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Neuroscience

D-Index
71
Citations
17718
World Ranking
2414
National Ranking
1140

Overview

Xiaoming Hu is affiliated with the University of Pittsburgh in the United States and conducts research primarily in the fields of Medicine and Neuroscience. Their work has substantial focus on Neurology, Immunology, and Molecular Biology, with additional contributions related to Epidemiology and Pulmonary and Respiratory Medicine.

The scientist's research concentrates on key topics including Neuroinflammation and Neurodegeneration Mechanisms, Immune cells in cancer, Neurological Disease Mechanisms and Treatments, Immune Response and Inflammation, Diabetic Foot Ulcer Assessment and Management, Parkinson's Disease Mechanisms and Treatments, and Nerve injury and regeneration.

Selected recent papers by Xiaoming Hu include:

  • Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke (2021, Immunity)
  • Phagocytic microglia and macrophages in brain injury and repair (2022, CNS Neuroscience & Therapeutics)
  • IL-4/STAT6 signaling facilitates innate hematoma resolution and neurological recovery after hemorrhagic stroke in mice (2020, Proceedings of the National Academy of Sciences)
  • Microglial/Macrophage polarization and function in brain injury and repair after stroke (2021, CNS Neuroscience & Therapeutics)
  • Transforming Growth Factor Beta-Activated Kinase 1-Dependent Microglial and Macrophage Responses Aggravate Long-Term Outcomes After Ischemic Stroke (2020, Stroke)

Frequent co-authors associated with Xiaoming Hu are:

  • Rehana K. Leak
  • Jun Chen
  • Yejie Shi
  • Fei Xu
  • R. Anne Stetler

Regarding publication venues, Xiaoming Hu has contributed notably to:

  • Journal of Cerebral Blood Flow & Metabolism
  • Stroke
  • Neurobiology of Disease
  • CNS Neuroscience & Therapeutics
  • Proceedings of the National Academy of Sciences

Best Publications

  • Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

    Xiaoming Hu;Peiying Li;Yanling Guo;Haiying Wang

  • Microglial and Macrophage polarization—new Prospects for Brain Repair

    Xiaoming Hu;Rehana K. Leak;Yejie Shi;Jun Suenaga

  • Microglia/macrophage polarization dynamics in white matter after traumatic brain injury

    Guohua Wang;Jia Zhang;Xiaoming Hu;Xiaoming Hu;Lili Zhang;Lili Zhang

  • Cerebral Vascular Disease and Neurovascular Injury in Ischemic Stroke

    Xiaoming Hu;T. Michael De Silva;Jun Chen;Frank M. Faraci

  • Interleukin-4 Is Essential for Microglia/Macrophage M2 Polarization and Long-Term Recovery After Cerebral Ischemia

    Xiangrong Liu;Jia Liu;Shangfeng Zhao;Haiyue Zhang

  • Rapid endothelial cytoskeletal reorganization enables early blood-brain barrier disruption and long-term ischaemic reperfusion brain injury.

    Yejie Shi;Yejie Shi;Lili Zhang;Lili Zhang;Lili Zhang;Hongjian Pu;Hongjian Pu;Leilei Mao;Leilei Mao

  • HDAC inhibition prevents white matter injury by modulating microglia/macrophage polarization through the GSK3β/PTEN/Akt axis

    Guohua Wang;Yejie Shi;Xiaoyan Jiang;Rehana K. Leak

  • Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke

    Ligen Shi;Zeyu Sun;Wei Su;Fei Xu;Fei Xu

  • Astrogliosis in CNS pathologies: is there a role for microglia?

    Dan Zhang;Xiaoming Hu;Xiaoming Hu;Li Qian;Li Qian;James P. O’Callaghan

  • Adoptive regulatory T cell therapy protects against cerebral ischemia

    Peiying Li;Yu Gan;Bao-Liang Sun;Feng Zhang;Feng Zhang

  • STAT6/Arg1 promotes microglia/macrophage efferocytosis and inflammation resolution in stroke mice

    Wei Cai;Xuejiao Dai;Jie Chen;Jie Chen;Jingyan Zhao

  • Dysfunction of the neurovascular unit in ischemic stroke and neurodegenerative diseases: An aging effect

    Wei Cai;Kai Zhang;Peiying Li;Ling Zhu

  • Aging of cerebral white matter.

    Huan Liu;Yuanyuan Yang;Yuguo Xia;Wen Zhu

  • Enhanced Oligodendrogenesis and Recovery of Neurological Function by Erythropoietin After Neonatal Hypoxic/Ischemic Brain Injury

    Masanori Iwai;R. Anne Stetler;Juan Xing;Xiaoming Hu

  • Peroxisome proliferator-activated receptor γ (PPARγ): A master gatekeeper in CNS injury and repair.

    Wei Cai;Tuo Yang;Huan Liu;Lijuan Han

  • Preconditioning Provides Neuroprotection in Models of CNS Disease: Paradigms and Clinical Significance

    R. Anne Stetler;Rehana K. Leak;Yu Gan;Peiying Li

  • Molecular dialogs between the ischemic brain and the peripheral immune system: Dualistic roles in injury and repair

    Chengrui An;Yejie Shi;Peiying Li;Xiaoming Hu;Xiaoming Hu;Xiaoming Hu

  • Functional Role of Regulatory Lymphocytes in Stroke Facts and Controversies

    Arthur Liesz;Xiaoming Hu;Christoph Kleinschnitz;Halina Offner

  • Novel neuroprotective mechanisms of memantine: increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation.

    Hung Ming Wu;Nian Sheng Tzeng;Nian Sheng Tzeng;Li Qian;Li Qian;Sung Jen Wei;Sung Jen Wei

  • Omega-3 Fatty Acids Protect the Brain against Ischemic Injury by Activating Nrf2 and Upregulating Heme Oxygenase 1

    Meijuan Zhang;Suping Wang;Leilei Mao;Leilei Mao;Rehana K. Leak

  • ST2/IL-33-Dependent Microglial Response Limits Acute Ischemic Brain Injury

    Yuanyuan Yang;Huan Liu;Haiyue Zhang;Qing Ye

  • White matter injury and microglia/macrophage polarization are strongly linked with age-related long-term deficits in neurological function after stroke

    Jun Suenaga;Xiaoming Hu;Hongjian Pu;Yejie Shi

  • Peroxiredoxin-2 Protects against 6-Hydroxydopamine-Induced Dopaminergic Neurodegeneration via Attenuation of the Apoptosis Signal-Regulating Kinase (ASK1) Signaling Cascade

    X. Hu;Z. Weng;C. T. Chu;L. Zhang

  • Neurotransmitter receptors on microglia

    Huan Liu;Rehana K Leak;Xiaoming Hu

Frequent Co-Authors

Michael V. L. Bennett
Michael V. L. Bennett Albert Einstein College of Medicine
C. Edward Dixon
C. Edward Dixon University of Pittsburgh
Jia Guo
Jia Guo Fudan University
Ling Chen
Ling Chen Nanjing University
Dandan Sun
Dandan Sun University of Pittsburgh
Gregg E. Homanics
Gregg E. Homanics University of Pittsburgh
Po See Chen
Po See Chen National Cheng Kung University
Teresa G. Hastings
Teresa G. Hastings University of Pittsburgh
Donna B. Stolz
Donna B. Stolz University of Pittsburgh
James P. O'Callaghan
James P. O'Callaghan National Institute for Occupational Safety and Health

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