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D-Index & Metrics

Medicine

D-Index
80
Citations
18292
World Ranking
17309
National Ranking
8674

Overview

David H. Overstreet was affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily focused on neuroscience and medicine, with significant contributions to subfields including behavioral neuroscience, cellular and molecular neuroscience, biological psychiatry, physiology, and pediatrics, perinatology, and child health.

Their work centered on topics related to stress responses and cortisol, tryptophan and brain disorders, neurotransmitter receptor influence on behavior, eicosanoids and hypertension pharmacology, neuroendocrine regulation and behavior, adipose tissue and metabolism, as well as birth, development, and health.

Frequent collaborators included George R. Breese, Darin J. Knapp, Tiffany A. Wills, Montserrat Navarro, and Robert A. Angel.

The scientist published predominantly in the venue UNC Libraries, where they contributed to 27 publications. Notable recent papers included:

  • Gestational ethanol and nicotine exposure: Effects on maternal behavior, oxytocin, and offspring ethanol intake in the rat (2020, UNC Libraries)
  • Fear induced neuronal alterations in a genetic model of depression: An fMRI study on awake animals (2020, UNC Libraries)
  • Prior Multiple Ethanol Withdrawals Enhance Stress-Induced Anxiety-Like Behavior: Inhibition by CRF1- and Benzodiazepine-Receptor Antagonists and a 5-HT1a-Receptor Agonist (2020, UNC Libraries)
  • Increased stress-evoked nitric oxide signalling in the Flinders sensitive line (FSL) rat: a genetic animal model of depression (2021, UNC Libraries)
  • Repeated Lipopolysaccharide (LPS) or Cytokine Treatments Sensitize Ethanol Withdrawal-Induced Anxiety-Like Behavior (2020, UNC Libraries)

Best Publications

  • The Flinders sensitive line rats: a genetic animal model of depression.

    David H. Overstreet

  • The Flinders Sensitive Line rat: a selectively bred putative animal model of depression.

    David H. Overstreet;Elliot Friedman;Aleksander A. Mathé;Gal Yadid

  • Alterations in neuropeptide Y levels and Y1 binding sites in the Flinders Sensitive Line rats, a genetic animal model of depression.

    Laura Caberlotto;Patricia Jimenez;David H. Overstreet;Yasmin L. Hurd

  • Stress enhancement of craving during sobriety: a risk for relapse.

    George R. Breese;Kathleen Chu;Christopher V. Dayas;Douglas Funk

  • Chronic mild stress-induced anhedonia: greater effect in a genetic rat model of depression.

    Olgierd Pucilowski;David H Overstreet;Amir H Rezvani;David S Janowsky

  • Modeling depression in animal models

    David H. Overstreet

  • Antidepressant effects of nicotine in an animal model of depression.

    Y. Tizabi;David H. Overstreet;Amir H. Rezvani;Vely A. Louis

  • The Flinders Sensitive Line Rat Model of Depression—25 Years and Still Producing

    David H. Overstreet;Gregers Wegener

  • Saccharin intake predicts ethanol intake in genetically heterogeneous rats as well as different rat strains.

    David H. Overstreet;Alexey B. Kampov-Polevoy;Amir H. Rezvani;Lenn Murrelle

  • Effects of chronic mild stress on serum complement activity, saccharin preference, and corticosterone levels in Flinders lines of rats.

    Wellington K. Ayensu;Olgierd Pucilowski;George A. Mason;David H. Overstreet

  • Modulation of multiple ethanol withdrawal-induced anxiety-like behavior by CRF and CRF1 receptors.

    David H. Overstreet;Darin J. Knapp;George R. Breese

  • Accentuated decrease in social interaction in rats subjected to repeated ethanol withdrawals.

    David H. Overstreet;Darin J. Knapp;George R. Breese

  • Conceptual framework for the etiology of alcoholism: a "kindling"/stress hypothesis.

    George R. Breese;David H. Overstreet;Darin J. Knapp

  • Association between depressive behavior and absence of serotonin–dopamine interaction in the nucleus accumbens

    Abraham Zangen;Rachel Nakash;David H. Overstreet;Gal Yadid

  • Administration of antidepressants, diazepam and psychomotor stimulants further confirms the utility of Flinders Sensitive Line rats as an animal model of depression

    D H Overstreet;O Pucilowski;A H Rezvani;D S Janowsky

  • High Serotonin and 5‐Hydroxyindoleacetic Acid Levels in Limbic Brain Regions in a Rat Model of Depression; Normalization by Chronic Antidepressant Treatment

    Abraham Zangen;David H. Overstreet;Gal Yadid

  • Is cholinergic sensitivity a genetic marker for the affective disorders

    David S. Janowsky;David H. Overstreet;John I. Nurnberger

  • Genetic Animal Models of Depression and Ethanol Preference Provide Support for Cholinergic and Serotonergic Involvement in Depression and Alcoholism

    David H. Overstreet;Amir H. Rezvani;David S. Janowsky

  • Attenuation of alcohol intake by Ibogaine in three strains of alcohol-preferring rats

    A. H. Rezvani;D. H. Overstreet;Yue-Wei Lee

  • MK-801 potently inhibits alcohol withdrawal seizures in rats

    Richard A. Morrisett;Richard A. Morrisett;Amir H. Rezvani;David Overstreet;David S. Janowsky

Frequent Co-Authors

Amir H. Rezvani
Amir H. Rezvani Duke University
David S. Janowsky
David S. Janowsky University of California, San Diego
George R. Breese
George R. Breese University of North Carolina at Chapel Hill
Gal Yadid
Gal Yadid Bar-Ilan University
Abraham Zangen
Abraham Zangen Ben-Gurion University of the Negev
Aleksander A. Mathé
Aleksander A. Mathé Karolinska Institute
Aron Weller
Aron Weller Bar-Ilan University
Meir Steiner
Meir Steiner McMaster University
Yasmin L. Hurd
Yasmin L. Hurd Icahn School of Medicine at Mount Sinai
Andrew J. Lawrence
Andrew J. Lawrence Florey Institute of Neuroscience and Mental Health

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