World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
22302
World Ranking
18528
National Ranking
7563

Overview

Michelle L. Block is a researcher affiliated with Indiana University - Purdue University Indianapolis in the United States. Their work primarily focuses on the intersections of medicine with subfields including neurology, health, toxicology and mutagenesis, immunology, clinical biochemistry, and speech and hearing.

The scientist's research topics cover a range of subjects related to neuroinflammation and neurodegeneration mechanisms, air quality and its health impacts, advanced glycation end products research, noise effects and management, inflammation biomarkers and pathways, apelin-related biomedical research, and fibromyalgia and chronic fatigue syndrome research.

Michelle L. Block has contributed to multiple recent research papers, including the following:

  • The bidirectional lung brain-axis of amyloid-β pathology: ozone dysregulates the peri-plaque microenvironment, 2022, Brain
  • Diesel exhaust impairs TREM2 to dysregulate neuroinflammation, 2020, Journal of Neuroinflammation
  • Circulating HMGB1 is elevated in veterans with Gulf War Illness and triggers the persistent pro-inflammatory microglia phenotype in male C57Bl/6J mice, 2021, Translational Psychiatry
  • A common language for Gulf War Illness (GWI) research studies: GWI common data elements, 2021, Life Sciences
  • Peripheral HMGB1 is linked to O3 pathology of disease-associated astrocytes and amyloid, 2024, Alzheimer's & Dementia

The frequent co-authors collaborating with Michelle L. Block include Hendrik J. Greve, Carla Garza-Lombó, Chandrama Ahmed, Christen L. Mumaw, and James Johnson.

Their publications have appeared in venues such as UNC Libraries, Brain, Journal of Neuroinflammation, Life Sciences, and Alzheimer's & Dementia, demonstrating engagement with both specialized journals and broader academic repositories.

Best Publications

  • Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

    Michelle L. Block;Luigi Zecca;Jau Shyong Hong

  • Systemic LPS Causes Chronic Neuroinflammation and Progressive Neurodegeneration

    Liya Qin;Xuefei Wu;Michelle L. Block;Yuxin Liu;Yuxin Liu

  • Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism

    Michelle L. Block;Jau Shyong Hong

  • Aggregated α-synuclein activates microglia: a process leading to disease progression in Parkinson’s disease

    Wei Zhang;Tongguang Wang;Zhong Pei;David S. Miller

  • Air pollution: mechanisms of neuroinflammation and CNS disease

    Michelle L. Block;Lilian Calderón-Garcidueñas

  • Microglial activation and chronic neurodegeneration

    Melinda E. Lull;Michelle L. Block

  • NADPH Oxidase Mediates Lipopolysaccharide-induced Neurotoxicity and Proinflammatory Gene Expression in Activated Microglia

    Liya Qin;Yuxin Liu;Tongguang Wang;Sung Jen Wei

  • The Outdoor Air Pollution and Brain Health Workshop

    Michelle L. Block;Alison Elder;Richard L. Auten;Staci D. Bilbo

  • Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: the role of microglia, phagocytosis, and NADPH oxidase

    M. L. Block;X. Wu;X. Wu;Z. Pei;G. Li

  • Chronic microglial activation and progressive dopaminergic neurotoxicity

    M.L. Block;M.L. Block;J.-S. Hong

  • Diesel Exhaust Activates and Primes Microglia: Air Pollution, Neuroinflammation, and Regulation of Dopaminergic Neurotoxicity

    Shannon Levesque;Thomas Taetzsch;Melinda E. Lull;Urmila Kodavanti

  • Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons

    Xuefei Wu;Po See Chen;Po See Chen;Shannon Dallas;Belinda Wilson

  • Air pollution & the brain: Subchronic diesel exhaust exposure causes neuroinflammation and elevates early markers of neurodegenerative disease

    Shannon Levesque;Michael J Surace;Jacob McDonald;Michelle L Block

  • Neuroinflammation, Hyperphosphorylated Tau, Diffuse Amyloid Plaques, and Down-Regulation of the Cellular Prion Protein in Air Pollution Exposed Children and Young Adults

    Lilian Calderón-Garcidueas;Michael Kavanaugh;Michelle Block;Amedeo D'Angiulli

  • Retinoic Acid Attenuates β-Amyloid Deposition and Rescues Memory Deficits in an Alzheimer's Disease Transgenic Mouse Model

    Yun Ding;Aimin Qiao;Ziqing Wang;J. Shawn Goodwin

  • Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier

    Anika M.S. Hartz;Björn Bauer;Michelle L. Block;Jau Shyong Hong

  • Interactive role of the toll-like receptor 4 and reactive oxygen species in LPS-induced microglia activation.

    Liya Qin;Guorong Li;Xun Qian;Yuxin Liu

  • A pivotal role of matrix metalloproteinase-3 activity in dopaminergic neuronal degeneration via microglial activation

    Yoon Seong Kim;Dong Hee Choi;Michelle L. Block;Stefan Lorenzl

  • NADPH oxidase as a therapeutic target in Alzheimer's disease

    Michelle L Block

  • Particulate matter, oxidative stress and neurotoxicity.

    Sheba M.J. MohanKumar;Arezoo Campbell;Michelle Block;Bellina Veronesi

Frequent Co-Authors

Jau-Shyong Hong
Jau-Shyong Hong National Institutes of Health
Belinda Wilson
Belinda Wilson National Institutes of Health
Urmila P. Kodavanti
Urmila P. Kodavanti Environmental Protection Agency
Po See Chen
Po See Chen National Cheng Kung University
Matthew J. Campen
Matthew J. Campen University of New Mexico
Daniele Piomelli
Daniele Piomelli University of California, Irvine
Richard D. Minshall
Richard D. Minshall University of Illinois at Chicago
Luigi Zecca
Luigi Zecca National Academies of Sciences, Engineering, and Medicine
Chris D. Frith
Chris D. Frith University College London
Beate Ritz
Beate Ritz University of California, Los Angeles

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Biology or Biochemistry in the USA opens the door to many specialized online degrees and career pathways. For those interested in nutrition and wellness careers, there are excellent registered dietitian masters programs available online, offering advanced expertise and industry credentials.

If you are looking for entry-level positions in healthcare, consider exploring financial aid for medical assistant programs, which can make quality education more accessible and affordable.

For medical assistants aiming to advance, specialized ma to lpn bridge programs online provide a flexible route to become a Licensed Practical Nurse and boost career prospects.

Ambitious students can also consider an accelerated biology degree online, allowing them to complete their studies faster and enter the workforce or graduate programs sooner.

Whether your goal is research, healthcare, or advanced study, these paths can help you build skills, improve qualifications, and achieve your professional ambitions in the dynamic fields of Biology and Biochemistry.

Best Scientists Citing Michelle L. Block

Trending Scientists