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D-Index
91
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30738
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11742
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Overview

Fulton T. Crews is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily focuses on neuroscience, with a significant emphasis on neuroinflammation and neurodegeneration mechanisms.

The scientist has contributed extensively to the field of neuroscience, with research spanning subfields such as neurology, cellular and molecular neuroscience, developmental neuroscience, physiology, and molecular biology. Their work addresses critical topics including neuroinflammation and neurodegeneration mechanisms, neurogenesis and neuroplasticity mechanisms, tryptophan and brain disorders, neuroscience and neuropharmacology research, adipose tissue and metabolism, stress responses and cortisol, and fatty acid research and health.

Fulton T. Crews has published a substantial number of papers, often appearing in prominent venues. Frequent publication venues include UNC Libraries, bioRxiv (Cold Spring Harbor Laboratory), Alcohol, Frontiers in Pharmacology, and Journal of Neuroinflammation.

Notable recent papers authored or co-authored by Crews include:

  • Neuroimmune Function and the Consequences of Alcohol Exposure (2020, UNC Libraries)
  • Microglial depletion and repopulation in brain slice culture normalizes sensitized proinflammatory signaling (2020, Journal of Neuroinflammation)
  • Increased Toll-like Receptor-MyD88-NFκB-Proinflammatory neuroimmune signaling in the orbitofrontal cortex of humans with alcohol use disorder (2021, Alcoholism Clinical and Experimental Research)
  • Extracellular microvesicles promote microglia-mediated pro-inflammatory responses to ethanol (2021, Journal of Neuroscience Research)
  • TRAIL Mediates Neuronal Death in AUD: A Link between Neuroinflammation and Neurodegeneration (2021, International Journal of Molecular Sciences)

The scientist frequently collaborates with several other researchers, including:

  • Ryan P. Vetreno
  • Leon G. Coleman
  • Liya Qin
  • Victoria A. Macht
  • Donita L. Robinson

Fulton T. Crews's body of work has helped to explore in depth the mechanisms linking neuroimmune responses with alcohol exposure and related disorders. This includes research on microglial activity, proinflammatory signaling pathways, and the neurodegenerative consequences associated with alcohol use.

Best Publications

  • Systemic LPS Causes Chronic Neuroinflammation and Progressive Neurodegeneration

    Liya Qin;Xuefei Wu;Michelle L. Block;Yuxin Liu;Yuxin Liu

  • Adolescent cortical development : A critical period of vulnerability for addiction

    Fulton Crews;Jun He;Clyde Hodge

  • Impulsivity, frontal lobes and risk for addiction

    Fulton Timm Crews;Charlotte Ann Boettiger

  • Mechanisms of Neurodegeneration and Regeneration in Alcoholism

    Fulton T. Crews;Kim Nixon

  • Pharmacological treatment of alcohol dependence - A review of the evidence

    James C. Garbutt;Suzanne L. West;Timothy S. Carey;Kathleen N. Lohr

  • Binge ethanol consumption causes differential brain damage in young adolescent rats compared with adult rats.

    Fulton T. Crews;Christopher J. Braun;Blair Hoplight;Robert C. Switzer

  • Binge ethanol exposure decreases neurogenesis in adult rat hippocampus

    Kimberly Nixon;Fulton T. Crews

  • Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment

    Liya Qin;Jun He;Richard N. Hanes;Olivera Pluzarev

  • Increased MCP-1 and microglia in various regions of the human alcoholic brain.

    Jun He;Fulton T. Crews

  • Cytokines and Alcohol

    Fulton T. Crews;Rabih Bechara;Lou Ann Brown;David M. Guidot

  • TNFα potentiates glutamate neurotoxicity by inhibiting glutamate uptake in organotypic brain slice cultures: neuroprotection by NFκB inhibition

    Jian Y. Zou;Fulton T. Crews

  • Presynaptic alpha-receptor subsensitivity after long-term antidepressant treatment

    Fulton T. Crews;Charles B. Smith

  • Effects of ethanol on ion channels.

    F T Crews;A L Morrow;H Criswell;G Breese

  • Induction of innate immune genes in brain create the neurobiology of addiction.

    F.T. Crews;Jian Zou;Liya Qin

  • NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration

    Liya Qin;Fulton T Crews

  • Neurogenesis in adolescent brain is potently inhibited by ethanol

    F.T. Crews;A. Mdzinarishvili;D. Kim;J. He

  • Cognitive deficits and CNS damage after a 4-day binge ethanol exposure in rats

    Jennifer A. Obernier;Aaron M. White;H.Scott Swartzwelder;H.Scott Swartzwelder;Fulton T. Crews

  • The role of neuroimmune signaling in alcoholism.

    Fulton T. Crews;Colleen J. Lawrimore;T. Jordan Walter;Leon G. Coleman

  • NADPH oxidase and aging drive microglial activation, oxidative stress and dopaminergic neurodegeneration following systemic LPS administration

    Liya Qin;Yuxin Liu;Jau Shyong Hong;Fulton T. Crews

  • Adolescent Alcohol Exposure Persistently Impacts Adult Neurobiology and Behavior

    Fulton T. Crews;Ryan P. Vetreno;Margaret A. Broadwater;Donita L. Robinson

Frequent Co-Authors

Rueben A. Gonzales
Rueben A. Gonzales The University of Texas at Austin
Wen Liu
Wen Liu Peking University
Mohan K. Raizada
Mohan K. Raizada University of Florida
L. Judson Chandler
L. Judson Chandler Medical University of South Carolina
Colin Sumners
Colin Sumners University of Florida
Kimberly Nixon
Kimberly Nixon The University of Texas at Austin
Fusao Hirata
Fusao Hirata Johns Hopkins University
Cindy L. Ehlers
Cindy L. Ehlers Scripps Research Institute
Julius Axelrod
Julius Axelrod National Institutes of Health
Reuben P. Siraganian
Reuben P. Siraganian National Institutes of Health

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