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Medicine

D-Index
99
Citations
34890
World Ranking
8619
National Ranking
4445

Overview

George R. Breese is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily focuses on neuroscience, with a significant body of work spanning cellular and molecular neuroscience, physiology, behavioral neuroscience, molecular biology, and biological psychiatry.

Their scientific contributions cover various topics including:

  • Stress Responses and Cortisol
  • Adipose Tissue and Metabolism
  • Tryptophan and Brain Disorders
  • Eicosanoids and Hypertension Pharmacology
  • Neuroscience and Neuropharmacology Research
  • Neurotransmitter Receptor Influence on Behavior
  • Receptor Mechanisms and Signaling

Frequent collaborators in their research include Darin J. Knapp, David H. Overstreet, Hugh E. Criswell, Kathryn M. Harper, and Todd E. Thiele.

The publication record includes a mix of articles appearing mostly in UNC Libraries, with at least one paper published in Frontiers in Cellular Neuroscience. Examples of recent papers authored or co-authored by George R. Breese are:

  • 6-Hydroxydopamine Treatments Enhance Behavioral Responses to Intracerebral Microinjection of D1- and D2-Dopamine Agonists into Nucleus Accumbens and Striatum Without Changing Dopamine Antagonist Binding, 2020, UNC Libraries
  • Phenotyping CCL2 Containing Central Amygdala Neurons Controlling Alcohol Withdrawal-Induced Anxiety, 2020, Frontiers in Cellular Neuroscience
  • Topographic patterns of brain activity in response to swim stress: assessment by 2-deoxyglucose uptake and expression of Fos-like immunoreactivity, 2021, UNC Libraries
  • Self-complementary adeno-associated virus serotype 2 vector: global distribution and broad dispersion of AAV-mediated transgene expression in mouse brain, 2021, UNC Libraries
  • Site-Specific Enhancement of γ-Aminobutyric Acid-Mediated Inhibition of Neural Activity by Ethanol in the Rat Medial Septal Area, 2020, UNC Libraries

Their research contributes to understanding the neurochemical and behavioral mechanisms underlying stress, neurotransmitter receptor functions, and the physiological effects of substances like ethanol in brain areas involved in behavior and addiction. The emphasis on receptor mechanisms and signaling pathways supports work across multiple neuroscience subfields.

Best Publications

  • Systemic LPS Causes Chronic Neuroinflammation and Progressive Neurodegeneration

    Liya Qin;Xuefei Wu;Michelle L. Block;Yuxin Liu;Yuxin Liu

  • Effects of thyrotropin-releasing hormone in depression.

    A.J. Prange;P.P. Lara;I.C. Wilson;L.B. Alltop

  • Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector.

    Thomas J Mccown;Xiao Xiao;Juan Li;George R Breese

  • Enkephalin action on the mesolimbic system: a dopamine-dependent and a dopamine-independent increase in locomotor activity.

    Peter W Kalivas;Erik Widerlöv;Donald Stanley;George Breese

  • Metabolism of normetanephrine-H3 in rat brain--identification of conjugated 3-methoxy-4-hydrophenylglycol as the major metabolite

    Saul M. Schanberg;Joseph J. Schildkraut;George R. Breese;Irwin J. Kopin

  • Neuroanatomical characterization of Fos induction in rat behavioral models of anxiety.

    Gary E. Duncan;Darin J. Knapp;George R. Breese

  • Localization of D1 dopamine receptor mRNA in brain supports a role in cognitive, affective, and neuroendocrine aspects of dopaminergic neurotransmission.

    Robert T. Fremeau;Gary E Duncan;Maria Gioia Fornaretto;Allen Dearry

  • Effects of thyrotropin-releasing hormone (TRH) on the actions of pentobarbital and other centrally acting drugs.

    George R. Breese;Jerry M. Cott;Barrett R. Cooper;Arthur J. Prange

  • Behavioral differences between neonatal and adult 6-hydroxydopamine-treated rats to dopamine agonists: relevance to neurological symptoms in clinical syndromes with reduced brain dopamine.

    George R. Breese;Alan A. Baumeister;Thomas J. McCOWN;Susan G. Emerick

  • Thyrotropin releasing hormone: enhancement of dopa activity by a hypothalamic hormone.

    N. P. Plotnikoff;A. J. Prange;G. R. Breese;M. S. Anderson

  • Effects of ethanol on ion channels.

    F T Crews;A L Morrow;H Criswell;G Breese

  • SELECTIVE RELEASE OF NEWLY SYNTHESIZED NOREPINEPHRINE FROM THE CAT SPLEEN DURING SYMPATHETIC NERVE STIMULATION

    Irwin J. Kopin;George R. Breese;Kenneth R. Krauss;Virginia K. Weise

  • Topographic patterns of brain activity in response to swim stress: assessment by 2-deoxyglucose uptake and expression of Fos-like immunoreactivity

    GE Duncan;KB Johnson;GR Breese

  • 3-methoxy-4-hydroxyphenylglycol sulfate in brain and cerebrospinal fluid.

    Saul M. Schanberg;George R. Breese;Joseph J. Schildkraut;Edna K. Gordon

  • Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse.

    George R. Breese;Rajita Sinha;Markus Heilig

  • Pharmacokinetics of methylphenidate in man, rat and monkey.

    W Wargin;K Patrick;C Kilts;C T Gualtieri

  • Stress enhancement of craving during sobriety: a risk for relapse.

    George R. Breese;Kathleen Chu;Christopher V. Dayas;Douglas Funk

  • Ontogeny of D1A and D2 dopamine receptor subtypes in rat brain using in situ hybridization and receptor binding.

    U.B. Schambra;G.E. Duncan;G.R. Breese;M.G. Fornaretto

  • Thyrotropin releasing hormone: Antagonism of pentobarbital in rodents

    Arthur J. Prange;George R. Breese;Jerry M. Cott;Billy R. Martin

  • 6-hydroxydopamine treatments enhance behavioral responses to intracerebral microinjection of D1- and D2-dopamine agonists into nucleus accumbens and striatum without changing dopamine antagonist binding.

    G R Breese;G E Duncan;T C Napier;S C Bondy

Frequent Co-Authors

Gary E. Duncan
Gary E. Duncan University of North Carolina at Chapel Hill
Richard B. Mailman
Richard B. Mailman Pennsylvania State University
Arthur J. Prange
Arthur J. Prange University of North Carolina at Chapel Hill
David H. Overstreet
David H. Overstreet University of North Carolina at Chapel Hill
Sheryl S. Moy
Sheryl S. Moy University of North Carolina at Chapel Hill
Walter E. Stumpf
Walter E. Stumpf University of North Carolina at Chapel Hill
Todd E. Thiele
Todd E. Thiele University of North Carolina at Chapel Hill
Robert E. Chapin
Robert E. Chapin Pfizer (United States)
Charles B. Nemeroff
Charles B. Nemeroff The University of Texas at Austin
Irwin J. Kopin
Irwin J. Kopin National Institutes of Health

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