoulos University of Pittsburgh
Satdarshan P. Monga
Satdarshan P. Monga University of Pittsburgh
Rajiv Dhir
Rajiv Dhir University of Pittsburgh
Michael A. Nalesnik
Michael A. Nalesnik University of Pittsburgh
Alan Wells
Alan Wells University of Pittsburgh
Harry C. Blair
Harry C. Blair University of Pittsburgh
Paul C. Boutros
Paul C. Boutros University of California, Los Angeles
Laure Aurelian
Laure Aurelian University of Maryland, Baltimore
Chuanyue Wu
Chuanyue Wu University of Pittsburgh
Xiaoming Hu
Xiaoming Hu University of Pittsburgh

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