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Neuroscience

D-Index
73
Citations
17940
World Ranking
2213
National Ranking
1052

Overview

Richard B. Mailman is affiliated with Pennsylvania State University in the United States. Their research primarily focuses on the fields of Medicine and Neuroscience, with significant contributions to subfields including Neurology, Cognitive Neuroscience, Cellular and Molecular Neuroscience, Molecular Biology, and Radiology, Nuclear Medicine and Imaging.

The main topics covered in Richard B. Mailman's work include:

  • Parkinson's Disease Mechanisms and Treatments
  • Neurological disorders and treatments
  • Receptor Mechanisms and Signaling
  • Functional Brain Connectivity Studies
  • Advanced Neuroimaging Techniques and Applications
  • Trace Elements in Health
  • Heavy Metal Exposure and Toxicity

Their recent publications reflect a focus on Parkinson's disease and brain activity, including:

  • "Decoupling of Global Brain Activity and Cerebrospinal Fluid Flow in Parkinson's Disease Cognitive Decline" (2021, Movement Disorders)
  • "Dynamics of Nigral Iron Accumulation in Parkinson's Disease: From Diagnosis to Late Stage" (2022, Movement Disorders)
  • "Resting-state global brain activity affects early β-amyloid accumulation in default mode network" (2023, Nature Communications)
  • "The D1/D5 Dopamine Partial Agonist PF-06412562 in Advanced-Stage Parkinson's Disease: A Feasibility Study" (2020, Journal of Parkinson's Disease)
  • "D1, not D2, dopamine receptor activation dramatically improves MPTP-induced parkinsonism unresponsive to levodopa" (2020, European Journal of Pharmacology)

Frequent collaborators in their research include:

  • Xuemei Huang
  • Mechelle M. Lewis
  • Lan Kong
  • Guangwei Du
  • Yang Yang

Richard B. Mailman has published extensively in various venues, with notable frequency in:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Movement Disorders
  • Advances in Medical Education and Practice
  • Parkinsonism & Related Disorders

Best Publications

  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology

    Jonathan D. Urban;William P. Clarke;Mark Von Zastrow;David E. Nichols

  • Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology.

    David A. Shapiro;Sean Renock;Elaine Arrington;Louis A. Chiodo

  • Interactions of the novel antipsychotic aripiprazole (OPC-14597) with dopamine and serotonin receptor subtypes.

    Cindy P Lawler;Cassandra Prioleau;Mechelle M Lewis;Chun Mak

  • Third Generation Antipsychotic Drugs: Partial Agonism or Receptor Functional Selectivity?

    Richard B. Mailman;Vishakantha Murthy

  • Serotonergic basis of antipsychotic drug effects in schizophrenia

    Jeffrey A Lieberman;Richard B Mailman;Gary Duncan;Lin Sikich

  • Behavioural assessment of mice lacking D1A dopamine receptors

    D.R Smith;C.D Striplin;A.M Geller;R.B Mailman

  • Smoking duration, intensity, and risk of Parkinson disease

    H. Chen;X. Huang;X. Guo;R. B. Mailman

  • Aripiprazole has functionally selective actions at dopamine D2 receptor-mediated signaling pathways

    Jonathan D Urban;Gabriel A Vargas;Mark von Zastrow;Richard B Mailman

  • AF64A, a cholinergic neurotoxin, selectively depletes acetylcholine in hippocampus and cortex, and produces long-term passive avoidance and radial-arm maze deficits in the rat.

    Thomas J. Walsh;Hugh A. Tilson;Diane L. DeHaven;Richard B. Mailman

  • Simultaneous quantification of dopamine, 5-hydroxytryptaine and four metabolically related compounds by means of reversed-phase high-performance liquid chromatography with electrochemical detection

    Clinton D. Kilts;George R. Breese;Richard B. Mailman

  • Lower low-density lipoprotein cholesterol levels are associated with Parkinson's disease.

    Xuemei Huang;Honglei Chen;William C. Miller;Richard B. Mailman

  • GPCR functional selectivity has therapeutic impact

    Richard B. Mailman

  • Interactions of neurotensin with brain dopamine systems: biochemical and behavioral studies.

    C. B. Nemeroff;D. Luttinger;D. E. Hernandez;Richard Mailman

  • SCH-23390: A selective D1 dopamine antagonist with potent D2 behavioral actions

    Richard B. Mailman;David W. Schulz;Mark H. Lewis;Laura Staples

  • Dihydrexidine, a full dopamine D1 agonist, reduces MPTP-ioduced parkinsonism in monkeys

    Jane R. Taylor;Matthew S. Lawrence;D.Eugene Redmond;John D. Elsworth

  • Novel Dopamine Therapeutics for Cognitive Deficits in Schizophrenia

    Amy F.T. Arnsten;Ragy R. Girgis;David L. Gray;Richard B. Mailman

  • Low LDL cholesterol and increased risk of Parkinson's disease: prospective results from Honolulu-Asia Aging Study

    Xuemei Huang;Robert D. Abbott;Robert D. Abbott;Robert D. Abbott;Helen Petrovitch;Richard B. Mailman

  • D1 and D2 dopamine receptors independently regulate spontaneous blink rate in the vervet monkey.

    J. D. Elsworth;M. S. Lawrence;R. H. Roth;J. R. Taylor

  • Statins, plasma cholesterol, and risk of Parkinson's disease: a prospective study.

    Xuemei Huang;Alvaro Alonso;Xuguang Guo;David M. Umbach

  • Task specific influences of Parkinson’s disease on the striato-thalamo-cortical and cerebello-thalamo-cortical motor circuitries

    M.M. Lewis;C.G. Slagle;A.B. Smith;Y. Truong

  • Quantitative Susceptibility Mapping of the Midbrain in Parkinson’s Disease

    Guangwei Du;Tian Liu;Mechelle M. Lewis;Lan Kong

  • Differential involvement of striato- and cerebello-thalamo-cortical pathways in tremor-and akinetic/rigid-predominant Parkinson's disease

    Mechelle M. Lewis;Guangwei Du;Suman Sen;Suman Sen;Atsushi Kawaguchi

  • Long-Term Effects of Early Social Isolation in Macaca mulatta: Changes in Dopamine Receptor Function Following Apomorphine Challenge

    Mark H. Lewis;John P. Gluck;Alan J. Beauchamp;Michael F. Keresztury

Frequent Co-Authors

Xuemei Huang
Xuemei Huang Pennsylvania State University
Mechelle M. Lewis
Mechelle M. Lewis Penn State Milton S. Hershey Medical Center
Mark H. Lewis
Mark H. Lewis University of Florida
Paul J. Eslinger
Paul J. Eslinger Penn State Milton S. Hershey Medical Center
Gary E. Duncan
Gary E. Duncan University of North Carolina at Chapel Hill
Thomas J. Walsh
Thomas J. Walsh Weill Cornell Medicine
John Drago
John Drago University of Melbourne
James W. Bodfish
James W. Bodfish Vanderbilt University Medical Center
John D. Elsworth
John D. Elsworth Yale University
Sara R. Jones
Sara R. Jones Wake Forest University

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