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Neuroscience
Ireland
2026

D-Index & Metrics

Neuroscience

D-Index
89
Citations
38782
World Ranking
1132
National Ranking
3

Medicine

D-Index
89
Citations
38705
World Ranking
12488
National Ranking
33

Research.com Recognitions

  • 2026 - Research.com Neuroscience in Ireland Leader Award
  • 2025 - Research.com Neuroscience in Ireland Leader Award
  • 2003 - Member of the Royal Irish Academy

Overview

John L. Waddington is affiliated with the Royal College of Surgeons in Ireland. Their research spans multiple fields primarily within Medicine and Neuroscience, with a focus on Psychiatry and Mental Health, Neurology, Cellular and Molecular Neuroscience, Molecular Biology, and Cognitive Neuroscience.

The main topics addressed in Waddington's work include:

  • Schizophrenia research and treatment
  • Bipolar Disorder and Treatment
  • Neurological disorders and treatments
  • Functional Brain Connectivity Studies
  • Mental Health Research Topics
  • Tryptophan and brain disorders
  • Regulation of Appetite and Obesity

Frequent publication venues associated with Waddington encompass:

  • Schizophrenia Research
  • European Neuropsychopharmacology
  • Acta Pharmacologica Sinica
  • bioRxiv (Cold Spring Harbor Laboratory)
  • American Journal of Psychiatry

Notable recent papers include:

  • Psychosis in Parkinson's disease and parkinsonism in antipsychotic-naive schizophrenia spectrum psychosis: clinical, nosological and pathobiological challenges, 2020, Acta Pharmacologica Sinica
  • DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia, 2021, eLife
  • Movement disorder and sensorimotor abnormalities in schizophrenia and other psychoses - European consensus on assessment and perspectives, 2020, European Neuropsychopharmacology
  • 20-Year Prospective, Sequential Follow-Up Study of Heterogeneity in Associations of Duration of Untreated Psychosis With Symptoms, Functioning, and Quality of Life Following First-Episode Psychosis, 2022, American Journal of Psychiatry
  • Development and characterization of an inducible Dicer conditional knockout mouse model of Parkinson's disease: validation of the antiparkinsonian effects of a sigma-1 receptor agonist and dihydromyricetin, 2020, Acta Pharmacologica Sinica

Frequent collaborators include Vincent Russell, Anthony Kinsella, Nnamdi Nkire, Xuechu Zhen, and Dušan Hirjak.

John L. Waddington was recognized as a Member of the Royal Irish Academy in 2003.

Best Publications

  • Biological insights from 108 schizophrenia-associated genetic loci

    Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Aiden Corvin;James T. R. Walters

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev

  • Rare chromosomal deletions and duplications increase risk of schizophrenia

    Jennifer L. Stone;Jennifer L. Stone;Jennifer L. Stone;Michael C. O’Donovan;Hugh Gurling;George K. Kirov

  • Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

    Christian R Marshall;Daniel P Howrigan;Daniel P Howrigan;Daniele Merico;Bhooma Thiruvahindrapuram

  • Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

    Douglas M. Ruderfer;Stephan Ripke;Stephan Ripke;Stephan Ripke;Andrew McQuillin;James Boocock

  • Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects

    Eva M Jimenez-Mateos;Tobias Engel;Paula Merino-Serrais;Ross C McKiernan

  • Dopaminergic behaviour stereospecifically promoted by the D1 agonist R-SK & F 38393 and selectively blocked by the D1 antagonist SCH 23390

    Anthony G. Molloy;John L. Waddington

  • Mortality in schizophrenia. Antipsychotic polypharmacy and absence of adjunctive anticholinergics over the course of a 10-year prospective study.

    John L. Waddington;Hanafy A. Youssef;Anthony Kinsella

  • Phenotypic characterization of an alpha 4 neuronal nicotinic acetylcholine receptor subunit knock-out mouse.

    Shelley A. Ross;John Y. F. Wong;Jeremiah J. Clifford;Anthony Kinsella

  • Spontaneous orofacial movements induced in rodents by very long-term neuroleptic drug administration: phenomenology, pathophysiology and putative relationship to tardive dyskinesia

    John L. Waddington

  • Drugs acting on brain dopamine receptors: a conceptual re-evaluation five years after the first selective D-1 antagonist.

    John L. Waddington;Kathy M. O'Boyle

  • Schizophrenia and the city: A review of literature and prospective study of psychosis and urbanicity in Ireland

    Brendan D. Kelly;Brendan D. Kelly;Brendan D. Kelly;Eadbhard O'Callaghan;Eadbhard O'Callaghan;John L. Waddington;Larkin Feeney

  • The induction of grooming and vacuous chewing by a series of selective D-1 dopamine receptor agonists: two directions of D-1:D-2 interaction.

    Angela M. Murray;John L. Waddington

  • Phenotypic characterization of spatial cognition and social behavior in mice with 'knockout' of the schizophrenia risk gene neuregulin 1.

    Colm M O'Tuathaigh;Daniela Babovic;Gerard J O'Sullivan;Jeremiah J Clifford

  • Beyond the critical period: longitudinal study of 8-year outcome in first-episode non-affective psychosis.

    Niall Crumlish;Peter Whitty;Mary Clarke;Stephen Browne

  • Behavioural effects of the putative D-3 dopamine receptor agonist 7-OH-DPAT in relation to other “D-2-like” agonists

    Siobhan A. Daly;John L. Waddington

  • Determinants of quality of life at first presentation with schizophrenia

    Stephen Browne;Mary Clarke;Maurice Gervin;John L. Waddington

  • Complement genes contribute sex-biased vulnerability in diverse disorders

    Nolan Kamitaki;Nolan Kamitaki;Aswin Sekar;Aswin Sekar;Robert E. Handsaker;Robert E. Handsaker;Heather de Rivera;Heather de Rivera

  • Effects of the putative D-1 antagonist SCH 23390 on stereotyped behaviour induced by the D-2 agonist RU24213.

    Mark T. Pugh;Kathy M. O'Boyle;Anthony G. Molloy;John L. Waddington

  • Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene (DTNBP1).

    N. M. Williams;A Preece;D. W. Morris;G. Spurlock

Frequent Co-Authors

Derek W. Morris
Derek W. Morris University of Galway
Aiden Corvin
Aiden Corvin Trinity College Dublin
Michael Gill
Michael Gill Trinity College Dublin
Gary Donohoe
Gary Donohoe University of Galway
John Drago
John Drago University of Melbourne
Timothy G. Dinan
Timothy G. Dinan University College Cork
Michael Conlon O'Donovan
Michael Conlon O'Donovan Cardiff University
Tune H. Pers
Tune H. Pers University of Copenhagen
Danielle Posthuma
Danielle Posthuma Vrije Universiteit Amsterdam
Jim van Os
Jim van Os University Medical Center Utrecht

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