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Biology and Biochemistry

D-Index
43
Citations
7163
World Ranking
19399
National Ranking
309

Overview

Magnus Åbrink is affiliated with the Swedish University of Agricultural Sciences in Sweden. Their research spans the fields of Medicine and Immunology and Microbiology, with a particular focus on parasitology and immunological processes.

The main topics of their work include:

  • Mast cells and histamine
  • Parasites and Host Interactions
  • Parasitic Infections and Diagnostics
  • Helminth infection and control
  • Food Allergy and Anaphylaxis Research
  • Genetics, Aging, and Longevity in Model Organisms
  • Allergic Rhinitis and Sensitization

Magnus Åbrink has contributed to a range of publications in venues such as:

  • PLoS ONE
  • International Journal of Molecular Sciences
  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries

Some of their recent papers include:

  • Ivermectin-induced gene expression changes in adult Parascaris univalens and Caenorhabditis elegans: a comparative approach to study anthelminthic metabolism and resistance in vitro (2022, Parasites & Vectors)
  • The Chymase Mouse Mast Cell Protease-4 Regulates Intestinal Cytokine Expression in Mature Adult Mice Infected with Giardia intestinalis (2020, Cells)
  • Mast Cells Limit Ear Swelling Independently of the Chymase Mouse Mast Cell Protease 4 in an MC903-Induced Atopic Dermatitis-Like Mouse Model (2020, International Journal of Molecular Sciences)
  • Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain (2023, PLoS ONE)
  • Mast Cell Chymase/Mcpt4 Suppresses the Host Immune Response to Plasmodium yoelii, Limits Malaria-Associated Disruption of Intestinal Barrier Integrity and Reduces Parasite Transmission to Anopheles stephensi (2022, Frontiers in Immunology)

Their frequent co-authors include:

  • Staffan G. Svärd
  • Faruk Dube
  • Andrea Hinas
  • Eva Tydén
  • Frida Martin

Magnus Åbrink's research integrates immunological mechanisms involving mast cells with parasitological studies, notably exploring host-immune interactions and responses to parasitic infections. The work covers genetic and molecular approaches to understanding disease control and allergic conditions, reflecting a multidisciplinary approach spanning several subfields such as parasitology, immunology, and genetics.

Best Publications

  • Mast Cells Can Enhance Resistance to Snake and Honeybee Venoms

    Martin Metz;Adrian M. Piliponsky;Ching-Cheng Chen;Verena Lammel

  • A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2.

    Elena Tchougounova;Anders Lundequist;Ignacio Fajardo;Jan-Olof Winberg

  • The 5'-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle.

    Brian R. Barnes;Stefan Marklund;Tatiana L. Steiler;Mark Walter

  • Mast cell proteases.

    Gunnar Pejler;Magnus Abrink;Maria Ringvall;Sara Wernersson

  • Targeted Disruption of a Murine Glucuronyl C5-epimerase Gene Results in Heparan Sulfate Lacking l-Iduronic Acid and in Neonatal Lethality

    Jin-Ping Li;Feng Gong;Åsa Hagner-McWhirter;Erik Forsberg

  • Serglycin is essential for maturation of mast cell secretory granule.

    Magnus Åbrink;Mirjana Grujic;Gunnar Pejler

  • The Chymase, Mouse Mast Cell Protease 4, Constitutes the Major Chymotrypsin-like Activity in Peritoneum and Ear Tissue. A Role for Mouse Mast Cell Protease 4 in Thrombin Regulation and Fibronectin Turnover

    Elena Tchougounova;Gunnar Pejler;Magnus Åbrink

  • Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism

    Katherine R. Groschwitz;Richard Ahrens;Heather Osterfeld;Michael F. Gurish

  • Rab27b regulates number and secretion of platelet dense granules

    Tanya Tolmachova;Magnus Åbrink;Clare E. Futter;Kalwant S. Authi

  • KRAB Zinc Finger Proteins: An Analysis of the Molecular Mechanisms Governing Their Increase in Numbers and Complexity During Evolution

    Camilla Looman;Magnus Åbrink;Charlotta Mark;Lars Hellman

  • Critical Role of Mast Cell Chymase in Mouse Abdominal Aortic Aneurysm Formation

    Jiusong Sun;Jie Zhang;Jes Sanddal Lindholt;Galina K Sukhova

  • Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice

    Mitsuteru Akahoshi;Chang Ho Song;Chang Ho Song;Adrian M. Piliponsky;Adrian M. Piliponsky;Martin Metz;Martin Metz

  • Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis.

    Adrian M. Piliponsky;Ching Cheng Chen;Toshihiko Nishimura;Martin Metz

  • Mast Cell Chymase Degrades the Alarmins Heat Shock Protein 70, Biglycan, HMGB1, and Interleukin-33 (IL-33) and Limits Danger-induced Inflammation *

    Ananya Roy;Goutham Ganesh;Helena Sippola;Sara Bolin

  • Independent degeneration of photoreceptors and retinal pigment epithelium in conditional knockout mouse models of choroideremia.

    Tanya Tolmachova;Ross Anders;Magnus Abrink;Laurence Bugeon

  • Human cell lines U-937, THP-1 and Mono Mac 6 represent relatively immature cells of the monocyte-macrophage cell lineage.

    M. Abrink;A. E. Gobl;Ranyang Huang;K. Nilsson

  • Serglycin-deficient Cytotoxic T Lymphocytes Display Defective Secretory Granule Maturation and Granzyme B Storage

    Mirjana Grujic;Tiago Braga;Agneta Lukinius;Maija-Leena Eloranta

  • The Chymase Mouse Mast Cell Protease 4 Degrades TNF, Limits Inflammation, and Promotes Survival in a Model of Sepsis

    Adrian M. Piliponsky;Adrian M. Piliponsky;Ching Cheng Chen;Ching Cheng Chen;Eon J. Rios;Piper M. Treuting

  • Rab27b regulates mast cell granule dynamics and secretion

    Kouichi Mizuno;Tanya Tolmachova;Dmitry S. Ushakov;Maryse Romao

  • Serotonin and histamine storage in mast cell secretory granules is dependent on serglycin proteoglycan.

    Maria Ringvall;Elin Rönnberg;Sara Wernersson;Annette Duelli

Frequent Co-Authors

Gunnar Pejler
Gunnar Pejler Uppsala University
Lars Hellman
Lars Hellman Uppsala University
Ulrich Blank
Ulrich Blank Université Paris Cité
Lena Kjellén
Lena Kjellén Uppsala University
Mindy Tsai
Mindy Tsai Stanford University
Michael F. Gurish
Michael F. Gurish Harvard Medical School
Stephen J. Galli
Stephen J. Galli Stanford University
Martin Metz
Martin Metz Charité - University Medicine Berlin
Miguel C. Seabra
Miguel C. Seabra Universidade Nova de Lisboa
Staffan G. Svärd
Staffan G. Svärd Uppsala University

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